FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130882926> ?p ?o ?g. }

• W2130882926 endingPage "562" @default.
• W2130882926 startingPage "553" @default.
• W2130882926 abstract "In a 3-year prospective double blind study, grass pollen allergic patients were allocated to perennial hyposensitization with the timothy major allergens Nos. 19 and 25 (2-component extract) or a 20-component timothy extract. The extracts were biologically standardized and adsorbed to aluminium hydroxide for treatment. Systemic side effects (SSE) had début after 1 1/2–5 h and lasted without treatment 1/2–10 h. Treatment with the 2-component extract showed preponderance of minor SSE (arthralgia, rhinitis, tiredness, headache, conjunctivitis, nausea, flu-like symptoms), but major SSE (urticaria, angioedetma, asthma) were equally distributed between treatment with the two timothy extracts. Major SSE comiplicated the treatment before the first grass pollen season in 33% of the patients vs. only in 3% during the subsequent perentiial therapy, and developed (92%) at high single dose of ≥1,000 biological units. The majority (69%) were later able to reach the same or higher dose without relapse. Most (62%) patients with major SSE were predicted by high nasal sensitivity before treatment. Only 18% of the patients had immediate local skin reactions of ≥2 cm, but delayed local side effects of ≥10 cm were recorded in 70%. Immediate skin reactions did not correlate with delayed skin reactions or with SSE, but delayed local side effects tended towards negative correlation with major SSE. A mean area reduction of 50% of the delayed skin reactions was recorded by repetition of a single dose. Subcutaneous nodules appeared at single doses of ≥5,000 biological units. Only 5% of the patients contracted nodules during initial preseasonal therapy compared with 38% during subsequent perennial dosage. The nodules contained typical benign granulomas, and the frequency in the two groups was proporitonate to the quantity of aluminium in the two extracts." @default.
• W2130882926 created "2016-06-24" @default.
• W2130882926 creator A5041928508 @default.
• W2130882926 date "1982-11-01" @default.
• W2130882926 modified "2023-10-10" @default.
• W2130882926 title "Side Effects during Immunotherapy with Purified Grass Pollen Extracts" @default.
• W2130882926 cites W109138240 @default.
• W2130882926 cites W1539273192 @default.
• W2130882926 cites W1568537730 @default.
• W2130882926 cites W1574022002 @default.
• W2130882926 cites W1754529656 @default.
• W2130882926 cites W1945242940 @default.
• W2130882926 cites W1958319166 @default.
• W2130882926 cites W1976346783 @default.
• W2130882926 cites W1981287345 @default.
• W2130882926 cites W2010599779 @default.
• W2130882926 cites W2039525081 @default.
• W2130882926 cites W2044540551 @default.
• W2130882926 cites W2053255564 @default.
• W2130882926 cites W2055615096 @default.
• W2130882926 cites W2056409361 @default.
• W2130882926 cites W2062345982 @default.
• W2130882926 cites W2062855236 @default.
• W2130882926 cites W2064096200 @default.
• W2130882926 cites W2073105900 @default.
• W2130882926 cites W2074079543 @default.
• W2130882926 cites W2075850391 @default.
• W2130882926 cites W2078343289 @default.
• W2130882926 cites W2083230705 @default.
• W2130882926 cites W2084657503 @default.
• W2130882926 cites W3026766594 @default.
• W2130882926 doi "https://doi.org/10.1111/j.1398-9995.1982.tb02340.x" @default.
• W2130882926 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7181051" @default.
• W2130882926 hasPublicationYear "1982" @default.
• W2130882926 type Work @default.
• W2130882926 sameAs 2130882926 @default.
• W2130882926 citedByCount "53" @default.
• W2130882926 countsByYear W21308829262012 @default.
• W2130882926 countsByYear W21308829262013 @default.
• W2130882926 countsByYear W21308829262014 @default.
• W2130882926 countsByYear W21308829262015 @default.
• W2130882926 countsByYear W21308829262018 @default.
• W2130882926 crossrefType "journal-article" @default.
• W2130882926 hasAuthorship W2130882926A5041928508 @default.
• W2130882926 hasConcept C126322002 @default.
• W2130882926 hasConcept C16005928 @default.
• W2130882926 hasConcept C203014093 @default.
• W2130882926 hasConcept C207480886 @default.
• W2130882926 hasConcept C2776042228 @default.
• W2130882926 hasConcept C2780580376 @default.
• W2130882926 hasConcept C2780852908 @default.
• W2130882926 hasConcept C2908959886 @default.
• W2130882926 hasConcept C71924100 @default.
• W2130882926 hasConcept C90924648 @default.
• W2130882926 hasConceptScore W2130882926C126322002 @default.
• W2130882926 hasConceptScore W2130882926C16005928 @default.
• W2130882926 hasConceptScore W2130882926C203014093 @default.
• W2130882926 hasConceptScore W2130882926C207480886 @default.
• W2130882926 hasConceptScore W2130882926C2776042228 @default.
• W2130882926 hasConceptScore W2130882926C2780580376 @default.
• W2130882926 hasConceptScore W2130882926C2780852908 @default.
• W2130882926 hasConceptScore W2130882926C2908959886 @default.
• W2130882926 hasConceptScore W2130882926C71924100 @default.
• W2130882926 hasConceptScore W2130882926C90924648 @default.
• W2130882926 hasIssue "8" @default.
• W2130882926 hasLocation W21308829261 @default.
• W2130882926 hasLocation W21308829262 @default.
• W2130882926 hasOpenAccess W2130882926 @default.
• W2130882926 hasPrimaryLocation W21308829261 @default.
• W2130882926 hasRelatedWork W148728087 @default.
• W2130882926 hasRelatedWork W1979418062 @default.
• W2130882926 hasRelatedWork W2030053732 @default.
• W2130882926 hasRelatedWork W2035319767 @default.
• W2130882926 hasRelatedWork W2330828714 @default.
• W2130882926 hasRelatedWork W2375265431 @default.
• W2130882926 hasRelatedWork W2376132146 @default.
• W2130882926 hasRelatedWork W2387364079 @default.
• W2130882926 hasRelatedWork W2468000090 @default.
• W2130882926 hasRelatedWork W3142684436 @default.
• W2130882926 hasVolume "37" @default.
• W2130882926 isParatext "false" @default.
• W2130882926 isRetracted "false" @default.
• W2130882926 magId "2130882926" @default.
• W2130882926 workType "article" @default.