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- W2131245700 abstract "In eukaryotic cells, RNA polymerase II (RNA pol II) transcription and pre-mRNA processing are coordinated events. We have addressed how individual components of the transcription and pre-mRNA processing machinery are organized during mitosis and subsequently recruited into the newly formed daughter nuclei. Interestingly, localization studies of numerous RNA pol II transcription and pre-mRNA processing factors revealed a nonrandom and sequential entry of these factors into daughter nuclei after nuclear envelope/lamina formation. The initiation competent form of RNA pol II and general transcription factors appeared in the daughter nuclei simultaneously, but prior to pre-mRNA processing factors, whereas the elongation competent form of RNA pol II was detected even later. The differential entry of these factors rules out the possibility that they are transported as a unitary complex. Telophase nuclei were competent for transcription and pre-mRNA splicing concomitant with the initial entry of the respective factors. In addition, our results revealed a low turnover rate of transcription and pre-mRNA splicing factors during mitosis. We provide evidence to support a model in which the entry of the RNA pol II gene expression machinery into newly forming daughter nuclei is a staged and ordered process." @default.
- W2131245700 created "2016-06-24" @default.
- W2131245700 creator A5029341485 @default.
- W2131245700 creator A5062269074 @default.
- W2131245700 creator A5079751903 @default.
- W2131245700 creator A5090810201 @default.
- W2131245700 date "2003-03-01" @default.
- W2131245700 modified "2023-10-10" @default.
- W2131245700 title "Sequential Entry of Components of Gene Expression Machinery into Daughter Nuclei" @default.
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- W2131245700 cites W1497153204 @default.
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- W2131245700 cites W1531644439 @default.
- W2131245700 cites W1532197406 @default.
- W2131245700 cites W1549536215 @default.
- W2131245700 cites W1581840018 @default.
- W2131245700 cites W1895074262 @default.
- W2131245700 cites W1937235003 @default.
- W2131245700 cites W1954289976 @default.
- W2131245700 cites W1964629933 @default.
- W2131245700 cites W1964834936 @default.
- W2131245700 cites W1965619464 @default.
- W2131245700 cites W1968872346 @default.
- W2131245700 cites W1968978297 @default.
- W2131245700 cites W1973052124 @default.
- W2131245700 cites W1976226375 @default.
- W2131245700 cites W1978827094 @default.
- W2131245700 cites W1979906352 @default.
- W2131245700 cites W1981176424 @default.
- W2131245700 cites W1988904557 @default.
- W2131245700 cites W1998475589 @default.
- W2131245700 cites W1999037332 @default.
- W2131245700 cites W2001208409 @default.
- W2131245700 cites W2006931677 @default.
- W2131245700 cites W2011926249 @default.
- W2131245700 cites W2016385127 @default.
- W2131245700 cites W2017050402 @default.
- W2131245700 cites W2024839121 @default.
- W2131245700 cites W2024993060 @default.
- W2131245700 cites W2029047331 @default.
- W2131245700 cites W2040539493 @default.
- W2131245700 cites W2051037608 @default.
- W2131245700 cites W2053783765 @default.
- W2131245700 cites W2054084236 @default.
- W2131245700 cites W2058144279 @default.
- W2131245700 cites W2060554618 @default.
- W2131245700 cites W2067099248 @default.
- W2131245700 cites W2072798319 @default.
- W2131245700 cites W2080568795 @default.
- W2131245700 cites W2082210185 @default.
- W2131245700 cites W2091955128 @default.
- W2131245700 cites W2093139273 @default.
- W2131245700 cites W2094134169 @default.
- W2131245700 cites W2099856732 @default.
- W2131245700 cites W2099878097 @default.
- W2131245700 cites W2100649212 @default.
- W2131245700 cites W2104531065 @default.
- W2131245700 cites W2104659614 @default.
- W2131245700 cites W2105495356 @default.
- W2131245700 cites W2107521525 @default.
- W2131245700 cites W2107594198 @default.
- W2131245700 cites W2107959123 @default.
- W2131245700 cites W2110096464 @default.
- W2131245700 cites W2110809853 @default.
- W2131245700 cites W2111013687 @default.
- W2131245700 cites W2116008573 @default.
- W2131245700 cites W2116764585 @default.
- W2131245700 cites W2116766341 @default.
- W2131245700 cites W2118629290 @default.
- W2131245700 cites W2119828465 @default.
- W2131245700 cites W2123892444 @default.
- W2131245700 cites W2138165292 @default.
- W2131245700 cites W2139334062 @default.
- W2131245700 cites W2142780571 @default.
- W2131245700 cites W2142939796 @default.
- W2131245700 cites W2146404878 @default.
- W2131245700 cites W2151298994 @default.
- W2131245700 cites W2152464785 @default.
- W2131245700 cites W2153161471 @default.
- W2131245700 cites W2153827965 @default.
- W2131245700 cites W2154153541 @default.
- W2131245700 cites W2155127403 @default.
- W2131245700 cites W2156403775 @default.
- W2131245700 cites W2167931447 @default.
- W2131245700 cites W2168120693 @default.
- W2131245700 cites W2171171901 @default.
- W2131245700 cites W2244187993 @default.
- W2131245700 cites W2258126634 @default.
- W2131245700 cites W2437085630 @default.
- W2131245700 cites W4213068446 @default.
- W2131245700 doi "https://doi.org/10.1091/mbc.e02-10-0669" @default.
- W2131245700 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/151578" @default.
- W2131245700 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12631722" @default.
- W2131245700 hasPublicationYear "2003" @default.
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