FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2131524336> ?p ?o ?g. }

• W2131524336 endingPage "1461" @default.
• W2131524336 startingPage "1452" @default.
• W2131524336 abstract "This meta-analysis investigated how the supportive care provided in antidepressant clinical trials for late-life depression influences response and drop-out rates.Medline, PsycINFO, and PubMed were searched to identify trials contrasting antidepressants with placebo or active comparator in outpatients aged at least 60 years with major depressive disorder. Hierarchical linear modeling was used to determine whether treatment assignment (medication versus placebo), study type (placebo-controlled or comparator), study duration, and the number of study visits affected response and attrition rates.In the response rate analysis, a significant interaction was found between study visits and treatment assignment (odds ratio [OR]: 0.89, t = -2.186, df = 36, p = 0.035), such that each additional visit over the grand mean for the sample increased average placebo response by 2.5% while not significantly affecting medication response. Controlling for other variables, the effect of this interaction was to dramatically decrease average medication versus placebo differences in trials having greater numbers of study visits. Neither the number of study visits (OR: 0.96, t = -0.468, df = 14, p = 0.646) nor the treatment × visits interaction (OR: 1.03, t = 0.463, df = 35, p = 0.645) influenced drop-out rates.Increased supportive care in the form of clinic visits leads to greater placebo but not antidepressant medication response in clinical trials for late-life depression. Less frequent visit schedules may increase average medication-placebo differences in randomized controlled trials without appreciably increasing drop-out rates." @default.
• W2131524336 created "2016-06-24" @default.
• W2131524336 creator A5001249292 @default.
• W2131524336 creator A5015443550 @default.
• W2131524336 creator A5028614908 @default.
• W2131524336 creator A5035009865 @default.
• W2131524336 creator A5057041995 @default.
• W2131524336 date "2014-12-01" @default.
• W2131524336 modified "2023-09-26" @default.
• W2131524336 title "Clinic Visits in Late-Life Depression Trials: Effects on Signal Detection and Therapeutic Outcome" @default.
• W2131524336 cites W1970985627 @default.
• W2131524336 cites W1977304884 @default.
• W2131524336 cites W1979782653 @default.
• W2131524336 cites W1989302385 @default.
• W2131524336 cites W1989468762 @default.
• W2131524336 cites W1994862345 @default.
• W2131524336 cites W1995140834 @default.
• W2131524336 cites W2018434620 @default.
• W2131524336 cites W2018545462 @default.
• W2131524336 cites W2018819062 @default.
• W2131524336 cites W2029846038 @default.
• W2131524336 cites W2030116324 @default.
• W2131524336 cites W2044095917 @default.
• W2131524336 cites W2045775503 @default.
• W2131524336 cites W2049217505 @default.
• W2131524336 cites W2056065496 @default.
• W2131524336 cites W2067495470 @default.
• W2131524336 cites W2077496996 @default.
• W2131524336 cites W2079009773 @default.
• W2131524336 cites W2084528484 @default.
• W2131524336 cites W2085644156 @default.
• W2131524336 cites W2110440425 @default.
• W2131524336 cites W2114613490 @default.
• W2131524336 cites W2124640962 @default.
• W2131524336 cites W2125403199 @default.
• W2131524336 cites W2126930838 @default.
• W2131524336 cites W2130862988 @default.
• W2131524336 cites W2131823335 @default.
• W2131524336 cites W2137785805 @default.
• W2131524336 cites W2147735030 @default.
• W2131524336 cites W2155185302 @default.
• W2131524336 cites W2158186000 @default.
• W2131524336 cites W2159271064 @default.
• W2131524336 cites W2160008980 @default.
• W2131524336 cites W2165052300 @default.
• W2131524336 cites W2167761850 @default.
• W2131524336 cites W2169306695 @default.
• W2131524336 cites W2171199381 @default.
• W2131524336 cites W2220387563 @default.
• W2131524336 cites W4240994224 @default.
• W2131524336 cites W4297914005 @default.
• W2131524336 cites W4368247999 @default.
• W2131524336 cites W2036426580 @default.
• W2131524336 doi "https://doi.org/10.1016/j.jagp.2013.09.003" @default.
• W2131524336 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4009389" @default.
• W2131524336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24200597" @default.
• W2131524336 hasPublicationYear "2014" @default.
• W2131524336 type Work @default.
• W2131524336 sameAs 2131524336 @default.
• W2131524336 citedByCount "19" @default.
• W2131524336 countsByYear W21315243362014 @default.
• W2131524336 countsByYear W21315243362015 @default.
• W2131524336 countsByYear W21315243362016 @default.
• W2131524336 countsByYear W21315243362017 @default.
• W2131524336 countsByYear W21315243362018 @default.
• W2131524336 countsByYear W21315243362019 @default.
• W2131524336 countsByYear W21315243362020 @default.
• W2131524336 countsByYear W21315243362021 @default.
• W2131524336 crossrefType "journal-article" @default.
• W2131524336 hasAuthorship W2131524336A5001249292 @default.
• W2131524336 hasAuthorship W2131524336A5015443550 @default.
• W2131524336 hasAuthorship W2131524336A5028614908 @default.
• W2131524336 hasAuthorship W2131524336A5035009865 @default.
• W2131524336 hasAuthorship W2131524336A5057041995 @default.
• W2131524336 hasBestOaLocation W21315243362 @default.
• W2131524336 hasConcept C118552586 @default.
• W2131524336 hasConcept C126322002 @default.
• W2131524336 hasConcept C139719470 @default.
• W2131524336 hasConcept C142724271 @default.
• W2131524336 hasConcept C156957248 @default.
• W2131524336 hasConcept C162324750 @default.
• W2131524336 hasConcept C168563851 @default.
• W2131524336 hasConcept C1862650 @default.
• W2131524336 hasConcept C204787440 @default.
• W2131524336 hasConcept C27081682 @default.
• W2131524336 hasConcept C2776867660 @default.
• W2131524336 hasConcept C2780051608 @default.
• W2131524336 hasConcept C2780733359 @default.
• W2131524336 hasConcept C2992459003 @default.
• W2131524336 hasConcept C535046627 @default.
• W2131524336 hasConcept C71924100 @default.
• W2131524336 hasConcept C95190672 @default.
• W2131524336 hasConceptScore W2131524336C118552586 @default.
• W2131524336 hasConceptScore W2131524336C126322002 @default.
• W2131524336 hasConceptScore W2131524336C139719470 @default.
• W2131524336 hasConceptScore W2131524336C142724271 @default.
• W2131524336 hasConceptScore W2131524336C156957248 @default.
• W2131524336 hasConceptScore W2131524336C162324750 @default.

• next