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- W2130822288 abstract "NO3− supplementation via beetroot juice (BR) augments exercising skeletal muscle blood flow subsequent to its reduction to NO2− then NO. We tested the hypothesis that enhanced vascular control following BR would elevate the skeletal muscle O2 delivery/O2 utilization ratio (microvascular PO2, PmvO2) and raise the PmvO2 during the rest-contractions transition. Rats were administered BR (~0.8 mmol/kg/day, n = 10) or water (control, n = 10) for 5 days. PmvO2 was measured during 180 s of electrically induced (1 Hz) twitch spinotrapezius muscle contractions. There were no changes in resting or contracting steady-state PmvO2. However, BR slowed the PmvO2 fall following contractions onset such that time to reach 63% of the initial PmvO2 fall increased (MRT1; control: 16.8 ± 1.9, BR: 24.4 ± 2.7 s, p < 0.05) and there was a slower relative rate of PmvO2 fall (Δ1PmvO2/τ1; control: 1.9 ± 0.3, BR: 1.2 ± 0.2 mmHg/s, p < 0.05). Despite no significant changes in contracting steady state PmvO2, BR supplementation elevated the O2 driving pressure during the crucial rest-contractions transients thereby providing a potential mechanism by which BR supplementation may improve metabolic control." @default.
- W2130822288 created "2016-06-24" @default.
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- W2130822288 date "2013-07-01" @default.
- W2130822288 modified "2023-09-26" @default.
- W2130822288 title "Effects of nitrate supplementation via beetroot juice on contracting rat skeletal muscle microvascular oxygen pressure dynamics" @default.
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- W2130822288 doi "https://doi.org/10.1016/j.resp.2013.04.001" @default.
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