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- W2132022982 abstract "Scleredema of Buschke or scleredema diabetorum is a skin complication of diabetes with deposits of collagen and aminoglycans in the dermis. This disease characterized by thickening and hardening of the skin, is usually localized in nape, back and shoulder areas. Consequences could be a decrease in motility of the shoulders and an impairment of respiratory function. Other possible complications are sleep apnoea syndrome and monoclonal gammapathy. Type 1 or type 2 diabetes may be associated with scleredema of Buschke in more than 50% of cases. Diabetes-related risk factors are long duration of the disease, presence of microangiopathy, overweight and need of insulin. Various specific treatments proposed in the literature are poorly validated. In most severe cases, radiation therapy may be useful. Sclerœdème de Buschke : une complication dermatologique méconnue du diabète Le scléroedème de Buschke ou scleredema diabetorum est une complication cutanée du diabète caractérisée par des dépôts de collagène et d'aminoglycanes dans le derme. Cette maladie marquée par un épaississement et une dureté de la peau, est localisée principalement au niveau de la nuque, du dos et des épaules. Elle peut limiter la mobilité articulaire ou la fonction respiratoire. Elle peut aussi se compliquer de syndrome d'apnées du sommeil et de gammapathie monoclonale. Les diabètes, type 1 comme type 2, sont à l'origine de plus de la moitié des cas de scléroedème de Buschke. Les facteurs de risque liés au diabète sont une longue durée d'évolution, la présence de complications de microangiopathie, une obésité et un recours à l'insulinothérapie. Les divers traitements spécifiques proposés manquent de validation. Les cas les plus graves peuvent nécessiter une radiothérapie." @default.
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- W2132022982 date "2006-11-01" @default.
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- W2132022982 title "Scleredema adultorum of Buschke: an under recognized skin complication of diabetes" @default.
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- W2132022982 doi "https://doi.org/10.1016/s1262-3636(07)70307-5" @default.
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