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- W2131016853 abstract "Bone scintigraphy allows the diagnostic of many pathologies related to bone through the intravenous administration of a phosphonate bone marker complexed to 99 metastable technetium (99mTc). The instability of these injectable solutions on contact with air can lead to a mixture of pertechnetate VII (99mTcO4-) and technetium IV (99mTcO2-, xH2O), technetium IV being the only derivative to fix bone. A qualitative control of the purity of these solutions proved to be consequently important before administration. We report here the perfecting of a new chromatographic test based on reverse phase high performance thin layer chromatography (HPTLC). This test, simple, rapid and reproductive allows without ambiguity the detection of 99mTcO4-(VII) and 99mTcO2-(IV), xH2O in hydroxymethylene diphosphonate (HMDP) injectable solutions ready to use." @default.
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- W2131016853 date "2006-01-01" @default.
- W2131016853 modified "2023-09-23" @default.
- W2131016853 title "Recherche de 99mTcO4− et de 99mTcO2 – dans les solutions injectables de 99mTc-HMDP par HPTLC en phase inverse" @default.
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