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- W2131621814 abstract "Industries that place metal and alloy products on the market are required to demonstrate that they are safe for all intended uses, and that any risks to humans, animals or the environment are adequately controlled. This requires reliable and robust in vitro test procedures. The aim of this study is to compare the release of alloy constituents from stainless steel powders of different grades (focus on AISI 316L) and production routes into synthetic body fluids with the release of the same metals from massive sheets in relation to material and surface characteristics. The comparison is justified by the fact that the difference between massive surfaces and powders from a metal release/dissolution and surface perspective is not clearly elucidated within current legislations. Powders and abraded and aged (24 h) massive sheets were exposed to synthetic solutions of relevance for biological settings and human exposure routes, for periods of up to one week. Concentrations of released iron, chromium, nickel, and manganese in solution were measured, and the effect of solution pH, acidity, complexation capacity, and proteins elucidated in relation to surface oxide composition and its properties. Implications for risk assessments based on in vitro metal release data from alloys are elucidated." @default.
- W2131621814 created "2016-06-24" @default.
- W2131621814 creator A5021448507 @default.
- W2131621814 creator A5060378687 @default.
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- W2131621814 date "2013-01-01" @default.
- W2131621814 modified "2023-09-30" @default.
- W2131621814 title "Metal release from stainless steel powders and massive sheets – comparison and implication for risk assessment of alloys" @default.
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- W2131621814 doi "https://doi.org/10.1039/c2em30818e" @default.
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