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- W2130584672 abstract "Epstein-Barr virus (EBV) is a ubiquitous, gamma-1 lymphotrophic virus etiologically linked to nasopharyngeal carcinoma (NPC), endemic to Southern China, and Burkitt lymphoma (BL), endemic to equatorial Africa, both of which are rare elsewhere in the world. Why EBV is associated with different malignancies in different geographic regions remains puzzling and may be related to EBV genotypic variability through specific disease and geographic associations. We review the literature on sequence variation in EBV genes, focusing on LMP-1, EBNA-1, and BZLF-1 and their distribution by geography and disease. Given the limitations of current studies, definitive conclusions regarding the link between EBV genotypes, disease and geography are not possible. We suggest that the true extent of EBV diversity is likely to be greater than is currently recognized. Additional studies conducted in carefully selected populations, that are sufficiently powered to provide robust estimates, and that utilize testing approaches that permit full characterization of viral diversity are needed to further our understanding of patterns of EBV genetic variation and their association with malignancies in different regions." @default.
- W2130584672 created "2016-06-24" @default.
- W2130584672 creator A5017664007 @default.
- W2130584672 creator A5039411132 @default.
- W2130584672 creator A5053917890 @default.
- W2130584672 creator A5058471166 @default.
- W2130584672 creator A5067759844 @default.
- W2130584672 date "2009-08-01" @default.
- W2130584672 modified "2023-10-13" @default.
- W2130584672 title "The extent of genetic diversity of Epstein-Barr virus and its geographic and disease patterns: A need for reappraisal" @default.
- W2130584672 cites W1480250972 @default.
- W2130584672 cites W1488068570 @default.
- W2130584672 cites W1498935511 @default.
- W2130584672 cites W1565475710 @default.
- W2130584672 cites W1567848837 @default.
- W2130584672 cites W1573217573 @default.
- W2130584672 cites W1578036061 @default.
- W2130584672 cites W1594783842 @default.
- W2130584672 cites W1672761980 @default.
- W2130584672 cites W1706373226 @default.
- W2130584672 cites W1753716921 @default.
- W2130584672 cites W1754574375 @default.
- W2130584672 cites W1763086440 @default.
- W2130584672 cites W1770825651 @default.
- W2130584672 cites W1796088623 @default.
- W2130584672 cites W1814273895 @default.
- W2130584672 cites W1844848296 @default.
- W2130584672 cites W1912413803 @default.
- W2130584672 cites W191670532 @default.
- W2130584672 cites W1925065715 @default.
- W2130584672 cites W1946498671 @default.
- W2130584672 cites W1965154781 @default.
- W2130584672 cites W1966547053 @default.
- W2130584672 cites W1967366275 @default.
- W2130584672 cites W1970827689 @default.
- W2130584672 cites W1973377363 @default.
- W2130584672 cites W1974556597 @default.
- W2130584672 cites W1975007323 @default.
- W2130584672 cites W1977562050 @default.
- W2130584672 cites W1978905721 @default.
- W2130584672 cites W1979401674 @default.
- W2130584672 cites W1980464074 @default.
- W2130584672 cites W1981201050 @default.
- W2130584672 cites W1981458937 @default.
- W2130584672 cites W1981695407 @default.
- W2130584672 cites W1981807499 @default.
- W2130584672 cites W1982103225 @default.
- W2130584672 cites W1982627147 @default.
- W2130584672 cites W1984741210 @default.
- W2130584672 cites W1985206548 @default.
- W2130584672 cites W1986679518 @default.
- W2130584672 cites W1990475908 @default.
- W2130584672 cites W1991051808 @default.
- W2130584672 cites W1992558659 @default.
- W2130584672 cites W1992627272 @default.
- W2130584672 cites W1997010494 @default.
- W2130584672 cites W1997467195 @default.
- W2130584672 cites W1998701913 @default.
- W2130584672 cites W2000494870 @default.
- W2130584672 cites W2000826701 @default.
- W2130584672 cites W2001125223 @default.
- W2130584672 cites W2003750162 @default.
- W2130584672 cites W2005800417 @default.
- W2130584672 cites W2008333420 @default.
- W2130584672 cites W2010488262 @default.
- W2130584672 cites W2013536390 @default.
- W2130584672 cites W2013586951 @default.
- W2130584672 cites W2013597873 @default.
- W2130584672 cites W2020001103 @default.
- W2130584672 cites W2021084411 @default.
- W2130584672 cites W2021464282 @default.
- W2130584672 cites W2023384188 @default.
- W2130584672 cites W2024492013 @default.
- W2130584672 cites W2024910690 @default.
- W2130584672 cites W2025944440 @default.
- W2130584672 cites W2026640960 @default.
- W2130584672 cites W2026714592 @default.
- W2130584672 cites W2029297598 @default.
- W2130584672 cites W2035511781 @default.
- W2130584672 cites W2035897912 @default.
- W2130584672 cites W2037136073 @default.
- W2130584672 cites W2041345810 @default.
- W2130584672 cites W2046282113 @default.
- W2130584672 cites W2047184081 @default.
- W2130584672 cites W2047197428 @default.
- W2130584672 cites W2048905748 @default.
- W2130584672 cites W2049123465 @default.
- W2130584672 cites W2050353727 @default.
- W2130584672 cites W2055486609 @default.
- W2130584672 cites W2060001883 @default.
- W2130584672 cites W2060876478 @default.
- W2130584672 cites W2062434608 @default.
- W2130584672 cites W2063175140 @default.
- W2130584672 cites W2063393908 @default.
- W2130584672 cites W2068774350 @default.
- W2130584672 cites W2069854304 @default.
- W2130584672 cites W2070420459 @default.
- W2130584672 cites W2070479696 @default.