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• W2130987293 endingPage "111218" @default.
• W2130987293 startingPage "111218" @default.
• W2130987293 abstract "Quantitative phase information obtained by digital holographic microscopy (DHM) can provide new insight into the functions and morphology of single red blood cells (RBCs). Since the functionality of a RBC is related to its three-dimensional (3-D) shape, quantitative 3-D geometric changes induced by storage time can help hematologists realize its optimal functionality period. We quantitatively investigate RBC 3-D geometric changes in the storage lesion using DHM. Our experimental results show that the substantial geometric transformation of the biconcave-shaped RBCs to the spherocyte occurs due to RBC storage lesion. This transformation leads to progressive loss of cell surface area, surface-to-volume ratio, and functionality of RBCs. Furthermore, our quantitative analysis shows that there are significant correlations between chemical and morphological properties of RBCs." @default.
• W2130987293 created "2016-06-24" @default.
• W2130987293 creator A5030247901 @default.
• W2130987293 creator A5088864309 @default.
• W2130987293 date "2015-10-21" @default.
• W2130987293 modified "2023-10-18" @default.
• W2130987293 title "Quantitative investigation of red blood cell three-dimensional geometric and chemical changes in the storage lesion using digital holographic microscopy" @default.
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• W2130987293 doi "https://doi.org/10.1117/1.jbo.20.11.111218" @default.
• W2130987293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26502322" @default.
• W2130987293 hasPublicationYear "2015" @default.
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