FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2131021098> ?p ?o ?g. }

• W2131021098 abstract "Growth rate In children is reported to have seasonal variability. There are fewer published data regarding seasonal variability while on growth hormone (GH) therapy, and none analyzing growth rate with respect to number of daylight hours.We analyzed 11,587 3-month intervals in 2277 prepubertal children (boys ages 3-14 years, girls ages 3-12 years) with idiopathic GH deficiency from the National Cooperative Growth Study (NCGS) database. All were naive to recombinant human GH (rhGH) therapy. Data were submitted from 31 US study centers. Seasonal variation in height velocity (HV) was assumed to be associated with the average number of daylight hours during the interval of time over which HV was computed. Number of daylight hours was determined from the date of the measurement and the latitude of the study center. Other independent variables evaluated included: height standard deviation score (SDS) at the beginning of the interval, chronologic age at the beginning of the interval, time from the start of rhGH treatment to the middle of the interval, month of the year, body mass index SDS at the beginning of the interval, rhGH dose/kg, mother's height SDS, father's height SDS, and log base 10 of the maximum stimulated GH concentration.All variables examined, except month of the year, correlated significantly with interval HV. There was significant seasonal variability at all latitudes, with summer annualized HV being greater than winter HV. This difference was greatest in the first year of therapy (0.146 cm/yr/daylight hour; P < 0.0001) but persisted in subsequent years (0.121 cm/yr/daylight hr; P < 0.0001). The difference increased with distance from the equator. Growth rate over the year was not different among the latitudes reflected in this North American study.There is seasonal variation in growth of children on rhGH therapy that correlates with number of daylight hours. The effect is modest and is greatest in the first year of therapy. Annual growth rate appears to be equal in children among latitudes covered by the US consistent with exposure to an equal number of daylight hours over the year. The physiologic mechanism behind this seasonal variation is not yet understood." @default.
• W2131021098 created "2016-06-24" @default.
• W2131021098 creator A5002453229 @default.
• W2131021098 creator A5026311248 @default.
• W2131021098 creator A5039672395 @default.
• W2131021098 date "2013-02-02" @default.
• W2131021098 modified "2023-09-27" @default.
• W2131021098 title "Is there “seasonal” variation in height velocity in children treated with growth hormone? Data from the National Cooperative Growth Study" @default.
• W2131021098 cites W1493192705 @default.
• W2131021098 cites W1981538770 @default.
• W2131021098 cites W2030134323 @default.
• W2131021098 cites W2036947131 @default.
• W2131021098 cites W2066280003 @default.
• W2131021098 cites W2080926694 @default.
• W2131021098 cites W2103204018 @default.
• W2131021098 cites W2121550887 @default.
• W2131021098 cites W2320075794 @default.
• W2131021098 cites W4252016832 @default.
• W2131021098 doi "https://doi.org/10.1186/1687-9856-2013-2" @default.
• W2131021098 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3568055" @default.
• W2131021098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23374591" @default.
• W2131021098 hasPublicationYear "2013" @default.
• W2131021098 type Work @default.
• W2131021098 sameAs 2131021098 @default.
• W2131021098 citedByCount "14" @default.
• W2131021098 countsByYear W21310210982014 @default.
• W2131021098 countsByYear W21310210982015 @default.
• W2131021098 countsByYear W21310210982016 @default.
• W2131021098 countsByYear W21310210982019 @default.
• W2131021098 countsByYear W21310210982020 @default.
• W2131021098 countsByYear W21310210982022 @default.
• W2131021098 crossrefType "journal-article" @default.
• W2131021098 hasAuthorship W2131021098A5002453229 @default.
• W2131021098 hasAuthorship W2131021098A5026311248 @default.
• W2131021098 hasAuthorship W2131021098A5039672395 @default.
• W2131021098 hasBestOaLocation W21310210981 @default.
• W2131021098 hasConcept C105795698 @default.
• W2131021098 hasConcept C120665830 @default.
• W2131021098 hasConcept C121332964 @default.
• W2131021098 hasConcept C126322002 @default.
• W2131021098 hasConcept C144024400 @default.
• W2131021098 hasConcept C149277555 @default.
• W2131021098 hasConcept C149923435 @default.
• W2131021098 hasConcept C187212893 @default.
• W2131021098 hasConcept C22679943 @default.
• W2131021098 hasConcept C33923547 @default.
• W2131021098 hasConcept C44249647 @default.
• W2131021098 hasConcept C71924100 @default.
• W2131021098 hasConceptScore W2131021098C105795698 @default.
• W2131021098 hasConceptScore W2131021098C120665830 @default.
• W2131021098 hasConceptScore W2131021098C121332964 @default.
• W2131021098 hasConceptScore W2131021098C126322002 @default.
• W2131021098 hasConceptScore W2131021098C144024400 @default.
• W2131021098 hasConceptScore W2131021098C149277555 @default.
• W2131021098 hasConceptScore W2131021098C149923435 @default.
• W2131021098 hasConceptScore W2131021098C187212893 @default.
• W2131021098 hasConceptScore W2131021098C22679943 @default.
• W2131021098 hasConceptScore W2131021098C33923547 @default.
• W2131021098 hasConceptScore W2131021098C44249647 @default.
• W2131021098 hasConceptScore W2131021098C71924100 @default.
• W2131021098 hasIssue "1" @default.
• W2131021098 hasLocation W21310210981 @default.
• W2131021098 hasLocation W21310210982 @default.
• W2131021098 hasLocation W21310210983 @default.
• W2131021098 hasLocation W21310210984 @default.
• W2131021098 hasOpenAccess W2131021098 @default.
• W2131021098 hasPrimaryLocation W21310210981 @default.
• W2131021098 hasRelatedWork W1990238956 @default.
• W2131021098 hasRelatedWork W1993051078 @default.
• W2131021098 hasRelatedWork W1998053653 @default.
• W2131021098 hasRelatedWork W2037752569 @default.
• W2131021098 hasRelatedWork W2085374921 @default.
• W2131021098 hasRelatedWork W2123033778 @default.
• W2131021098 hasRelatedWork W2125531478 @default.
• W2131021098 hasRelatedWork W2363937938 @default.
• W2131021098 hasRelatedWork W3153556886 @default.
• W2131021098 hasRelatedWork W4231447287 @default.
• W2131021098 hasVolume "2013" @default.
• W2131021098 isParatext "false" @default.
• W2131021098 isRetracted "false" @default.
• W2131021098 magId "2131021098" @default.
• W2131021098 workType "article" @default.