FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2131472785> ?p ?o ?g. }

• W2131472785 endingPage "9" @default.
• W2131472785 startingPage "631" @default.
• W2131472785 abstract "Oral osmotic delivery systems containing polyethylene oxide (PEO, a water-swellable polymer) were designed and the release of cyclobenzaprine hydrochloride (model drug) from the devices was investigated. The systems consisted of model drug, mannitol (osmotic agent), and increasing amounts of PEO surrounded by a semipermeable membrane drilled with a delivery orifice. There was a decrease in drug release rate with PEO in the core. This may be due to solubility-modulating properties of the polymer. Visual inspection of the devices with PEO showed significant swelling during dissolution testing. Swelling (internal pressure) may influence water inhibition rate into the core and subsequently drug release rate. The release rates were a function of membrane thickness. The release rates were independent of orifice size (range of 150-510 microns diameter) and hydrodynamic conditions for the devices. This would be advantageous in the delivery of drugs in man." @default.
• W2131472785 created "2016-06-24" @default.
• W2131472785 creator A5037278437 @default.
• W2131472785 creator A5070638962 @default.
• W2131472785 date "2002-07-01" @default.
• W2131472785 modified "2023-09-23" @default.
• W2131472785 title "Investigation of cyclobenzaprine hydrochloride release from oral osmotic delivery systems containing a water-swellable polymer." @default.
• W2131472785 cites W142178583 @default.
• W2131472785 cites W1568003459 @default.
• W2131472785 cites W1997615096 @default.
• W2131472785 cites W2004171816 @default.
• W2131472785 cites W2024610761 @default.
• W2131472785 cites W2059210031 @default.
• W2131472785 cites W2062374144 @default.
• W2131472785 cites W2077502175 @default.
• W2131472785 cites W2139101935 @default.
• W2131472785 cites W2147300912 @default.
• W2131472785 doi "https://doi.org/10.1081/ddc-120003854" @default.
• W2131472785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12149955" @default.
• W2131472785 hasPublicationYear "2002" @default.
• W2131472785 type Work @default.
• W2131472785 sameAs 2131472785 @default.
• W2131472785 citedByCount "12" @default.
• W2131472785 countsByYear W21314727852012 @default.
• W2131472785 countsByYear W21314727852013 @default.
• W2131472785 crossrefType "journal-article" @default.
• W2131472785 hasAuthorship W2131472785A5037278437 @default.
• W2131472785 hasAuthorship W2131472785A5070638962 @default.
• W2131472785 hasConcept C100701293 @default.
• W2131472785 hasConcept C105702510 @default.
• W2131472785 hasConcept C107511713 @default.
• W2131472785 hasConcept C127413603 @default.
• W2131472785 hasConcept C155574463 @default.
• W2131472785 hasConcept C159985019 @default.
• W2131472785 hasConcept C178790620 @default.
• W2131472785 hasConcept C185592680 @default.
• W2131472785 hasConcept C192562407 @default.
• W2131472785 hasConcept C194242075 @default.
• W2131472785 hasConcept C2778409621 @default.
• W2131472785 hasConcept C2778445172 @default.
• W2131472785 hasConcept C2778540859 @default.
• W2131472785 hasConcept C2779820397 @default.
• W2131472785 hasConcept C41625074 @default.
• W2131472785 hasConcept C42360764 @default.
• W2131472785 hasConcept C43617362 @default.
• W2131472785 hasConcept C521977710 @default.
• W2131472785 hasConcept C55493867 @default.
• W2131472785 hasConcept C59822182 @default.
• W2131472785 hasConcept C71924100 @default.
• W2131472785 hasConcept C86803240 @default.
• W2131472785 hasConcept C88380143 @default.
• W2131472785 hasConcept C9603476 @default.
• W2131472785 hasConceptScore W2131472785C100701293 @default.
• W2131472785 hasConceptScore W2131472785C105702510 @default.
• W2131472785 hasConceptScore W2131472785C107511713 @default.
• W2131472785 hasConceptScore W2131472785C127413603 @default.
• W2131472785 hasConceptScore W2131472785C155574463 @default.
• W2131472785 hasConceptScore W2131472785C159985019 @default.
• W2131472785 hasConceptScore W2131472785C178790620 @default.
• W2131472785 hasConceptScore W2131472785C185592680 @default.
• W2131472785 hasConceptScore W2131472785C192562407 @default.
• W2131472785 hasConceptScore W2131472785C194242075 @default.
• W2131472785 hasConceptScore W2131472785C2778409621 @default.
• W2131472785 hasConceptScore W2131472785C2778445172 @default.
• W2131472785 hasConceptScore W2131472785C2778540859 @default.
• W2131472785 hasConceptScore W2131472785C2779820397 @default.
• W2131472785 hasConceptScore W2131472785C41625074 @default.
• W2131472785 hasConceptScore W2131472785C42360764 @default.
• W2131472785 hasConceptScore W2131472785C43617362 @default.
• W2131472785 hasConceptScore W2131472785C521977710 @default.
• W2131472785 hasConceptScore W2131472785C55493867 @default.
• W2131472785 hasConceptScore W2131472785C59822182 @default.
• W2131472785 hasConceptScore W2131472785C71924100 @default.
• W2131472785 hasConceptScore W2131472785C86803240 @default.
• W2131472785 hasConceptScore W2131472785C88380143 @default.
• W2131472785 hasConceptScore W2131472785C9603476 @default.
• W2131472785 hasIssue "6" @default.
• W2131472785 hasLocation W21314727851 @default.
• W2131472785 hasLocation W21314727852 @default.
• W2131472785 hasOpenAccess W2131472785 @default.
• W2131472785 hasPrimaryLocation W21314727851 @default.
• W2131472785 hasRelatedWork W1965900222 @default.
• W2131472785 hasRelatedWork W1991681807 @default.
• W2131472785 hasRelatedWork W2006514913 @default.
• W2131472785 hasRelatedWork W2007065397 @default.
• W2131472785 hasRelatedWork W2010921896 @default.
• W2131472785 hasRelatedWork W2020005753 @default.
• W2131472785 hasRelatedWork W2033132971 @default.
• W2131472785 hasRelatedWork W2044109296 @default.
• W2131472785 hasRelatedWork W2065203743 @default.
• W2131472785 hasRelatedWork W2079407952 @default.
• W2131472785 hasRelatedWork W2132193279 @default.
• W2131472785 hasRelatedWork W2133194106 @default.
• W2131472785 hasRelatedWork W2140574081 @default.
• W2131472785 hasRelatedWork W2147300912 @default.
• W2131472785 hasRelatedWork W2153727051 @default.
• W2131472785 hasRelatedWork W2167623132 @default.
• W2131472785 hasRelatedWork W2316182176 @default.

• next