Matches in SemOpenAlex for { <https://semopenalex.org/work/W2131231952> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2131231952 endingPage "268" @default.
- W2131231952 startingPage "265" @default.
- W2131231952 abstract "Summary In the 1970s and 1980s, it was observed that rodents could offset excess calories ingested when they were fed a human‐like ‘cafeteria diet’. Although it was erroneously concluded that this so‐called diet‐induced thermogenesis was because of brown adipose tissue (BAT), it led to efforts to test whether variations in brown fat in humans may explain the susceptibility to obesity. However, from evidence on the inability of ephedrine or beta‐3 adrenergic agonists to induce BAT thermogenesis, it was concluded that the thermogenic role of BAT was unimportant in adult humans largely because humans had low numbers of brown adipocytes. Solid evidence on the actual numbers of brown adipocytes in humans was not available. We are now re‐evaluating the role of BAT for the treatment of obesity given the following recent observations (i) studies in nuclear medicine by using PET/CT scanning reveal the presence of BAT in adult humans; and (ii) recent data suggest that a new transcription factor called PDRM16 may control the induction of BAT. These recent discoveries should revamp our effort to target the molecular development of brown adipogenesis in the treatment of obesity." @default.
- W2131231952 created "2016-06-24" @default.
- W2131231952 creator A5034783079 @default.
- W2131231952 creator A5069618649 @default.
- W2131231952 date "2009-04-24" @default.
- W2131231952 modified "2023-10-15" @default.
- W2131231952 title "Have we entered the brown adipose tissue renaissance?" @default.
- W2131231952 cites W1974418613 @default.
- W2131231952 cites W1981525131 @default.
- W2131231952 cites W2025356026 @default.
- W2131231952 cites W2034958364 @default.
- W2131231952 cites W2045205233 @default.
- W2131231952 cites W2046003585 @default.
- W2131231952 cites W2051516736 @default.
- W2131231952 cites W2061505650 @default.
- W2131231952 cites W2091424052 @default.
- W2131231952 cites W2098457930 @default.
- W2131231952 cites W2104827888 @default.
- W2131231952 cites W2179212920 @default.
- W2131231952 cites W3157521036 @default.
- W2131231952 cites W4376849766 @default.
- W2131231952 cites W94016247 @default.
- W2131231952 doi "https://doi.org/10.1111/j.1467-789x.2008.00559.x" @default.
- W2131231952 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3960797" @default.
- W2131231952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19175509" @default.
- W2131231952 hasPublicationYear "2009" @default.
- W2131231952 type Work @default.
- W2131231952 sameAs 2131231952 @default.
- W2131231952 citedByCount "63" @default.
- W2131231952 countsByYear W21312319522012 @default.
- W2131231952 countsByYear W21312319522013 @default.
- W2131231952 countsByYear W21312319522014 @default.
- W2131231952 countsByYear W21312319522015 @default.
- W2131231952 countsByYear W21312319522016 @default.
- W2131231952 countsByYear W21312319522017 @default.
- W2131231952 countsByYear W21312319522018 @default.
- W2131231952 countsByYear W21312319522020 @default.
- W2131231952 countsByYear W21312319522021 @default.
- W2131231952 crossrefType "journal-article" @default.
- W2131231952 hasAuthorship W2131231952A5034783079 @default.
- W2131231952 hasAuthorship W2131231952A5069618649 @default.
- W2131231952 hasBestOaLocation W21312319522 @default.
- W2131231952 hasConcept C122927707 @default.
- W2131231952 hasConcept C126322002 @default.
- W2131231952 hasConcept C134018914 @default.
- W2131231952 hasConcept C142724271 @default.
- W2131231952 hasConcept C143128242 @default.
- W2131231952 hasConcept C151279926 @default.
- W2131231952 hasConcept C171089720 @default.
- W2131231952 hasConcept C2780509477 @default.
- W2131231952 hasConcept C2780642333 @default.
- W2131231952 hasConcept C40438245 @default.
- W2131231952 hasConcept C42407357 @default.
- W2131231952 hasConcept C511355011 @default.
- W2131231952 hasConcept C71924100 @default.
- W2131231952 hasConcept C86803240 @default.
- W2131231952 hasConceptScore W2131231952C122927707 @default.
- W2131231952 hasConceptScore W2131231952C126322002 @default.
- W2131231952 hasConceptScore W2131231952C134018914 @default.
- W2131231952 hasConceptScore W2131231952C142724271 @default.
- W2131231952 hasConceptScore W2131231952C143128242 @default.
- W2131231952 hasConceptScore W2131231952C151279926 @default.
- W2131231952 hasConceptScore W2131231952C171089720 @default.
- W2131231952 hasConceptScore W2131231952C2780509477 @default.
- W2131231952 hasConceptScore W2131231952C2780642333 @default.
- W2131231952 hasConceptScore W2131231952C40438245 @default.
- W2131231952 hasConceptScore W2131231952C42407357 @default.
- W2131231952 hasConceptScore W2131231952C511355011 @default.
- W2131231952 hasConceptScore W2131231952C71924100 @default.
- W2131231952 hasConceptScore W2131231952C86803240 @default.
- W2131231952 hasIssue "3" @default.
- W2131231952 hasLocation W21312319521 @default.
- W2131231952 hasLocation W21312319522 @default.
- W2131231952 hasLocation W21312319523 @default.
- W2131231952 hasLocation W21312319524 @default.
- W2131231952 hasOpenAccess W2131231952 @default.
- W2131231952 hasPrimaryLocation W21312319521 @default.
- W2131231952 hasRelatedWork W1488310572 @default.
- W2131231952 hasRelatedWork W1501744089 @default.
- W2131231952 hasRelatedWork W2015346306 @default.
- W2131231952 hasRelatedWork W2050132057 @default.
- W2131231952 hasRelatedWork W2073765502 @default.
- W2131231952 hasRelatedWork W2131231952 @default.
- W2131231952 hasRelatedWork W2201626021 @default.
- W2131231952 hasRelatedWork W2409660031 @default.
- W2131231952 hasRelatedWork W2531565618 @default.
- W2131231952 hasRelatedWork W2763780577 @default.
- W2131231952 hasVolume "10" @default.
- W2131231952 isParatext "false" @default.
- W2131231952 isRetracted "false" @default.
- W2131231952 magId "2131231952" @default.
- W2131231952 workType "article" @default.