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- W2131478658 abstract "In this study, we developed a mouse model of skin infection to test the association between expression of immunoglobulin-binding proteins by and infectivity of group A streptococci. Group A streptococci capable of crossing tissue barriers and establishing a lethal systemic infection in mice showed a higher level of immunoglobulin-binding protein expression. The group A streptococci recovered from the spleen of a mouse that died following a skin infection were found to be more virulent when injected into the skin of naive mice. Together, these results suggest that immunoglobulin-binding protein expression by group A streptococci correlates with their ability to establish invasive skin infections." @default.
- W2131478658 created "2016-06-24" @default.
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- W2131478658 date "1993-04-01" @default.
- W2131478658 modified "2023-10-16" @default.
- W2131478658 title "Association between expression of immunoglobulin G-binding proteins by group A streptococci and virulence in a mouse skin infection model" @default.
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- W2131478658 doi "https://doi.org/10.1128/iai.61.4.1378-1384.1993" @default.
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