Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130623426> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2130623426 endingPage "116" @default.
- W2130623426 startingPage "113" @default.
- W2130623426 abstract "There are two principal methods for valuing pharmaceutical R&D projects—discounted cash flow (DCF) and real options valuation (ROV). As typically practiced, DCF valuations tend to be lower than the estimates produced by ROV techniques. Part of the difference, as many have recognized, stems from DCF s limited ability to take account of managers' real option to cut its losses when new information reveals a drug candidate's lack of profit potential. Another reason for the difference, however, is the widespread use in DCF valuations of established success rates that do not distinguish between projects that fail to pass safety or efficacy trials and those that are abandoned for lack of economic viability. If the appropriate success rates are used, the two methods should yield identical project values because they assume the same scenarios. The practical reality, however, is that the two methods deal in a completely different way with the possibility of abandonment for economic reasons. Because ROV accounts for this possibility directly in the model itself, it is much better suited than DCF to this task—indeed, that is the uncertainty that it is designed to deal with. And the fact that 30% of all pharma R&D abandonments are for economic reasons is a strong argument for using ROV rather than DCF to evaluate new drug development." @default.
- W2130623426 created "2016-06-24" @default.
- W2130623426 creator A5000543332 @default.
- W2130623426 creator A5089234195 @default.
- W2130623426 date "2005-03-01" @default.
- W2130623426 modified "2023-09-25" @default.
- W2130623426 title "Valuing Pharma R&D: The Catch-22 of DCF" @default.
- W2130623426 doi "https://doi.org/10.1111/j.1745-6622.2005.00039.x" @default.
- W2130623426 hasPublicationYear "2005" @default.
- W2130623426 type Work @default.
- W2130623426 sameAs 2130623426 @default.
- W2130623426 citedByCount "8" @default.
- W2130623426 countsByYear W21306234262018 @default.
- W2130623426 countsByYear W21306234262019 @default.
- W2130623426 crossrefType "journal-article" @default.
- W2130623426 hasAuthorship W2130623426A5000543332 @default.
- W2130623426 hasAuthorship W2130623426A5089234195 @default.
- W2130623426 hasConcept C10138342 @default.
- W2130623426 hasConcept C144133560 @default.
- W2130623426 hasConcept C145424490 @default.
- W2130623426 hasConcept C154945302 @default.
- W2130623426 hasConcept C162118730 @default.
- W2130623426 hasConcept C162324750 @default.
- W2130623426 hasConcept C163428354 @default.
- W2130623426 hasConcept C175444787 @default.
- W2130623426 hasConcept C181622380 @default.
- W2130623426 hasConcept C186027771 @default.
- W2130623426 hasConcept C19966478 @default.
- W2130623426 hasConcept C2778083465 @default.
- W2130623426 hasConcept C2781014177 @default.
- W2130623426 hasConcept C41008148 @default.
- W2130623426 hasConcept C90509273 @default.
- W2130623426 hasConceptScore W2130623426C10138342 @default.
- W2130623426 hasConceptScore W2130623426C144133560 @default.
- W2130623426 hasConceptScore W2130623426C145424490 @default.
- W2130623426 hasConceptScore W2130623426C154945302 @default.
- W2130623426 hasConceptScore W2130623426C162118730 @default.
- W2130623426 hasConceptScore W2130623426C162324750 @default.
- W2130623426 hasConceptScore W2130623426C163428354 @default.
- W2130623426 hasConceptScore W2130623426C175444787 @default.
- W2130623426 hasConceptScore W2130623426C181622380 @default.
- W2130623426 hasConceptScore W2130623426C186027771 @default.
- W2130623426 hasConceptScore W2130623426C19966478 @default.
- W2130623426 hasConceptScore W2130623426C2778083465 @default.
- W2130623426 hasConceptScore W2130623426C2781014177 @default.
- W2130623426 hasConceptScore W2130623426C41008148 @default.
- W2130623426 hasConceptScore W2130623426C90509273 @default.
- W2130623426 hasIssue "2" @default.
- W2130623426 hasLocation W21306234261 @default.
- W2130623426 hasOpenAccess W2130623426 @default.
- W2130623426 hasPrimaryLocation W21306234261 @default.
- W2130623426 hasRelatedWork W2072739823 @default.
- W2130623426 hasRelatedWork W2167900286 @default.
- W2130623426 hasRelatedWork W2174539897 @default.
- W2130623426 hasRelatedWork W2206824781 @default.
- W2130623426 hasRelatedWork W2741342911 @default.
- W2130623426 hasRelatedWork W3010885279 @default.
- W2130623426 hasRelatedWork W3121498393 @default.
- W2130623426 hasRelatedWork W3123811906 @default.
- W2130623426 hasRelatedWork W3126086081 @default.
- W2130623426 hasRelatedWork W3172688987 @default.
- W2130623426 hasVolume "17" @default.
- W2130623426 isParatext "false" @default.
- W2130623426 isRetracted "false" @default.
- W2130623426 magId "2130623426" @default.
- W2130623426 workType "article" @default.