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• W2130487729 abstract "Although the various coagulation factors are present at physiological concentrations in fresh-frozen plasma (FFP) derived from healthy blood donors, some virally inactivated plasma-derived coagulation factor concentrates have been available for many years. These latter products include single coagulation factor concentrates (such as factor VIII concentrates for the treatment of haemophilia A and factor IX concentrate for the treatment of haemophilia B) or the so-called prothrombin complex concentrates (PCC), which are intermediate purity pooled plasma products containing a mixture of vitamin K-dependent proteins1,2.This review will focus on the description of PCC, on their indications and safety. It will not address activated PCC for the treatment of patients with clotting factor inhibitors." @default.
• W2130487729 created "2016-06-24" @default.
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• W2130487729 creator A5073522064 @default.
• W2130487729 date "2010-07-01" @default.
• W2130487729 modified "2023-09-28" @default.
• W2130487729 title "Prothrombin complex concentrates: an update." @default.
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• W2130487729 doi "https://doi.org/10.2450/2010.0149-09" @default.
• W2130487729 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2906185" @default.
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• W2130487729 hasPublicationYear "2010" @default.
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