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- W2130622075 abstract "Numerous studies have reported a smaller hippocampal volume in Alzheimer's disease (AD) patients than in aging controls. However, in mild cognitive impairment (MCI), the results are inconsistent. Moreover, the left-right asymmetry of the hippocampus receives less research attention. In this article, meta-analyses are designed to determine the extent of hippocampal atrophy in MCI and AD, and to evaluate the asymmetry pattern of the hippocampal volume in control, MCI, and AD groups. From 14 studies including 365 MCI patients and 382 controls, significant atrophy is found in both the left [Effect size (ES), 0.92; 95% confidence interval (CI), 0.72-1.11] and right (ES, 0.78; 95% CI, 0.57-0.98) hippocampus, which is lower than that in AD (ES, 1.60, 95% CI, 1.37-1.84, in left; ES, 1.52, 95% CI, 1.31-1.72, in right). Comparing with aging controls, the average volume reduction weighted by sample size is 12.9% and 11.1% in left and right hippocampus in MCI, and 24.2% and 23.1% in left and right hippocampus in AD, respectively. The findings show a bilateral hippocampal volume loss in MCI and the extent of atrophy is less than that in AD. By comparing the left and right hippocampal volume, a consistent left-less-than-right asymmetry pattern is found, but with different extents in control (ES, 0.39), MCI (ES, 0.56), and AD (ES, 0.30) group." @default.
- W2130622075 created "2016-06-24" @default.
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- W2130622075 date "2009-11-01" @default.
- W2130622075 modified "2023-10-14" @default.
- W2130622075 title "Hippocampal volume and asymmetry in mild cognitive impairment and Alzheimer's disease: Meta-analyses of MRI studies" @default.
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- W2130622075 cites W1978905248 @default.
- W2130622075 cites W1986295281 @default.
- W2130622075 cites W1989229423 @default.
- W2130622075 cites W1990752558 @default.
- W2130622075 cites W1992992703 @default.
- W2130622075 cites W1994547251 @default.
- W2130622075 cites W1997160768 @default.
- W2130622075 cites W2004079003 @default.
- W2130622075 cites W2006641848 @default.
- W2130622075 cites W2011068734 @default.
- W2130622075 cites W2015933608 @default.
- W2130622075 cites W2016150126 @default.
- W2130622075 cites W2018009442 @default.
- W2130622075 cites W2019039265 @default.
- W2130622075 cites W2021452267 @default.
- W2130622075 cites W2021656729 @default.
- W2130622075 cites W2021720039 @default.
- W2130622075 cites W2022113252 @default.
- W2130622075 cites W2033713584 @default.
- W2130622075 cites W2034241053 @default.
- W2130622075 cites W2040048921 @default.
- W2130622075 cites W2040812872 @default.
- W2130622075 cites W2045333811 @default.
- W2130622075 cites W2048172659 @default.
- W2130622075 cites W2053935454 @default.
- W2130622075 cites W2056313099 @default.
- W2130622075 cites W2058226627 @default.
- W2130622075 cites W2061647004 @default.
- W2130622075 cites W2061701872 @default.
- W2130622075 cites W2062535312 @default.
- W2130622075 cites W2066462635 @default.
- W2130622075 cites W2067140282 @default.
- W2130622075 cites W2069476204 @default.
- W2130622075 cites W2075061360 @default.
- W2130622075 cites W2077924486 @default.
- W2130622075 cites W2084453479 @default.
- W2130622075 cites W2087172160 @default.
- W2130622075 cites W2087567887 @default.
- W2130622075 cites W2092789470 @default.
- W2130622075 cites W2093488421 @default.
- W2130622075 cites W2106106014 @default.
- W2130622075 cites W2106775021 @default.
- W2130622075 cites W2116567545 @default.
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- W2130622075 cites W2136579519 @default.
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- W2130622075 cites W2145858412 @default.
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- W2130622075 cites W2158219747 @default.
- W2130622075 cites W2159122349 @default.
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- W2130622075 cites W2162936584 @default.
- W2130622075 cites W2163980871 @default.
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- W2130622075 doi "https://doi.org/10.1002/hipo.20573" @default.
- W2130622075 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19309039" @default.
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