Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130859575> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2130859575 endingPage "1908" @default.
- W2130859575 startingPage "1903" @default.
- W2130859575 abstract "Abstract IgG-PFC was induced in Epstein-Barr virus-transformed B lymphoblastoid cell lines (LCL) by the addition of allogeneic T cells. T cells involved in the induction of IgG-PFC were shown to belong to the Leu 3a+/2a- T cell subset. Furthermore, partially purified soluble factors obtained from the culture supernatant of PPD-stimulated pleural T cells or PWM-stimulated tonsillar mononuclear cells was shown to induce IgG-PFC in LCL across the major histocompatibility complex barrier. The induction of IgG-PFC was observed only in surface IgG-positive LCL cell populations and was not accompanied by the increase in the number of LCL cells. The factors with such a TRF-like activity were found in two fractions corresponding to the m.w. range of 18,000 to 25,000 (22K fraction) and 28,000 to 38,000 (36K fraction) by gel filtration. Isoelectric focusing of these fractions revealed that TRF-like activity of both 22K and 36K fractions distributed in the pI range of 5.0 to 6.0, and both fractions were found to be devoid of TCGF activity. These results appear to indicate that the factors act on the B cells in terminal stages to trigger final differentiation to Ig-producing cells." @default.
- W2130859575 created "2016-06-24" @default.
- W2130859575 creator A5012931208 @default.
- W2130859575 creator A5030176492 @default.
- W2130859575 creator A5049485656 @default.
- W2130859575 creator A5056051274 @default.
- W2130859575 date "1982-04-01" @default.
- W2130859575 modified "2023-10-18" @default.
- W2130859575 title "Human helper T cell factor(s) (ThF). II. Induction of IgG production in B lymphoblastoid cell lines and identification of T cell-replacing factor- (TRF) like factor(s)." @default.
- W2130859575 doi "https://doi.org/10.4049/jimmunol.128.4.1903" @default.
- W2130859575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6801125" @default.
- W2130859575 hasPublicationYear "1982" @default.
- W2130859575 type Work @default.
- W2130859575 sameAs 2130859575 @default.
- W2130859575 citedByCount "80" @default.
- W2130859575 countsByYear W21308595752012 @default.
- W2130859575 countsByYear W21308595752013 @default.
- W2130859575 countsByYear W21308595752014 @default.
- W2130859575 countsByYear W21308595752016 @default.
- W2130859575 countsByYear W21308595752018 @default.
- W2130859575 countsByYear W21308595752023 @default.
- W2130859575 crossrefType "journal-article" @default.
- W2130859575 hasAuthorship W2130859575A5012931208 @default.
- W2130859575 hasAuthorship W2130859575A5030176492 @default.
- W2130859575 hasAuthorship W2130859575A5049485656 @default.
- W2130859575 hasAuthorship W2130859575A5056051274 @default.
- W2130859575 hasBestOaLocation W21308595751 @default.
- W2130859575 hasConcept C113842279 @default.
- W2130859575 hasConcept C137061746 @default.
- W2130859575 hasConcept C147483822 @default.
- W2130859575 hasConcept C1491633281 @default.
- W2130859575 hasConcept C153911025 @default.
- W2130859575 hasConcept C159654299 @default.
- W2130859575 hasConcept C181199279 @default.
- W2130859575 hasConcept C185592680 @default.
- W2130859575 hasConcept C202751555 @default.
- W2130859575 hasConcept C203014093 @default.
- W2130859575 hasConcept C2776090121 @default.
- W2130859575 hasConcept C2778453870 @default.
- W2130859575 hasConcept C49382859 @default.
- W2130859575 hasConcept C50476208 @default.
- W2130859575 hasConcept C54355233 @default.
- W2130859575 hasConcept C55493867 @default.
- W2130859575 hasConcept C81885089 @default.
- W2130859575 hasConcept C86803240 @default.
- W2130859575 hasConcept C8891405 @default.
- W2130859575 hasConceptScore W2130859575C113842279 @default.
- W2130859575 hasConceptScore W2130859575C137061746 @default.
- W2130859575 hasConceptScore W2130859575C147483822 @default.
- W2130859575 hasConceptScore W2130859575C1491633281 @default.
- W2130859575 hasConceptScore W2130859575C153911025 @default.
- W2130859575 hasConceptScore W2130859575C159654299 @default.
- W2130859575 hasConceptScore W2130859575C181199279 @default.
- W2130859575 hasConceptScore W2130859575C185592680 @default.
- W2130859575 hasConceptScore W2130859575C202751555 @default.
- W2130859575 hasConceptScore W2130859575C203014093 @default.
- W2130859575 hasConceptScore W2130859575C2776090121 @default.
- W2130859575 hasConceptScore W2130859575C2778453870 @default.
- W2130859575 hasConceptScore W2130859575C49382859 @default.
- W2130859575 hasConceptScore W2130859575C50476208 @default.
- W2130859575 hasConceptScore W2130859575C54355233 @default.
- W2130859575 hasConceptScore W2130859575C55493867 @default.
- W2130859575 hasConceptScore W2130859575C81885089 @default.
- W2130859575 hasConceptScore W2130859575C86803240 @default.
- W2130859575 hasConceptScore W2130859575C8891405 @default.
- W2130859575 hasIssue "4" @default.
- W2130859575 hasLocation W21308595751 @default.
- W2130859575 hasLocation W21308595752 @default.
- W2130859575 hasOpenAccess W2130859575 @default.
- W2130859575 hasPrimaryLocation W21308595751 @default.
- W2130859575 hasRelatedWork W2009734913 @default.
- W2130859575 hasRelatedWork W2040191638 @default.
- W2130859575 hasRelatedWork W2043505088 @default.
- W2130859575 hasRelatedWork W2091196627 @default.
- W2130859575 hasRelatedWork W2130859575 @default.
- W2130859575 hasRelatedWork W2158843915 @default.
- W2130859575 hasRelatedWork W2411242516 @default.
- W2130859575 hasRelatedWork W3136622589 @default.
- W2130859575 hasRelatedWork W4244694513 @default.
- W2130859575 hasRelatedWork W86667021 @default.
- W2130859575 hasVolume "128" @default.
- W2130859575 isParatext "false" @default.
- W2130859575 isRetracted "false" @default.
- W2130859575 magId "2130859575" @default.
- W2130859575 workType "article" @default.