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- W2131834580 abstract "OBJECTIVE To assess the diagnostic value of shear wave elastography (SWE) for prostate cancer detection. MATERIALS AND METHODS In this retrospective study, 87 patients with the suspicion of prostate cancer (prostate-specific antigen > 4 ng/mL and abnormal digital rectal examination) underwent a protocol-based systematic 12-core biopsy followed by targeted biopsy at hypoechoic areas on grey-scale ultrasound. Prior to biopsy, SWE was performed by placing two circular 5 mm-sized regions of interest (ROIs) along the estimated biopsy tract in each sector and one ROI for hypoechoic lesions. SWE parameters, S (mean stiffness) and R (mean stiffness ratio), were calculated and compared regarding different histopathologic tissues and their accuracy for diagnosing prostate cancer was analyzed. SWE parameters were correlated with Gleason score and were compared between indolent ( 43.9 kPa and 60.8%, 66.4%, and 0.653, respectively, for R > 3. Both, S and R showed a significant correlation with Gleason score (r ≥ 0.296, p ≤ 0.008) and were significantly different between indolent and aggressive prostate cancer (p ≤ 0.006). CONCLUSION Shear wave elastographic parameters are significantly different between prostate cancer and benign prostate tissue and correlate with Gleason score." @default.
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- W2131834580 date "2014-01-01" @default.
- W2131834580 modified "2023-10-14" @default.
- W2131834580 title "Shear Wave Elastography for Detection of Prostate Cancer: A Preliminary Study" @default.
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- W2131834580 doi "https://doi.org/10.3348/kjr.2014.15.3.346" @default.
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