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• W2130919690 abstract "How the fetal 'allograft' avoids rejection during pregnancy remains a major unresolved immunological paradox. Recent work has suggested that fetomaternal tolerance is in fact maintained by a number of redundant mechanisms, but their relative importance has remained poorly defined. In this paper, I discuss an emerging controversy regarding the ability of maternal T cells to mediate fetal rejection at a time when they appear to be ignorant of fetal and placental antigens. This paradox within a paradox highlights two major research directions in the field of reproductive immunology that, when ultimately reconciled, promise to give significant insight into mechanisms of impaired fertility and compromised fetal and maternal health." @default.
• W2130919690 created "2016-06-24" @default.
• W2130919690 creator A5063701542 @default.
• W2130919690 date "2010-07-01" @default.
• W2130919690 modified "2023-10-17" @default.
• W2130919690 title "Immune surveillance of the maternal/fetal interface: controversies and implications" @default.
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• W2130919690 doi "https://doi.org/10.1016/j.tem.2010.02.003" @default.
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