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- W2131167236 abstract "ContextQuizalofop-p-ethyl is an often applied, slightly toxic herbicide for which no severe toxicity has been reported in humans.Case presentationWe present the case of a farmer exposed to quizalofop-p-ethyl who presented with obstructive cholestasis. A complete workup disclosed no other cause of liver pathology, but liver biopsy established drug-induced hepatotoxicity. The patient was treated with ursodeoxycholic acid and prednisolone, and was recovered fully 70 days after his exposure to the herbicide. The patient was followed for the next 9 months.ConclusionQuizalofop-p-ethyl can induce a mixed cholestatic/hepatocellular liver injury. We discuss possible mechanisms implicated in liver injury after exposure to quizalofop-p-ethyl.Relevance to clinical or professional practiceIn patients presenting with mixed cholestatic/ hepatocellular liver injury, occupational exposure to quizalofop-p-ethyl in the course of agricultural use should be investigated." @default.
- W2131167236 created "2016-06-24" @default.
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- W2131167236 date "2007-10-01" @default.
- W2131167236 modified "2023-10-18" @default.
- W2131167236 title "Case Report: Mixed Cholestatic/Hepatocellular Liver Injury Induced by the Herbicide Quizalofop-p-ethyl" @default.
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- W2131167236 doi "https://doi.org/10.1289/ehp.9968" @default.
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