Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130586809> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2130586809 endingPage "626" @default.
- W2130586809 startingPage "626" @default.
- W2130586809 abstract "In India, hemoglobinopathies constitute a major genetic disorder and hemoglobin variants such as Hb S, Hb D Punjab, and Hb E are the most common ones. Other variants include Hb Q India, Hb Lepore, Hb J Meerut, Hb D Iran, etc. These variants show heterozygous state along with beta thalassemia. However, compound heterozygosities among these variants are very rare. Ethylenediaminetetraacetic acid whole blood sample received for routine thalassemia screening was subjected to alkaline electrophoresis using automated capillary zone electrophoresis. Suspecting the presence of rare variants, further analysis was carried out using Bio-Rad D10 and Tosoh G8 high-performance liquid chromatography (HPLC) systems. Capillary zone electrophoretograms showed the presence of peaks in zone Hb A, Hb D, a fused peak in Hb A2, and a small peak in Z1 zone. Bio-Rad and Tosoh chromatograms also indicated the presence of four peaks which are identified as Hb A, Hb D Punjab, Hb Q India, and hybrid of Hb D Punjab/Hb Q India. A peak in Hb D zone of capillary was due to co-migration of Hb D Punjab and Hb Q India variants. Small peak in Z1 zone indicated the presence of alpha chain variant Hb Q India. The findings were further confirmed by HPLC results and molecular genetic studies. The present study reports for the 1 <sup>st</sup> time a rare hemoglobinopathy of double heterozygosity for Hb D Punjab, Hb Q India on Capillarys 2 Flex Piercing analyzer and is forth reported case for this rare hemoglobinopathy." @default.
- W2130586809 created "2016-06-24" @default.
- W2130586809 creator A5036851700 @default.
- W2130586809 creator A5042725690 @default.
- W2130586809 creator A5048504394 @default.
- W2130586809 creator A5080872858 @default.
- W2130586809 date "2014-01-01" @default.
- W2130586809 modified "2023-09-23" @default.
- W2130586809 title "Diagnosis of a rare double heterozygous Hb D Punjab/Hb Q India hemoglobinopathy using Sebia capillary zone electrophoresis" @default.
- W2130586809 cites W1989297636 @default.
- W2130586809 cites W1993428040 @default.
- W2130586809 cites W2070623409 @default.
- W2130586809 cites W2120779973 @default.
- W2130586809 cites W2125280117 @default.
- W2130586809 doi "https://doi.org/10.4103/0377-4929.142709" @default.
- W2130586809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25308024" @default.
- W2130586809 hasPublicationYear "2014" @default.
- W2130586809 type Work @default.
- W2130586809 sameAs 2130586809 @default.
- W2130586809 citedByCount "3" @default.
- W2130586809 countsByYear W21305868092015 @default.
- W2130586809 countsByYear W21305868092017 @default.
- W2130586809 countsByYear W21305868092018 @default.
- W2130586809 crossrefType "journal-article" @default.
- W2130586809 hasAuthorship W2130586809A5036851700 @default.
- W2130586809 hasAuthorship W2130586809A5042725690 @default.
- W2130586809 hasAuthorship W2130586809A5048504394 @default.
- W2130586809 hasAuthorship W2130586809A5080872858 @default.
- W2130586809 hasBestOaLocation W21305868091 @default.
- W2130586809 hasConcept C104317684 @default.
- W2130586809 hasConcept C126322002 @default.
- W2130586809 hasConcept C143589142 @default.
- W2130586809 hasConcept C153911025 @default.
- W2130586809 hasConcept C180754005 @default.
- W2130586809 hasConcept C185592680 @default.
- W2130586809 hasConcept C2776175824 @default.
- W2130586809 hasConcept C2776920385 @default.
- W2130586809 hasConcept C2777799968 @default.
- W2130586809 hasConcept C2778917026 @default.
- W2130586809 hasConcept C2779668550 @default.
- W2130586809 hasConcept C2900643 @default.
- W2130586809 hasConcept C43617362 @default.
- W2130586809 hasConcept C54355233 @default.
- W2130586809 hasConcept C55493867 @default.
- W2130586809 hasConcept C71924100 @default.
- W2130586809 hasConcept C86803240 @default.
- W2130586809 hasConceptScore W2130586809C104317684 @default.
- W2130586809 hasConceptScore W2130586809C126322002 @default.
- W2130586809 hasConceptScore W2130586809C143589142 @default.
- W2130586809 hasConceptScore W2130586809C153911025 @default.
- W2130586809 hasConceptScore W2130586809C180754005 @default.
- W2130586809 hasConceptScore W2130586809C185592680 @default.
- W2130586809 hasConceptScore W2130586809C2776175824 @default.
- W2130586809 hasConceptScore W2130586809C2776920385 @default.
- W2130586809 hasConceptScore W2130586809C2777799968 @default.
- W2130586809 hasConceptScore W2130586809C2778917026 @default.
- W2130586809 hasConceptScore W2130586809C2779668550 @default.
- W2130586809 hasConceptScore W2130586809C2900643 @default.
- W2130586809 hasConceptScore W2130586809C43617362 @default.
- W2130586809 hasConceptScore W2130586809C54355233 @default.
- W2130586809 hasConceptScore W2130586809C55493867 @default.
- W2130586809 hasConceptScore W2130586809C71924100 @default.
- W2130586809 hasConceptScore W2130586809C86803240 @default.
- W2130586809 hasIssue "4" @default.
- W2130586809 hasLocation W21305868091 @default.
- W2130586809 hasLocation W21305868092 @default.
- W2130586809 hasLocation W21305868093 @default.
- W2130586809 hasOpenAccess W2130586809 @default.
- W2130586809 hasPrimaryLocation W21305868091 @default.
- W2130586809 hasRelatedWork W178305797 @default.
- W2130586809 hasRelatedWork W1833998540 @default.
- W2130586809 hasRelatedWork W1991989238 @default.
- W2130586809 hasRelatedWork W1992127363 @default.
- W2130586809 hasRelatedWork W2024788525 @default.
- W2130586809 hasRelatedWork W2281467146 @default.
- W2130586809 hasRelatedWork W2370289560 @default.
- W2130586809 hasRelatedWork W239302219 @default.
- W2130586809 hasRelatedWork W2765744510 @default.
- W2130586809 hasRelatedWork W4220841614 @default.
- W2130586809 hasVolume "57" @default.
- W2130586809 isParatext "false" @default.
- W2130586809 isRetracted "false" @default.
- W2130586809 magId "2130586809" @default.
- W2130586809 workType "article" @default.