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- W2131432405 abstract "Focal and segmental glomerulosclerosis (FSGS) is a histological entity commonly found in children and adults with steroid-resistant nephrotic syndrome (SRNS), with a 10-year renal survival rate in the 40–60% range [1–3]. FSGS has diverse aetiologies, among which genetic, infectious, toxic and inflammatory factors have been identified. In the last few years, significant advances have been made in the identification of genes involved in the development of familial forms of FSGS, thereby revealing molecules which play a central role in podocyte function. Determination of the appropriate genetic diagnosis is crucial, as it allows accurate counselling to be provided for the patients and their families, particularly on the risk of disease transmission." @default.
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- W2131432405 date "2010-06-08" @default.
- W2131432405 modified "2023-10-17" @default.
- W2131432405 title "What is the risk that I will transmit nephrotic syndrome to my children, Doctor?" @default.
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- W2131432405 doi "https://doi.org/10.1093/ndtplus/sfq095" @default.
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