Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130807768> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2130807768 endingPage "45" @default.
- W2130807768 startingPage "39" @default.
- W2130807768 abstract "Normal mice immunized with irradiated Ehrlich ascites tumor (EAT) cells rejected EAT challenge given 2 weeks later but T-cell-deficient [thymectomized lethally irradiated, and bone-marrow-reconstituted (TIR)] mice succumbed. However, when TIR mice were injected i.v. with thymus, lymph node, or spleen cells from normal syngeneic donors immediately following i.p. injection of irradiated EAT cells, they rejected the subsequent tumor challenge. This induction of immunity in TIR mice was shown to be T-cell dependent. Spleen cells from EAT-bearing mice given immediately after irradiated tumor cells were also able to promote rejection of EAT challenge in TIR mice. Spleen cells from EAT-immune mice inhibited EAT growth when admixed with tumor cells prior to i.p. injection into normal recipients, but had no effect on progressive tumor growth when given i.v. immediately after i.p. tumor injection. Immune serum inhibited i.p. EAT growth when given either i.p. or i.v. Whereas inhibition of EAT growth by admixed spleen cells was shown to be T-cell dependent, the activity of the immune serum appeared to be T-cell independent. The data indicate that T lymphocytes are required only in the induction phase of the immune response of mice against EAT, while the efferent phase of the response is accomplished by serum antibodies, perhaps through an interaction with host macrophages." @default.
- W2130807768 created "2016-06-24" @default.
- W2130807768 creator A5051144421 @default.
- W2130807768 date "1979-01-01" @default.
- W2130807768 modified "2023-10-01" @default.
- W2130807768 title "Immune mechanisms in Ehrlich ascites tumor growth in mice" @default.
- W2130807768 cites W1533097576 @default.
- W2130807768 cites W1555967785 @default.
- W2130807768 cites W1568826437 @default.
- W2130807768 cites W1695635197 @default.
- W2130807768 cites W1906834198 @default.
- W2130807768 cites W1971918914 @default.
- W2130807768 cites W1980730317 @default.
- W2130807768 cites W1988170566 @default.
- W2130807768 cites W2022227231 @default.
- W2130807768 cites W2028032566 @default.
- W2130807768 cites W2049341366 @default.
- W2130807768 cites W2051638065 @default.
- W2130807768 cites W2070302891 @default.
- W2130807768 cites W2084682858 @default.
- W2130807768 cites W2111031157 @default.
- W2130807768 cites W2114698677 @default.
- W2130807768 cites W2124263041 @default.
- W2130807768 cites W2406441279 @default.
- W2130807768 doi "https://doi.org/10.1016/0014-2964(79)90203-2" @default.
- W2130807768 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/311288" @default.
- W2130807768 hasPublicationYear "1979" @default.
- W2130807768 type Work @default.
- W2130807768 sameAs 2130807768 @default.
- W2130807768 citedByCount "5" @default.
- W2130807768 crossrefType "journal-article" @default.
- W2130807768 hasAuthorship W2130807768A5051144421 @default.
- W2130807768 hasConcept C126322002 @default.
- W2130807768 hasConcept C134018914 @default.
- W2130807768 hasConcept C1491633281 @default.
- W2130807768 hasConcept C159654299 @default.
- W2130807768 hasConcept C203014093 @default.
- W2130807768 hasConcept C2779341262 @default.
- W2130807768 hasConcept C2780007613 @default.
- W2130807768 hasConcept C2780496750 @default.
- W2130807768 hasConcept C2780635560 @default.
- W2130807768 hasConcept C2780849966 @default.
- W2130807768 hasConcept C2780931953 @default.
- W2130807768 hasConcept C54355233 @default.
- W2130807768 hasConcept C71924100 @default.
- W2130807768 hasConcept C86803240 @default.
- W2130807768 hasConcept C8891405 @default.
- W2130807768 hasConceptScore W2130807768C126322002 @default.
- W2130807768 hasConceptScore W2130807768C134018914 @default.
- W2130807768 hasConceptScore W2130807768C1491633281 @default.
- W2130807768 hasConceptScore W2130807768C159654299 @default.
- W2130807768 hasConceptScore W2130807768C203014093 @default.
- W2130807768 hasConceptScore W2130807768C2779341262 @default.
- W2130807768 hasConceptScore W2130807768C2780007613 @default.
- W2130807768 hasConceptScore W2130807768C2780496750 @default.
- W2130807768 hasConceptScore W2130807768C2780635560 @default.
- W2130807768 hasConceptScore W2130807768C2780849966 @default.
- W2130807768 hasConceptScore W2130807768C2780931953 @default.
- W2130807768 hasConceptScore W2130807768C54355233 @default.
- W2130807768 hasConceptScore W2130807768C71924100 @default.
- W2130807768 hasConceptScore W2130807768C86803240 @default.
- W2130807768 hasConceptScore W2130807768C8891405 @default.
- W2130807768 hasIssue "1" @default.
- W2130807768 hasLocation W21308077681 @default.
- W2130807768 hasLocation W21308077682 @default.
- W2130807768 hasOpenAccess W2130807768 @default.
- W2130807768 hasPrimaryLocation W21308077681 @default.
- W2130807768 hasRelatedWork W1497975460 @default.
- W2130807768 hasRelatedWork W1979348087 @default.
- W2130807768 hasRelatedWork W2004937222 @default.
- W2130807768 hasRelatedWork W2036107469 @default.
- W2130807768 hasRelatedWork W2063167002 @default.
- W2130807768 hasRelatedWork W2081358646 @default.
- W2130807768 hasRelatedWork W2141634946 @default.
- W2130807768 hasRelatedWork W226467497 @default.
- W2130807768 hasRelatedWork W648169728 @default.
- W2130807768 hasRelatedWork W2781693618 @default.
- W2130807768 hasVolume "15" @default.
- W2130807768 isParatext "false" @default.
- W2130807768 isRetracted "false" @default.
- W2130807768 magId "2130807768" @default.
- W2130807768 workType "article" @default.