Matches in SemOpenAlex for { <https://semopenalex.org/work/W2131935976> ?p ?o ?g. }
- W2131935976 endingPage "30" @default.
- W2131935976 startingPage "24" @default.
- W2131935976 abstract "Mortality of neonates continues to be a major problem in humans and animals. IgA provides protection against microbial antigens at mucosal surfaces. Although β-carotene supplementation has been expected to enhance retinoic acid-mediated immune response in neonates, the exact mechanism by which β-carotene enhances IgA production is still unclear. We investigated the effect of supplemental β-carotene for maternal mice during pregnancy and lactation on IgA antibody-secreting cells (ASC) in mammary gland and guts and on IgA transfer from milk to neonatal mice. Pregnant mice were fed untreated or 50 mg/kg β-carotene-supplemented diets from 6·5 d postcoitus (dpc) to 14 d postpartum (dpp). Supplemental β-carotene increased the numbers of IgA ASC in mammary gland ( P < 0·05) and ileum ( P < 0·001), and also mRNA expression of IgA C-region in ileum ( P < 0·05) of maternal mice at 14 dpp, but few IgA ASC were detected in mammary gland at 17·5 dpc. IgA concentration in stomach contents, which represents milk IgA level, was significantly higher ( P < 0·01) in neonatal mice born to β-carotene-supplemented mothers at 7 and 14 dpp, and IgA concentration in serum, stomach contents and faeces increased ( P < 0·001) drastically with age. These results suggest that β-carotene supplementation for maternal mice during pregnancy and lactation is useful for enhancing IgA transfer from maternal milk to neonates owing to the increase in IgA ASC in mammary gland and ileum during lactation." @default.
- W2131935976 created "2016-06-24" @default.
- W2131935976 creator A5027464368 @default.
- W2131935976 creator A5030451172 @default.
- W2131935976 creator A5037270656 @default.
- W2131935976 creator A5053208511 @default.
- W2131935976 date "2010-08-23" @default.
- W2131935976 modified "2023-09-25" @default.
- W2131935976 title "Supplemental β-carotene increases IgA-secreting cells in mammary gland and IgA transfer from milk to neonatal mice" @default.
- W2131935976 cites W1545033764 @default.
- W2131935976 cites W1562787197 @default.
- W2131935976 cites W1598777337 @default.
- W2131935976 cites W1832228264 @default.
- W2131935976 cites W1928884554 @default.
- W2131935976 cites W1968204249 @default.
- W2131935976 cites W1975308879 @default.
- W2131935976 cites W1990823438 @default.
- W2131935976 cites W1996292767 @default.
- W2131935976 cites W2004741931 @default.
- W2131935976 cites W2013408095 @default.
- W2131935976 cites W2031551895 @default.
- W2131935976 cites W2050417626 @default.
- W2131935976 cites W2053516505 @default.
- W2131935976 cites W2060401427 @default.
- W2131935976 cites W2084123622 @default.
- W2131935976 cites W2086226733 @default.
- W2131935976 cites W2086834253 @default.
- W2131935976 cites W2093135340 @default.
- W2131935976 cites W2113540628 @default.
- W2131935976 cites W2114532842 @default.
- W2131935976 cites W2118336261 @default.
- W2131935976 cites W2121051491 @default.
- W2131935976 cites W2139162545 @default.
- W2131935976 cites W2159644025 @default.
- W2131935976 cites W2160722749 @default.
- W2131935976 cites W2164690176 @default.
- W2131935976 cites W3159289803 @default.
- W2131935976 doi "https://doi.org/10.1017/s0007114510003089" @default.
- W2131935976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20727240" @default.
- W2131935976 hasPublicationYear "2010" @default.
- W2131935976 type Work @default.
- W2131935976 sameAs 2131935976 @default.
- W2131935976 citedByCount "25" @default.
- W2131935976 countsByYear W21319359762012 @default.
- W2131935976 countsByYear W21319359762013 @default.
- W2131935976 countsByYear W21319359762014 @default.
- W2131935976 countsByYear W21319359762015 @default.
- W2131935976 countsByYear W21319359762016 @default.
- W2131935976 countsByYear W21319359762017 @default.
- W2131935976 countsByYear W21319359762018 @default.
- W2131935976 countsByYear W21319359762019 @default.
- W2131935976 countsByYear W21319359762021 @default.
- W2131935976 countsByYear W21319359762022 @default.
- W2131935976 countsByYear W21319359762023 @default.
- W2131935976 crossrefType "journal-article" @default.
- W2131935976 hasAuthorship W2131935976A5027464368 @default.
- W2131935976 hasAuthorship W2131935976A5030451172 @default.
- W2131935976 hasAuthorship W2131935976A5037270656 @default.
- W2131935976 hasAuthorship W2131935976A5053208511 @default.
- W2131935976 hasBestOaLocation W21319359761 @default.
- W2131935976 hasConcept C121608353 @default.
- W2131935976 hasConcept C126322002 @default.
- W2131935976 hasConcept C134018914 @default.
- W2131935976 hasConcept C159654299 @default.
- W2131935976 hasConcept C203014093 @default.
- W2131935976 hasConcept C2776659692 @default.
- W2131935976 hasConcept C2776940978 @default.
- W2131935976 hasConcept C2777226302 @default.
- W2131935976 hasConcept C2778001805 @default.
- W2131935976 hasConcept C2778668663 @default.
- W2131935976 hasConcept C2779073587 @default.
- W2131935976 hasConcept C2779102806 @default.
- W2131935976 hasConcept C2779234561 @default.
- W2131935976 hasConcept C2779422922 @default.
- W2131935976 hasConcept C2780898057 @default.
- W2131935976 hasConcept C530470458 @default.
- W2131935976 hasConcept C54355233 @default.
- W2131935976 hasConcept C71924100 @default.
- W2131935976 hasConcept C86803240 @default.
- W2131935976 hasConcept C8891405 @default.
- W2131935976 hasConceptScore W2131935976C121608353 @default.
- W2131935976 hasConceptScore W2131935976C126322002 @default.
- W2131935976 hasConceptScore W2131935976C134018914 @default.
- W2131935976 hasConceptScore W2131935976C159654299 @default.
- W2131935976 hasConceptScore W2131935976C203014093 @default.
- W2131935976 hasConceptScore W2131935976C2776659692 @default.
- W2131935976 hasConceptScore W2131935976C2776940978 @default.
- W2131935976 hasConceptScore W2131935976C2777226302 @default.
- W2131935976 hasConceptScore W2131935976C2778001805 @default.
- W2131935976 hasConceptScore W2131935976C2778668663 @default.
- W2131935976 hasConceptScore W2131935976C2779073587 @default.
- W2131935976 hasConceptScore W2131935976C2779102806 @default.
- W2131935976 hasConceptScore W2131935976C2779234561 @default.
- W2131935976 hasConceptScore W2131935976C2779422922 @default.
- W2131935976 hasConceptScore W2131935976C2780898057 @default.
- W2131935976 hasConceptScore W2131935976C530470458 @default.
- W2131935976 hasConceptScore W2131935976C54355233 @default.
- W2131935976 hasConceptScore W2131935976C71924100 @default.