Matches in SemOpenAlex for { <https://semopenalex.org/work/W2132139208> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2132139208 endingPage "1317" @default.
- W2132139208 startingPage "1311" @default.
- W2132139208 abstract "Islet allotransplantation can provide insulin independence in selected individuals with type 1 diabetes. The long-term effects of these transplants on the liver are unknown. Recently, two cases of periportal steatosis after islet transplantation have been described. In this study, we performed ultrasound and magnetic resonance imaging (MRI) in 30 C-peptide-positive islet transplant recipients to detect steatosis and to explore the association of the radiological findings with clinical and metabolic factors. Steatosis was observed on MRI in six (20%) subjects. Histological findings of hepatic steatosis concurred with the imaging findings. Steatosis completely resolved in one subject whose graft failed. More subjects with steatosis required supplementary exogenous insulin than not (67 vs. 21%; P < 0.05). The clinical features of subjects with and without steatosis were otherwise similar, although C-peptide levels were higher in insulin-independent subjects with steatosis (0.98 +/- 0.12 vs. 0.70 +/- 0.18 nmol/l; P = 0.05), despite similar blood glucose levels. Serum triglycerides and the use of exogenous insulin were associated with increased odds of steatosis in a logistic regression model (chi(2) [degrees freedom] = 13.6 [2]); P = 0.001). MRI-detected steatosis is a common finding; the steatosis appears to be due to a paracrine action of insulin secreted from intrahepatic islets. Hepatic steatosis may be associated with insulin resistance or graft dysfunction." @default.
- W2132139208 created "2016-06-24" @default.
- W2132139208 creator A5006814308 @default.
- W2132139208 creator A5010478456 @default.
- W2132139208 creator A5017332392 @default.
- W2132139208 creator A5032815945 @default.
- W2132139208 creator A5066178885 @default.
- W2132139208 creator A5086545694 @default.
- W2132139208 creator A5088362754 @default.
- W2132139208 date "2004-05-01" @default.
- W2132139208 modified "2023-09-29" @default.
- W2132139208 title "Prevalence of Hepatic Steatosis After Islet Transplantation and Its Relation to Graft Function" @default.
- W2132139208 cites W1969061464 @default.
- W2132139208 cites W1974226628 @default.
- W2132139208 cites W1984053870 @default.
- W2132139208 cites W2013217093 @default.
- W2132139208 cites W2116235219 @default.
- W2132139208 cites W2117973345 @default.
- W2132139208 cites W2143299719 @default.
- W2132139208 cites W2151073893 @default.
- W2132139208 cites W2158844203 @default.
- W2132139208 cites W2160234571 @default.
- W2132139208 cites W2162051951 @default.
- W2132139208 cites W2328786770 @default.
- W2132139208 cites W2525830412 @default.
- W2132139208 cites W2615637571 @default.
- W2132139208 doi "https://doi.org/10.2337/diabetes.53.5.1311" @default.
- W2132139208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15111501" @default.
- W2132139208 hasPublicationYear "2004" @default.
- W2132139208 type Work @default.
- W2132139208 sameAs 2132139208 @default.
- W2132139208 citedByCount "150" @default.
- W2132139208 countsByYear W21321392082012 @default.
- W2132139208 countsByYear W21321392082013 @default.
- W2132139208 countsByYear W21321392082014 @default.
- W2132139208 countsByYear W21321392082015 @default.
- W2132139208 countsByYear W21321392082016 @default.
- W2132139208 countsByYear W21321392082017 @default.
- W2132139208 countsByYear W21321392082018 @default.
- W2132139208 countsByYear W21321392082019 @default.
- W2132139208 countsByYear W21321392082020 @default.
- W2132139208 countsByYear W21321392082021 @default.
- W2132139208 countsByYear W21321392082022 @default.
- W2132139208 countsByYear W21321392082023 @default.
- W2132139208 crossrefType "journal-article" @default.
- W2132139208 hasAuthorship W2132139208A5006814308 @default.
- W2132139208 hasAuthorship W2132139208A5010478456 @default.
- W2132139208 hasAuthorship W2132139208A5017332392 @default.
- W2132139208 hasAuthorship W2132139208A5032815945 @default.
- W2132139208 hasAuthorship W2132139208A5066178885 @default.
- W2132139208 hasAuthorship W2132139208A5086545694 @default.
- W2132139208 hasAuthorship W2132139208A5088362754 @default.
- W2132139208 hasBestOaLocation W21321392081 @default.
- W2132139208 hasConcept C126322002 @default.
- W2132139208 hasConcept C134018914 @default.
- W2132139208 hasConcept C165220095 @default.
- W2132139208 hasConcept C2776175330 @default.
- W2132139208 hasConcept C2777391703 @default.
- W2132139208 hasConcept C2779306644 @default.
- W2132139208 hasConcept C2779609443 @default.
- W2132139208 hasConcept C2911091166 @default.
- W2132139208 hasConcept C555293320 @default.
- W2132139208 hasConcept C71924100 @default.
- W2132139208 hasConcept C90924648 @default.
- W2132139208 hasConceptScore W2132139208C126322002 @default.
- W2132139208 hasConceptScore W2132139208C134018914 @default.
- W2132139208 hasConceptScore W2132139208C165220095 @default.
- W2132139208 hasConceptScore W2132139208C2776175330 @default.
- W2132139208 hasConceptScore W2132139208C2777391703 @default.
- W2132139208 hasConceptScore W2132139208C2779306644 @default.
- W2132139208 hasConceptScore W2132139208C2779609443 @default.
- W2132139208 hasConceptScore W2132139208C2911091166 @default.
- W2132139208 hasConceptScore W2132139208C555293320 @default.
- W2132139208 hasConceptScore W2132139208C71924100 @default.
- W2132139208 hasConceptScore W2132139208C90924648 @default.
- W2132139208 hasIssue "5" @default.
- W2132139208 hasLocation W21321392081 @default.
- W2132139208 hasLocation W21321392082 @default.
- W2132139208 hasOpenAccess W2132139208 @default.
- W2132139208 hasPrimaryLocation W21321392081 @default.
- W2132139208 hasRelatedWork W138803513 @default.
- W2132139208 hasRelatedWork W1973049774 @default.
- W2132139208 hasRelatedWork W1986132654 @default.
- W2132139208 hasRelatedWork W2010140898 @default.
- W2132139208 hasRelatedWork W2031301348 @default.
- W2132139208 hasRelatedWork W2044823377 @default.
- W2132139208 hasRelatedWork W2064538767 @default.
- W2132139208 hasRelatedWork W2069827981 @default.
- W2132139208 hasRelatedWork W2082140668 @default.
- W2132139208 hasRelatedWork W4234612679 @default.
- W2132139208 hasVolume "53" @default.
- W2132139208 isParatext "false" @default.
- W2132139208 isRetracted "false" @default.
- W2132139208 magId "2132139208" @default.
- W2132139208 workType "article" @default.