Matches in SemOpenAlex for { <https://semopenalex.org/work/W2131089392> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2131089392 endingPage "281" @default.
- W2131089392 startingPage "278" @default.
- W2131089392 abstract "<h3>Background and aims:</h3> In the NICE guideline on childhood urinary tract infection (UTI), it is assumed that the presence or severity of systemic symptoms, especially fever, predicts for renal scarring, and different management is recommended accordingly. We aimed to test this hypothesis by retrospective case note analysis. <h3>Design and subjects:</h3> Notes of children aged under 5 years referred with a first UTI who were assessed for scarring were reviewed. <h3>Main outcome criteria:</h3> Ability to predict for single or multiple scarring from age, sex, fever, vomiting or anorexia or malaise, or need for hospitalisation, within the age bands used by NICE. <h3>Results:</h3> There were 51 (65% girls) scarred and 140 (69% girls) unscarred children. Fever, systemic symptoms and hospitalisation were all commoner among younger children (<6 months vs 6 months–3 years vs >3 years; fever 0.67 vs 0.38 vs 0.38; systemic symptoms 0.78 vs 0.62 vs 0.43; hospitalisation 0.67 vs 0.29 vs 0.19; p<0.001 for all). Having vomiting, anorexia or malaise at presentation correlated weakly with single or multiple renal scarring (R<sup>2</sup> = 0.03; p = 0.02), but sex, age, fever or hospitalisation did not (p>0.5 for all). Sensitivity and specificity data, and plots of proportionate reduction of uncertainty showed that none of these variables was useful for predicting any scarring in children aged <3 years and that they were only weakly predictive in older children. <h3>Conclusions:</h3> Clinical signs at presentation in childhood UTI cannot be used to predict for mild or multiple scarring, and should not be used to guide management. NICE’s recommendation to do so is not justified." @default.
- W2131089392 created "2016-06-24" @default.
- W2131089392 creator A5002254419 @default.
- W2131089392 creator A5046927429 @default.
- W2131089392 creator A5065442614 @default.
- W2131089392 date "2008-11-17" @default.
- W2131089392 modified "2023-09-26" @default.
- W2131089392 title "Do systemic symptoms predict the risk of kidney scarring after urinary tract infection?" @default.
- W2131089392 cites W1152268068 @default.
- W2131089392 cites W1607190847 @default.
- W2131089392 cites W1965443596 @default.
- W2131089392 cites W1972013200 @default.
- W2131089392 cites W1974073249 @default.
- W2131089392 cites W1991481790 @default.
- W2131089392 cites W1992401227 @default.
- W2131089392 cites W2004356084 @default.
- W2131089392 cites W202006725 @default.
- W2131089392 cites W2023533499 @default.
- W2131089392 cites W2036876098 @default.
- W2131089392 cites W2076019861 @default.
- W2131089392 cites W2092937835 @default.
- W2131089392 cites W2095263049 @default.
- W2131089392 cites W2112356865 @default.
- W2131089392 cites W2124436685 @default.
- W2131089392 cites W2153380226 @default.
- W2131089392 cites W2180805840 @default.
- W2131089392 doi "https://doi.org/10.1136/adc.2007.132290" @default.
- W2131089392 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19015216" @default.
- W2131089392 hasPublicationYear "2008" @default.
- W2131089392 type Work @default.
- W2131089392 sameAs 2131089392 @default.
- W2131089392 citedByCount "33" @default.
- W2131089392 countsByYear W21310893922012 @default.
- W2131089392 countsByYear W21310893922013 @default.
- W2131089392 countsByYear W21310893922014 @default.
- W2131089392 countsByYear W21310893922015 @default.
- W2131089392 countsByYear W21310893922016 @default.
- W2131089392 countsByYear W21310893922017 @default.
- W2131089392 countsByYear W21310893922018 @default.
- W2131089392 countsByYear W21310893922020 @default.
- W2131089392 countsByYear W21310893922021 @default.
- W2131089392 countsByYear W21310893922022 @default.
- W2131089392 crossrefType "journal-article" @default.
- W2131089392 hasAuthorship W2131089392A5002254419 @default.
- W2131089392 hasAuthorship W2131089392A5046927429 @default.
- W2131089392 hasAuthorship W2131089392A5065442614 @default.
- W2131089392 hasConcept C126322002 @default.
- W2131089392 hasConcept C142724271 @default.
- W2131089392 hasConcept C187212893 @default.
- W2131089392 hasConcept C199360897 @default.
- W2131089392 hasConcept C2778654693 @default.
- W2131089392 hasConcept C2779256446 @default.
- W2131089392 hasConcept C2779277585 @default.
- W2131089392 hasConcept C2780182762 @default.
- W2131089392 hasConcept C2780852908 @default.
- W2131089392 hasConcept C41008148 @default.
- W2131089392 hasConcept C71924100 @default.
- W2131089392 hasConcept C77411442 @default.
- W2131089392 hasConceptScore W2131089392C126322002 @default.
- W2131089392 hasConceptScore W2131089392C142724271 @default.
- W2131089392 hasConceptScore W2131089392C187212893 @default.
- W2131089392 hasConceptScore W2131089392C199360897 @default.
- W2131089392 hasConceptScore W2131089392C2778654693 @default.
- W2131089392 hasConceptScore W2131089392C2779256446 @default.
- W2131089392 hasConceptScore W2131089392C2779277585 @default.
- W2131089392 hasConceptScore W2131089392C2780182762 @default.
- W2131089392 hasConceptScore W2131089392C2780852908 @default.
- W2131089392 hasConceptScore W2131089392C41008148 @default.
- W2131089392 hasConceptScore W2131089392C71924100 @default.
- W2131089392 hasConceptScore W2131089392C77411442 @default.
- W2131089392 hasIssue "4" @default.
- W2131089392 hasLocation W21310893921 @default.
- W2131089392 hasLocation W21310893922 @default.
- W2131089392 hasOpenAccess W2131089392 @default.
- W2131089392 hasPrimaryLocation W21310893921 @default.
- W2131089392 hasRelatedWork W2070673063 @default.
- W2131089392 hasRelatedWork W2085053297 @default.
- W2131089392 hasRelatedWork W2131089392 @default.
- W2131089392 hasRelatedWork W2324226934 @default.
- W2131089392 hasRelatedWork W2400533830 @default.
- W2131089392 hasRelatedWork W2407566251 @default.
- W2131089392 hasRelatedWork W2408594915 @default.
- W2131089392 hasRelatedWork W2910430287 @default.
- W2131089392 hasRelatedWork W4252299417 @default.
- W2131089392 hasRelatedWork W4298919146 @default.
- W2131089392 hasVolume "94" @default.
- W2131089392 isParatext "false" @default.
- W2131089392 isRetracted "false" @default.
- W2131089392 magId "2131089392" @default.
- W2131089392 workType "article" @default.