FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2131401114> ?p ?o ?g. }

• W2131401114 endingPage "35" @default.
• W2131401114 startingPage "613" @default.
• W2131401114 abstract "This study gains insight on the nature of flow blockage effects of small guidewire catheter sensors in measuring mean trans-stenotic pressure gradients Deltap across significant coronary artery stenoses. Detailed pulsatile hemodynamic computations were made in conjunction with previously reported clinical data in a group of patients with clinically significant coronary lesions before angioplasty. Results of this study ascertain changes in hemodynamic conditions due to the insertion of a guidewire catheter (di=0.46 mm) across the lesions used to directly determine the mean pressure gradient (Deltap) and fall in distal mean coronary pressure (pr). For the 32 patient group of Wilson et al. [1988] (minimal lesion diameter dm=0.95 mm; 90% mean area stenosis; proximal measured coronary flow reserve (CFR) of 2.3 in the abnormal range) the diameter ratio of guidewire catheter to minimal lesion was 0.48, causing a tighter artifactual mean area stenosis of 92.1%. The results of the computations indicated a significant shift in the Deltap-Q relation due to guidewire induced increases in flow resistances (R=Deltap/Q) of 110% for hyperemic flow, a 35% blockage in hyperemic flow (Qh) and a phase shift of the coronary flow waveform to systolic predominance. These alterations in flow resulted in a fall in distal mean coronary pressure (at lower mean flow rates) below the patho-physiological range of prh approximately 55 mmHg, which is known to cause ischemia in the subendocardium (Brown et al. [1984]) and coincides with symptomatic angina. Transient wall shear stress levels in the narrow throat region (with flow blockage) were of the order of levels during hyperemic conditions for patho-physiological flow. In the separated flow region along the distal vessel wall, vortical flow cells formed periodically during the systolic phase when instantaneous Reynolds numbers Ree(t) exceeded about 110. For patho-physiological flow without the presence of the guidewire these vortical flow cells were much stronger than in the more viscous flow regime with the guidewire present. The non-dimensional pressure data given in tabular form may be useful in interpretation of guidewire measurements done clinically for lesions of similar geometry and severity." @default.
• W2131401114 created "2016-06-24" @default.
• W2131401114 creator A5014785844 @default.
• W2131401114 creator A5044021914 @default.
• W2131401114 creator A5085385488 @default.
• W2131401114 date "2003-01-01" @default.
• W2131401114 modified "2023-09-23" @default.
• W2131401114 title "Effects of diagnostic guidewire catheter presence on translesional hemodynamic measurements across significant coronary artery stenoses." @default.
• W2131401114 cites W1457337077 @default.
• W2131401114 cites W1667584244 @default.
• W2131401114 cites W1965224363 @default.
• W2131401114 cites W1967159306 @default.
• W2131401114 cites W1970959909 @default.
• W2131401114 cites W1977922523 @default.
• W2131401114 cites W1980278241 @default.
• W2131401114 cites W1983387638 @default.
• W2131401114 cites W1988120249 @default.
• W2131401114 cites W1989456091 @default.
• W2131401114 cites W1994374856 @default.
• W2131401114 cites W1996873499 @default.
• W2131401114 cites W2005271342 @default.
• W2131401114 cites W2022215142 @default.
• W2131401114 cites W2030133216 @default.
• W2131401114 cites W2031351701 @default.
• W2131401114 cites W2040256795 @default.
• W2131401114 cites W2042533377 @default.
• W2131401114 cites W2046037710 @default.
• W2131401114 cites W2050620855 @default.
• W2131401114 cites W2067594204 @default.
• W2131401114 cites W2070972264 @default.
• W2131401114 cites W2074422867 @default.
• W2131401114 cites W2086887798 @default.
• W2131401114 cites W2087655117 @default.
• W2131401114 cites W2104202075 @default.
• W2131401114 cites W2127061804 @default.
• W2131401114 cites W2133492419 @default.
• W2131401114 cites W2317358310 @default.
• W2131401114 cites W2416284640 @default.
• W2131401114 cites W56510967 @default.
• W2131401114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14610312" @default.
• W2131401114 hasPublicationYear "2003" @default.
• W2131401114 type Work @default.
• W2131401114 sameAs 2131401114 @default.
• W2131401114 citedByCount "7" @default.
• W2131401114 countsByYear W21314011142012 @default.
• W2131401114 countsByYear W21314011142013 @default.
• W2131401114 countsByYear W21314011142014 @default.
• W2131401114 countsByYear W21314011142015 @default.
• W2131401114 crossrefType "journal-article" @default.
• W2131401114 hasAuthorship W2131401114A5014785844 @default.
• W2131401114 hasAuthorship W2131401114A5044021914 @default.
• W2131401114 hasAuthorship W2131401114A5085385488 @default.
• W2131401114 hasConcept C126322002 @default.
• W2131401114 hasConcept C126838900 @default.
• W2131401114 hasConcept C158846371 @default.
• W2131401114 hasConcept C164705383 @default.
• W2131401114 hasConcept C178853913 @default.
• W2131401114 hasConcept C2776820930 @default.
• W2131401114 hasConcept C2777987666 @default.
• W2131401114 hasConcept C2778707443 @default.
• W2131401114 hasConcept C2780007028 @default.
• W2131401114 hasConcept C2780326628 @default.
• W2131401114 hasConcept C2781267111 @default.
• W2131401114 hasConcept C3019004856 @default.
• W2131401114 hasConcept C500558357 @default.
• W2131401114 hasConcept C71924100 @default.
• W2131401114 hasConcept C79191276 @default.
• W2131401114 hasConceptScore W2131401114C126322002 @default.
• W2131401114 hasConceptScore W2131401114C126838900 @default.
• W2131401114 hasConceptScore W2131401114C158846371 @default.
• W2131401114 hasConceptScore W2131401114C164705383 @default.
• W2131401114 hasConceptScore W2131401114C178853913 @default.
• W2131401114 hasConceptScore W2131401114C2776820930 @default.
• W2131401114 hasConceptScore W2131401114C2777987666 @default.
• W2131401114 hasConceptScore W2131401114C2778707443 @default.
• W2131401114 hasConceptScore W2131401114C2780007028 @default.
• W2131401114 hasConceptScore W2131401114C2780326628 @default.
• W2131401114 hasConceptScore W2131401114C2781267111 @default.
• W2131401114 hasConceptScore W2131401114C3019004856 @default.
• W2131401114 hasConceptScore W2131401114C500558357 @default.
• W2131401114 hasConceptScore W2131401114C71924100 @default.
• W2131401114 hasConceptScore W2131401114C79191276 @default.
• W2131401114 hasIssue "6" @default.
• W2131401114 hasLocation W21314011141 @default.
• W2131401114 hasOpenAccess W2131401114 @default.
• W2131401114 hasPrimaryLocation W21314011141 @default.
• W2131401114 hasRelatedWork W1181580204 @default.
• W2131401114 hasRelatedWork W1966549889 @default.
• W2131401114 hasRelatedWork W2020650088 @default.
• W2131401114 hasRelatedWork W2105419762 @default.
• W2131401114 hasRelatedWork W2150748964 @default.
• W2131401114 hasRelatedWork W2171611113 @default.
• W2131401114 hasRelatedWork W2372827368 @default.
• W2131401114 hasRelatedWork W2413116931 @default.
• W2131401114 hasRelatedWork W4236405292 @default.
• W2131401114 hasRelatedWork W2097927076 @default.
• W2131401114 hasVolume "40" @default.
• W2131401114 isParatext "false" @default.

• next