Matches in SemOpenAlex for { <https://semopenalex.org/work/W2131024573> ?p ?o ?g. }
- W2131024573 endingPage "665" @default.
- W2131024573 startingPage "660" @default.
- W2131024573 abstract "During intestinal absorption, dietary polyglutamyl folates are hydrolyzed to monoglutamyl folates by pteroylpolyglutamate hydrolase (folate conjugase). This enzyme is present in the brush border and intracellular fractions of human jejunal mucosa. We compared the activities of brush border and intracellular folate conjugase (BBFC and ICFC), and other mucosal enzymes in the jejunum in continuity and bypassed loop in nine patients who underwent intestinal reconstitution operations 3 to 9 yr after jejunoileal bypass. Control jejunum was obtained from seven obese patients undergoing gastric bypass surgery. Jejunal morphometry showed mucosal hyperplasia with taller villi, larger crypts, and no change in cell size in the jejunum in continuity as compared to control or bypass jejunum. In brush border fractions, specific activities of sucrase and BBFC were significantly greater in the jejunum in continuity than in the control or bypass jejunum. In contrast, the specific activities of the other brush border and intracellular enzymes, including ICFC, were similar in all three segments. This is the first evidence that BBFC, like sucrase, adapts to luminal nutrition. The difference in response of BBFC and ICFC to diet and/or pancreato-biliary secretions provides evidence that these are distinct enzymes which are regulated by different mechanisms." @default.
- W2131024573 created "2016-06-24" @default.
- W2131024573 creator A5037366657 @default.
- W2131024573 creator A5039294202 @default.
- W2131024573 creator A5059222898 @default.
- W2131024573 creator A5084429809 @default.
- W2131024573 date "1985-10-01" @default.
- W2131024573 modified "2023-10-18" @default.
- W2131024573 title "Human intestinal folate conjugase: adaptation after jejunoileal bypass" @default.
- W2131024573 cites W1599947302 @default.
- W2131024573 cites W1659776978 @default.
- W2131024573 cites W1748356065 @default.
- W2131024573 cites W1889857347 @default.
- W2131024573 cites W1912383913 @default.
- W2131024573 cites W1942660206 @default.
- W2131024573 cites W1975899987 @default.
- W2131024573 cites W2001992996 @default.
- W2131024573 cites W2006090683 @default.
- W2131024573 cites W2006805208 @default.
- W2131024573 cites W2009951154 @default.
- W2131024573 cites W2025436566 @default.
- W2131024573 cites W2029584907 @default.
- W2131024573 cites W2031557573 @default.
- W2131024573 cites W2035023874 @default.
- W2131024573 cites W2056375016 @default.
- W2131024573 cites W2075173366 @default.
- W2131024573 cites W2088653619 @default.
- W2131024573 cites W2090892997 @default.
- W2131024573 cites W2093068801 @default.
- W2131024573 cites W2133946461 @default.
- W2131024573 cites W2289395671 @default.
- W2131024573 cites W2339399822 @default.
- W2131024573 cites W2405844035 @default.
- W2131024573 cites W2415266407 @default.
- W2131024573 cites W2428377196 @default.
- W2131024573 cites W4293247451 @default.
- W2131024573 cites W4302341280 @default.
- W2131024573 cites W86248671 @default.
- W2131024573 doi "https://doi.org/10.1093/ajcn/42.4.660" @default.
- W2131024573 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3931452" @default.
- W2131024573 hasPublicationYear "1985" @default.
- W2131024573 type Work @default.
- W2131024573 sameAs 2131024573 @default.
- W2131024573 citedByCount "13" @default.
- W2131024573 crossrefType "journal-article" @default.
- W2131024573 hasAuthorship W2131024573A5037366657 @default.
- W2131024573 hasAuthorship W2131024573A5039294202 @default.
- W2131024573 hasAuthorship W2131024573A5059222898 @default.
- W2131024573 hasAuthorship W2131024573A5084429809 @default.
- W2131024573 hasBestOaLocation W21310245731 @default.
- W2131024573 hasConcept C126322002 @default.
- W2131024573 hasConcept C130316041 @default.
- W2131024573 hasConcept C134018914 @default.
- W2131024573 hasConcept C141071460 @default.
- W2131024573 hasConcept C181199279 @default.
- W2131024573 hasConcept C2776039999 @default.
- W2131024573 hasConcept C2776366702 @default.
- W2131024573 hasConcept C2777226302 @default.
- W2131024573 hasConcept C2778925797 @default.
- W2131024573 hasConcept C3020583074 @default.
- W2131024573 hasConcept C41625074 @default.
- W2131024573 hasConcept C511355011 @default.
- W2131024573 hasConcept C5426402 @default.
- W2131024573 hasConcept C544821477 @default.
- W2131024573 hasConcept C55493867 @default.
- W2131024573 hasConcept C71924100 @default.
- W2131024573 hasConcept C8443397 @default.
- W2131024573 hasConcept C86803240 @default.
- W2131024573 hasConcept C90924648 @default.
- W2131024573 hasConceptScore W2131024573C126322002 @default.
- W2131024573 hasConceptScore W2131024573C130316041 @default.
- W2131024573 hasConceptScore W2131024573C134018914 @default.
- W2131024573 hasConceptScore W2131024573C141071460 @default.
- W2131024573 hasConceptScore W2131024573C181199279 @default.
- W2131024573 hasConceptScore W2131024573C2776039999 @default.
- W2131024573 hasConceptScore W2131024573C2776366702 @default.
- W2131024573 hasConceptScore W2131024573C2777226302 @default.
- W2131024573 hasConceptScore W2131024573C2778925797 @default.
- W2131024573 hasConceptScore W2131024573C3020583074 @default.
- W2131024573 hasConceptScore W2131024573C41625074 @default.
- W2131024573 hasConceptScore W2131024573C511355011 @default.
- W2131024573 hasConceptScore W2131024573C5426402 @default.
- W2131024573 hasConceptScore W2131024573C544821477 @default.
- W2131024573 hasConceptScore W2131024573C55493867 @default.
- W2131024573 hasConceptScore W2131024573C71924100 @default.
- W2131024573 hasConceptScore W2131024573C8443397 @default.
- W2131024573 hasConceptScore W2131024573C86803240 @default.
- W2131024573 hasConceptScore W2131024573C90924648 @default.
- W2131024573 hasIssue "4" @default.
- W2131024573 hasLocation W21310245731 @default.
- W2131024573 hasLocation W21310245732 @default.
- W2131024573 hasOpenAccess W2131024573 @default.
- W2131024573 hasPrimaryLocation W21310245731 @default.
- W2131024573 hasRelatedWork W1965662451 @default.
- W2131024573 hasRelatedWork W1977224356 @default.
- W2131024573 hasRelatedWork W1995184960 @default.
- W2131024573 hasRelatedWork W2031557573 @default.
- W2131024573 hasRelatedWork W2044968436 @default.