FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130955444> ?p ?o ?g. }

• W2130955444 endingPage "G1367" @default.
• W2130955444 startingPage "G1360" @default.
• W2130955444 abstract "A single intraperitoneal injection of endotoxin (40 microg/kg) significantly delayed gastric emptying of a solid nutrient meal. Blockade of nitric oxide synthase (NOS) with 30 mg/kg ip N(G)-nitro-L-arginine methyl ester or 20 mg/kg ip 7-nitroindazole [neuronal NOS (nNOS) inhibitor] significantly delayed gastric emptying in control animals but failed to modify gastric emptying in endotoxin-treated rats. Administration of 2.5, 5, and 10 mg/kg ip N(6)-iminoethyl-L-lysine [inducible NOS (iNOS) inhibitor] had no effect in either experimental group. Indomethacin (5 mg/kg sc), NS-398 (cyclooxygenase-2 inhibitor; 10 mg/kg ip), and dexamethasone (10 mg/kg sc) but not quinacrine (20 mg/kg ip) significantly prevented delay in gastric emptying induced by endotoxin but failed to modify gastric emptying in vehicle-treated animals. Ca(2+)-dependent NOS activity in the antrum pylorus of the stomach was diminished by endotoxin, whereas Ca(2+)-independent NOS activity was not changed. In addition, decreased nNOS mRNA and protein were observed in the antrum pylorus of endotoxin-treated rats. Our results suggest that downregulation of nNOS in the antrum pylorus of the stomach and synthesis of prostaglandins mediate the delay in gastric emptying of a solid nutrient meal induced by endotoxin." @default.
• W2130955444 created "2016-06-24" @default.
• W2130955444 creator A5008592077 @default.
• W2130955444 creator A5011271974 @default.
• W2130955444 creator A5023590155 @default.
• W2130955444 creator A5034763015 @default.
• W2130955444 creator A5043721763 @default.
• W2130955444 creator A5047619169 @default.
• W2130955444 creator A5088077243 @default.
• W2130955444 date "2002-12-01" @default.
• W2130955444 modified "2023-10-17" @default.
• W2130955444 title "Downregulation of nNOS and synthesis of PGs associated with endotoxin-induced delay in gastric emptying" @default.
• W2130955444 cites W1567116148 @default.
• W2130955444 cites W1581327518 @default.
• W2130955444 cites W1942602161 @default.
• W2130955444 cites W1971441412 @default.
• W2130955444 cites W1973535328 @default.
• W2130955444 cites W1978226082 @default.
• W2130955444 cites W1979994394 @default.
• W2130955444 cites W1986138196 @default.
• W2130955444 cites W1989921075 @default.
• W2130955444 cites W1993118553 @default.
• W2130955444 cites W1997364548 @default.
• W2130955444 cites W1997929515 @default.
• W2130955444 cites W2011475822 @default.
• W2130955444 cites W2019465027 @default.
• W2130955444 cites W2022633717 @default.
• W2130955444 cites W2030979666 @default.
• W2130955444 cites W2036781343 @default.
• W2130955444 cites W2037768305 @default.
• W2130955444 cites W2038410983 @default.
• W2130955444 cites W2050636474 @default.
• W2130955444 cites W205477417 @default.
• W2130955444 cites W2079611765 @default.
• W2130955444 cites W2083907136 @default.
• W2130955444 cites W2084900761 @default.
• W2130955444 cites W2088388072 @default.
• W2130955444 cites W2094670345 @default.
• W2130955444 cites W2095647439 @default.
• W2130955444 cites W2114000416 @default.
• W2130955444 cites W2115863905 @default.
• W2130955444 cites W2135511952 @default.
• W2130955444 cites W2142778275 @default.
• W2130955444 cites W2152990613 @default.
• W2130955444 cites W2189455942 @default.
• W2130955444 cites W2239157081 @default.
• W2130955444 cites W2428952612 @default.
• W2130955444 cites W4234401654 @default.
• W2130955444 doi "https://doi.org/10.1152/ajpgi.00168.2002" @default.
• W2130955444 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12433667" @default.
• W2130955444 hasPublicationYear "2002" @default.
• W2130955444 type Work @default.
• W2130955444 sameAs 2130955444 @default.
• W2130955444 citedByCount "53" @default.
• W2130955444 countsByYear W21309554442012 @default.
• W2130955444 countsByYear W21309554442014 @default.
• W2130955444 countsByYear W21309554442016 @default.
• W2130955444 countsByYear W21309554442017 @default.
• W2130955444 countsByYear W21309554442018 @default.
• W2130955444 countsByYear W21309554442019 @default.
• W2130955444 countsByYear W21309554442020 @default.
• W2130955444 countsByYear W21309554442021 @default.
• W2130955444 countsByYear W21309554442022 @default.
• W2130955444 countsByYear W21309554442023 @default.
• W2130955444 crossrefType "journal-article" @default.
• W2130955444 hasAuthorship W2130955444A5008592077 @default.
• W2130955444 hasAuthorship W2130955444A5011271974 @default.
• W2130955444 hasAuthorship W2130955444A5023590155 @default.
• W2130955444 hasAuthorship W2130955444A5034763015 @default.
• W2130955444 hasAuthorship W2130955444A5043721763 @default.
• W2130955444 hasAuthorship W2130955444A5047619169 @default.
• W2130955444 hasAuthorship W2130955444A5088077243 @default.
• W2130955444 hasConcept C104317684 @default.
• W2130955444 hasConcept C126322002 @default.
• W2130955444 hasConcept C127561419 @default.
• W2130955444 hasConcept C131253125 @default.
• W2130955444 hasConcept C134018914 @default.
• W2130955444 hasConcept C185592680 @default.
• W2130955444 hasConcept C2777622882 @default.
• W2130955444 hasConcept C2778012502 @default.
• W2130955444 hasConcept C2779422922 @default.
• W2130955444 hasConcept C2780159080 @default.
• W2130955444 hasConcept C3020479747 @default.
• W2130955444 hasConcept C519581460 @default.
• W2130955444 hasConcept C55493867 @default.
• W2130955444 hasConcept C71924100 @default.
• W2130955444 hasConcept C98274493 @default.
• W2130955444 hasConceptScore W2130955444C104317684 @default.
• W2130955444 hasConceptScore W2130955444C126322002 @default.
• W2130955444 hasConceptScore W2130955444C127561419 @default.
• W2130955444 hasConceptScore W2130955444C131253125 @default.
• W2130955444 hasConceptScore W2130955444C134018914 @default.
• W2130955444 hasConceptScore W2130955444C185592680 @default.
• W2130955444 hasConceptScore W2130955444C2777622882 @default.
• W2130955444 hasConceptScore W2130955444C2778012502 @default.
• W2130955444 hasConceptScore W2130955444C2779422922 @default.
• W2130955444 hasConceptScore W2130955444C2780159080 @default.
• W2130955444 hasConceptScore W2130955444C3020479747 @default.

• next