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• W2132196633 endingPage "930" @default.
• W2132196633 startingPage "922" @default.
• W2132196633 abstract "Refractory status epilepticus (RSE) is defined as status epilepticus that continues despite treatment with benzodiazepines and one antiepileptic drug. RSE should be treated promptly to prevent morbidity and mortality; however, scarce evidence is available to support the choice of specific treatments. Major independent outcome predictors are age (not modifiable) and cause (which should be actively targeted). Recent recommendations for adults suggest that the aggressiveness of treatment for RSE should be tailored to the clinical situation. To minimise intensive care unit-related complications, focal RSE without impairment of consciousness might initially be approached conservatively; conversely, early induction of pharmacological coma is advisable in generalised convulsive forms of the disorder. At this stage, midazolam, propofol, or barbiturates are the most commonly used drugs. Several other treatments, such as additional anaesthetics, other antiepileptic or immunomodulatory compounds, or non-pharmacological approaches (eg, electroconvulsive treatment or hypothermia), have been used in protracted RSE. Treatment lasting weeks or months can sometimes result in a good outcome, as in selected patients after encephalitis or autoimmune disorders. Well designed prospective studies of RSE are urgently needed. Refractory status epilepticus (RSE) is defined as status epilepticus that continues despite treatment with benzodiazepines and one antiepileptic drug. RSE should be treated promptly to prevent morbidity and mortality; however, scarce evidence is available to support the choice of specific treatments. Major independent outcome predictors are age (not modifiable) and cause (which should be actively targeted). Recent recommendations for adults suggest that the aggressiveness of treatment for RSE should be tailored to the clinical situation. To minimise intensive care unit-related complications, focal RSE without impairment of consciousness might initially be approached conservatively; conversely, early induction of pharmacological coma is advisable in generalised convulsive forms of the disorder. At this stage, midazolam, propofol, or barbiturates are the most commonly used drugs. Several other treatments, such as additional anaesthetics, other antiepileptic or immunomodulatory compounds, or non-pharmacological approaches (eg, electroconvulsive treatment or hypothermia), have been used in protracted RSE. Treatment lasting weeks or months can sometimes result in a good outcome, as in selected patients after encephalitis or autoimmune disorders. Well designed prospective studies of RSE are urgently needed." @default.
• W2132196633 created "2016-06-24" @default.
• W2132196633 creator A5003722970 @default.
• W2132196633 creator A5045206939 @default.
• W2132196633 date "2011-10-01" @default.
• W2132196633 modified "2023-10-12" @default.
• W2132196633 title "Management of refractory status epilepticus in adults: still more questions than answers" @default.
• W2132196633 cites W1492512073 @default.
• W2132196633 cites W1510058344 @default.
• W2132196633 cites W1537500202 @default.
• W2132196633 cites W1573800003 @default.
• W2132196633 cites W1746578757 @default.
• W2132196633 cites W1793366199 @default.
• W2132196633 cites W1803953876 @default.
• W2132196633 cites W1925921463 @default.
• W2132196633 cites W1963604986 @default.
• W2132196633 cites W1966201948 @default.
• W2132196633 cites W1966655960 @default.
• W2132196633 cites W1969777964 @default.
• W2132196633 cites W1972441224 @default.
• W2132196633 cites W1972462634 @default.
• W2132196633 cites W1973522012 @default.
• W2132196633 cites W1974405376 @default.
• W2132196633 cites W1978006718 @default.
• W2132196633 cites W1980669612 @default.
• W2132196633 cites W1980734822 @default.
• W2132196633 cites W1988358928 @default.
• W2132196633 cites W1988502678 @default.
• W2132196633 cites W1989722965 @default.
• W2132196633 cites W1989851136 @default.
• W2132196633 cites W1991690674 @default.
• W2132196633 cites W1991949384 @default.
• W2132196633 cites W1992916966 @default.
• W2132196633 cites W1994421931 @default.
• W2132196633 cites W1994889588 @default.
• W2132196633 cites W1995683461 @default.
• W2132196633 cites W1996942889 @default.
• W2132196633 cites W1997129135 @default.
• W2132196633 cites W2000137656 @default.
• W2132196633 cites W2000204672 @default.
• W2132196633 cites W2003694944 @default.
• W2132196633 cites W2004158952 @default.
• W2132196633 cites W2008452090 @default.
• W2132196633 cites W2010354407 @default.
• W2132196633 cites W2012318617 @default.
• W2132196633 cites W2013705874 @default.
• W2132196633 cites W2015311425 @default.
• W2132196633 cites W2016128904 @default.
• W2132196633 cites W2016486532 @default.
• W2132196633 cites W2018537604 @default.
• W2132196633 cites W2021360813 @default.
• W2132196633 cites W2022264741 @default.
• W2132196633 cites W2024150197 @default.
• W2132196633 cites W2025742662 @default.
• W2132196633 cites W2027177883 @default.
• W2132196633 cites W2027311472 @default.
• W2132196633 cites W2028772150 @default.
• W2132196633 cites W2030819816 @default.
• W2132196633 cites W2031003242 @default.
• W2132196633 cites W2032485643 @default.
• W2132196633 cites W2036114285 @default.
• W2132196633 cites W2036467957 @default.
• W2132196633 cites W2037199501 @default.
• W2132196633 cites W2039216284 @default.
• W2132196633 cites W2041097270 @default.
• W2132196633 cites W2045409885 @default.
• W2132196633 cites W2045546798 @default.
• W2132196633 cites W2045765644 @default.
• W2132196633 cites W2046457967 @default.
• W2132196633 cites W2049175903 @default.
• W2132196633 cites W2050499388 @default.
• W2132196633 cites W2052357631 @default.
• W2132196633 cites W2054080711 @default.
• W2132196633 cites W2056821940 @default.
• W2132196633 cites W2057157397 @default.
• W2132196633 cites W2058772453 @default.
• W2132196633 cites W2059208446 @default.
• W2132196633 cites W2062216654 @default.
• W2132196633 cites W2063689497 @default.
• W2132196633 cites W2064267630 @default.
• W2132196633 cites W2065576824 @default.
• W2132196633 cites W2067749389 @default.
• W2132196633 cites W2069507189 @default.
• W2132196633 cites W2070693750 @default.
• W2132196633 cites W2070850426 @default.
• W2132196633 cites W2071542329 @default.
• W2132196633 cites W2071725069 @default.
• W2132196633 cites W2074426135 @default.
• W2132196633 cites W2075057287 @default.
• W2132196633 cites W2076463360 @default.
• W2132196633 cites W2077798248 @default.
• W2132196633 cites W2080094155 @default.
• W2132196633 cites W2080157290 @default.
• W2132196633 cites W2080631264 @default.
• W2132196633 cites W2083310100 @default.
• W2132196633 cites W2084677933 @default.
• W2132196633 cites W2085682222 @default.
• W2132196633 cites W2086102215 @default.

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