FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130768085> ?p ?o ?g. }

• W2130768085 endingPage "9" @default.
• W2130768085 startingPage "1" @default.
• W2130768085 abstract "Lactuca serriola L. has traditionally been used in folkloric medicine to manage respiratory, gastrointestinal, and multiple other ailments. The present study was undertaken to explore the effect of methanol extract of L. serriola on isolated rabbit tissue preparations, that is, jejunum, trachea, and aorta in an attempt to validate its folkloric use in traditional medicine for gastrointestinal, respiratory, and vascular ailments. The application of the methanol extract to isolated rabbit jejunum preparations exhibited concentration-dependent spasmogenic effect (0.03 to 3.0 mg/mL), but interestingly further increase in concentration (5.0 mg/mL) resulted in complete spasmolytic effect. The pretreatment of the tissue preparations with atropine (0.1 μ M) caused the suppression of the contractile response. Moreover, the same extract also caused relaxation of K(+)-(80 mM) induced spastic contractions of isolated rabbit jejunum preparations (5.0 mg/mL) and shifted the Ca(++) dose response curves towards right at concentration range of 0.3-1.0 mg/mL. Similarly, the extract application to isolated rabbit tracheal preparations relaxed the carbachol-(1 μ M) induced (0.3-1.0 mg/mL) as well as K(+)-(80 mM) induced contractions (3.0 mg/mL). Furthermore, it relaxed the phenylephrine (1 μ M)-induced contractions in isolated rabbit aorta preparations (3.0 mg/mL) and K(+) (80 mM)-induced contractions (1.0 mg/mL). These effects were found comparable to that of dicyclomine, as an antagonist of muscarinic receptors as well as a possible Ca(++) channel blocker. The previously mentioned findings may partially justify the folkloric use of Lactuca serriola in the management of conditions pertaining to spasm of intestine, bronchioles, and vasculature." @default.
• W2130768085 created "2016-06-24" @default.
• W2130768085 creator A5010899653 @default.
• W2130768085 creator A5036224961 @default.
• W2130768085 creator A5052989493 @default.
• W2130768085 creator A5054386137 @default.
• W2130768085 creator A5057736541 @default.
• W2130768085 creator A5064692439 @default.
• W2130768085 date "2013-01-01" @default.
• W2130768085 modified "2023-10-16" @default.
• W2130768085 title "Pharmacological Effects ofLactuca serriolaL. in Experimental Model of Gastrointestinal, Respiratory, and Vascular Ailments" @default.
• W2130768085 cites W1844605916 @default.
• W2130768085 cites W1966614349 @default.
• W2130768085 cites W1974255629 @default.
• W2130768085 cites W1974331236 @default.
• W2130768085 cites W1974571298 @default.
• W2130768085 cites W1984878744 @default.
• W2130768085 cites W1986464172 @default.
• W2130768085 cites W2043886457 @default.
• W2130768085 cites W2047307338 @default.
• W2130768085 cites W2053547716 @default.
• W2130768085 cites W2057971042 @default.
• W2130768085 cites W2071026308 @default.
• W2130768085 cites W2071960683 @default.
• W2130768085 cites W2084142223 @default.
• W2130768085 cites W2084330407 @default.
• W2130768085 cites W2086346667 @default.
• W2130768085 cites W2090134883 @default.
• W2130768085 cites W2141965419 @default.
• W2130768085 cites W2173520866 @default.
• W2130768085 doi "https://doi.org/10.1155/2013/304394" @default.
• W2130768085 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3638630" @default.
• W2130768085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23662127" @default.
• W2130768085 hasPublicationYear "2013" @default.
• W2130768085 type Work @default.
• W2130768085 sameAs 2130768085 @default.
• W2130768085 citedByCount "24" @default.
• W2130768085 countsByYear W21307680852013 @default.
• W2130768085 countsByYear W21307680852014 @default.
• W2130768085 countsByYear W21307680852015 @default.
• W2130768085 countsByYear W21307680852016 @default.
• W2130768085 countsByYear W21307680852017 @default.
• W2130768085 countsByYear W21307680852019 @default.
• W2130768085 countsByYear W21307680852020 @default.
• W2130768085 countsByYear W21307680852021 @default.
• W2130768085 countsByYear W21307680852022 @default.
• W2130768085 crossrefType "journal-article" @default.
• W2130768085 hasAuthorship W2130768085A5010899653 @default.
• W2130768085 hasAuthorship W2130768085A5036224961 @default.
• W2130768085 hasAuthorship W2130768085A5052989493 @default.
• W2130768085 hasAuthorship W2130768085A5054386137 @default.
• W2130768085 hasAuthorship W2130768085A5057736541 @default.
• W2130768085 hasAuthorship W2130768085A5064692439 @default.
• W2130768085 hasBestOaLocation W21307680851 @default.
• W2130768085 hasConcept C126322002 @default.
• W2130768085 hasConcept C170493617 @default.
• W2130768085 hasConcept C185592680 @default.
• W2130768085 hasConcept C2775859210 @default.
• W2130768085 hasConcept C2776366702 @default.
• W2130768085 hasConcept C2776798904 @default.
• W2130768085 hasConcept C2777952589 @default.
• W2130768085 hasConcept C2778988552 @default.
• W2130768085 hasConcept C33789571 @default.
• W2130768085 hasConcept C42219234 @default.
• W2130768085 hasConcept C534529494 @default.
• W2130768085 hasConcept C556039675 @default.
• W2130768085 hasConcept C71924100 @default.
• W2130768085 hasConcept C84393581 @default.
• W2130768085 hasConcept C98274493 @default.
• W2130768085 hasConceptScore W2130768085C126322002 @default.
• W2130768085 hasConceptScore W2130768085C170493617 @default.
• W2130768085 hasConceptScore W2130768085C185592680 @default.
• W2130768085 hasConceptScore W2130768085C2775859210 @default.
• W2130768085 hasConceptScore W2130768085C2776366702 @default.
• W2130768085 hasConceptScore W2130768085C2776798904 @default.
• W2130768085 hasConceptScore W2130768085C2777952589 @default.
• W2130768085 hasConceptScore W2130768085C2778988552 @default.
• W2130768085 hasConceptScore W2130768085C33789571 @default.
• W2130768085 hasConceptScore W2130768085C42219234 @default.
• W2130768085 hasConceptScore W2130768085C534529494 @default.
• W2130768085 hasConceptScore W2130768085C556039675 @default.
• W2130768085 hasConceptScore W2130768085C71924100 @default.
• W2130768085 hasConceptScore W2130768085C84393581 @default.
• W2130768085 hasConceptScore W2130768085C98274493 @default.
• W2130768085 hasLocation W21307680851 @default.
• W2130768085 hasLocation W21307680852 @default.
• W2130768085 hasLocation W21307680853 @default.
• W2130768085 hasLocation W21307680854 @default.
• W2130768085 hasLocation W21307680855 @default.
• W2130768085 hasOpenAccess W2130768085 @default.
• W2130768085 hasPrimaryLocation W21307680851 @default.
• W2130768085 hasRelatedWork W1951379555 @default.
• W2130768085 hasRelatedWork W1974243904 @default.
• W2130768085 hasRelatedWork W2014138710 @default.
• W2130768085 hasRelatedWork W2130768085 @default.
• W2130768085 hasRelatedWork W2169797714 @default.
• W2130768085 hasRelatedWork W2413725920 @default.
• W2130768085 hasRelatedWork W2519576213 @default.

• next