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• W2130786341 abstract "Abstract A new type of magnetic nanoparticle was synthesized using mesoporous silica MCM‐48 as a template. Magnetite (Fe 3 O 4 ) nanocrystals were incorporated onto the MCM‐48 silica structure by thermal decomposition of iron(III) acetylacetonate. The particle size of these Fe 3 O 4 ‐MCM‐48 composite particles is around 300 nm with an iron oxide content of ca. 20% w/w. Measurements from SQUID magnetometry suggest that these nanoparticles possess superparamagnetic properties similar to those of Fe 3 O 4 nanoparticles. By coating positively charged polyethylenimine on to the surface, DNA can be bound onto the Fe 3 O 4 ‐MCM‐48 nanoparticles. Transfection studies showed that these PEI‐Fe 3 O 4 ‐MCM‐48 particles were highly effective as a transfection reagent, and a 400% increase of transfection efficiency compared with the commercial products was recorded. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res, 2010" @default.
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• W2130786341 date "2009-02-03" @default.
• W2130786341 modified "2023-10-18" @default.
• W2130786341 title "Preparation and characterization of polyethylenimine-coated Fe₃O₄-MCM-48 nanocomposite particles as a novel agent for magnet-assisted transfection" @default.
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• W2130786341 doi "https://doi.org/10.1002/jbm.a.32363" @default.
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