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- W2132157045 abstract "Recent years have seen the way in which the analytical electron microscope has been applied to problems involving thin specimens in metallurgy, mineralogy and many branches of biology. The limits of sensitivity have been explored and its potential usefulness in these fields investigated. Problems concerning the interaction of electrons with the specimen are discussed in relation to the correct choice of operating conditions and specimen preparation. In biological work, frozen sections provide new information about subcellular elemental localization of mobile electrolytes, while analysis of tissue prepared by conventional means is used to detect physiological levels of some naturally occurring elements. Examination of mineral dispersions provides analysis of particles just 10 nm thick, visible only in transmission electron microscopy, and further work with thin metal foils confirms the value of high resolution transmission imaging as a complementary facility to micro-analysis. Work has been done to investigate the possibilities of improving sensitivities both by changing operational parameters and instrumental design, and the value of quantitation in thin specimen analysis explored." @default.
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- W2132157045 date "1973-08-01" @default.
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- W2132157045 title "Recent developments in analytical electron microscopy" @default.
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- W2132157045 doi "https://doi.org/10.1111/j.1365-2818.1973.tb03840.x" @default.
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