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• W2130487415 abstract "The formation of amyloid fibres is a hallmark of amyloid disorders. Nevertheless, the lack of correlation between fibre load and disease as observed, for example, in Alzheimer's disease, means that fibres are considered secondary contributors to the onset of cellular dysfunction. Instead, soluble intermediates of amyloid assembly are often described as the agents of toxicity. Here, we discuss recent experimental discoveries which suggest that amyloid fibres should be considered as disease-relevant species that can mediate a range of pathological processes. These include disruption of biological membranes, secondary nucleation, amyloid aggregate transmission, and the disruption of protein homeostasis (proteostasis). Thus, a greater understanding of amyloid fibre biology could enhance prospects of developing therapeutic interventions against this devastating class of protein-misfolding disorders." @default.
• W2130487415 created "2016-06-24" @default.
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• W2130487415 creator A5074934123 @default.
• W2130487415 creator A5087275613 @default.
• W2130487415 date "2015-12-01" @default.
• W2130487415 modified "2023-10-14" @default.
• W2130487415 title "Amyloid Fibres: Inert End-Stage Aggregates or Key Players in Disease?" @default.
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• W2130487415 cites W1972439404 @default.
• W2130487415 cites W1973056215 @default.
• W2130487415 cites W1974059817 @default.
• W2130487415 cites W1975315404 @default.
• W2130487415 cites W1977267085 @default.
• W2130487415 cites W1980115442 @default.
• W2130487415 cites W1981580199 @default.
• W2130487415 cites W1982487616 @default.
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• W2130487415 cites W1995191747 @default.
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• W2130487415 doi "https://doi.org/10.1016/j.tibs.2015.10.002" @default.
• W2130487415 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26541462" @default.
• W2130487415 hasPublicationYear "2015" @default.
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