FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2132020713> ?p ?o ?g. }

• W2132020713 endingPage "640" @default.
• W2132020713 startingPage "623" @default.
• W2132020713 abstract "1. Spontaneous Ca2+ release from the inositol 1,4,5-trisphosphate (InsP3)-sensitive stores in permeabilized hepatocytes was monitored using Fluo-3 to measure the free [Ca2+] of the medium bathing the cells. 2. Permeabilized cells rapidly sequestered Ca2+, reducing the [Ca2+] to 103 +/- 5 nM. Under conditions that depended critically upon cell density and the amount of Ca2+ in the medium, this was followed by a slow increase in [Ca2+] culminating in a substantial Ca2+ spike representing synchronous discharge from the InsP3-sensitive stores. 3. During the latency preceding the Ca2+ spike, the stores increased their sensitivity to InsP3. This sensitization seemed to be an all-or-none phenomenon. 4. Oxidized glutathione and thimerosal promoted the spontaneous release by sensitizing the InsP3 receptor. 5. An increase in the [Ca2+] within the stores was required for both the increased sensitivity to InsP3 and the subsequent spike. 6. Caffeine (6 mM) antagonized the effect of very low InsP3 concentrations and abolished the Ca2+ spike, without itself releasing Ca2+. 7. Our results suggesting that luminal Ca2+ may sensitive InsP3-sensitive stores leading to spontaneous Ca2+ mobilization will be discussed in the light of a modified version of the two-pool model for explaining cytosolic Ca2+ oscillations." @default.
• W2132020713 created "2016-06-24" @default.
• W2132020713 creator A5029742854 @default.
• W2132020713 creator A5040503192 @default.
• W2132020713 creator A5060156275 @default.
• W2132020713 date "1992-09-01" @default.
• W2132020713 modified "2023-09-23" @default.
• W2132020713 title "Luminal Ca2+ promoting spontaneous Ca2+ release from inositol trisphosphate-sensitive stores in rat hepatocytes." @default.
• W2132020713 cites W12635643 @default.
• W2132020713 cites W135766646 @default.
• W2132020713 cites W1436501061 @default.
• W2132020713 cites W1483404289 @default.
• W2132020713 cites W1492343139 @default.
• W2132020713 cites W1516800253 @default.
• W2132020713 cites W1517020408 @default.
• W2132020713 cites W1518984641 @default.
• W2132020713 cites W1532750448 @default.
• W2132020713 cites W1564829038 @default.
• W2132020713 cites W1566200309 @default.
• W2132020713 cites W1582797688 @default.
• W2132020713 cites W1586746737 @default.
• W2132020713 cites W1646639774 @default.
• W2132020713 cites W1673140014 @default.
• W2132020713 cites W1863795141 @default.
• W2132020713 cites W1979611590 @default.
• W2132020713 cites W1981229698 @default.
• W2132020713 cites W1982077267 @default.
• W2132020713 cites W1997093700 @default.
• W2132020713 cites W1997778815 @default.
• W2132020713 cites W2002744696 @default.
• W2132020713 cites W2017857318 @default.
• W2132020713 cites W2020278420 @default.
• W2132020713 cites W2021722545 @default.
• W2132020713 cites W2021847777 @default.
• W2132020713 cites W2028469352 @default.
• W2132020713 cites W2030092648 @default.
• W2132020713 cites W2033585690 @default.
• W2132020713 cites W2039351707 @default.
• W2132020713 cites W2043545589 @default.
• W2132020713 cites W2043617261 @default.
• W2132020713 cites W2045692472 @default.
• W2132020713 cites W2052739933 @default.
• W2132020713 cites W2059083135 @default.
• W2132020713 cites W2061645562 @default.
• W2132020713 cites W2062456307 @default.
• W2132020713 cites W2067254948 @default.
• W2132020713 cites W2070228801 @default.
• W2132020713 cites W2070832223 @default.
• W2132020713 cites W2070899217 @default.
• W2132020713 cites W2073263421 @default.
• W2132020713 cites W2086669662 @default.
• W2132020713 cites W2091368852 @default.
• W2132020713 cites W2091619553 @default.
• W2132020713 cites W2093198515 @default.
• W2132020713 cites W2155495069 @default.
• W2132020713 cites W2199469609 @default.
• W2132020713 cites W2395509982 @default.
• W2132020713 cites W2413549617 @default.
• W2132020713 cites W264835993 @default.
• W2132020713 doi "https://doi.org/10.1113/jphysiol.1992.sp019319" @default.
• W2132020713 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1175662" @default.
• W2132020713 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1484365" @default.
• W2132020713 hasPublicationYear "1992" @default.
• W2132020713 type Work @default.
• W2132020713 sameAs 2132020713 @default.
• W2132020713 citedByCount "132" @default.
• W2132020713 countsByYear W21320207132012 @default.
• W2132020713 countsByYear W21320207132013 @default.
• W2132020713 countsByYear W21320207132014 @default.
• W2132020713 countsByYear W21320207132015 @default.
• W2132020713 countsByYear W21320207132016 @default.
• W2132020713 countsByYear W21320207132017 @default.
• W2132020713 countsByYear W21320207132019 @default.
• W2132020713 countsByYear W21320207132020 @default.
• W2132020713 countsByYear W21320207132022 @default.
• W2132020713 countsByYear W21320207132023 @default.
• W2132020713 crossrefType "journal-article" @default.
• W2132020713 hasAuthorship W2132020713A5029742854 @default.
• W2132020713 hasAuthorship W2132020713A5040503192 @default.
• W2132020713 hasAuthorship W2132020713A5060156275 @default.
• W2132020713 hasBestOaLocation W21320207132 @default.
• W2132020713 hasConcept C12554922 @default.
• W2132020713 hasConcept C126322002 @default.
• W2132020713 hasConcept C134018914 @default.
• W2132020713 hasConcept C170493617 @default.
• W2132020713 hasConcept C178790620 @default.
• W2132020713 hasConcept C181199279 @default.
• W2132020713 hasConcept C185592680 @default.
• W2132020713 hasConcept C2777427919 @default.
• W2132020713 hasConcept C2778470358 @default.
• W2132020713 hasConcept C2778500429 @default.
• W2132020713 hasConcept C2778618036 @default.
• W2132020713 hasConcept C2781387506 @default.
• W2132020713 hasConcept C519063684 @default.
• W2132020713 hasConcept C55493867 @default.
• W2132020713 hasConcept C71924100 @default.
• W2132020713 hasConcept C86803240 @default.
• W2132020713 hasConcept C98539663 @default.

• next