FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2132255268> ?p ?o ?g. }

• W2132255268 endingPage "385.e13" @default.
• W2132255268 startingPage "385.e7" @default.
• W2132255268 abstract "Genetic variations among patients with prostate cancer (PCa) who underwent radical prostatectomies were evaluated to predict advanced stage above T3 using an exome single nucleotide polymorphism (SNP) chip array.We collected data of genetic SNP variants from 820 patients with PCa who underwent radical prostatectomy (RP) using a custom HumanExome BeadChip v1.0 (Illumina Inc.). We selected the SNPs that were most significantly associated with advanced-stage PCa (≥ T3) among the 242,186 SNPs that were genotyped, and we compared the accuracies of the associations using a multivariate logistic model that incorporated clinical factors and clinicogenetic factors.Among the total cohort, 360 patients (43.9%) had advanced pathologic stage (≥ T3) after RP, of whom 262 (32.0%) had extracapsular extensions, 79 (9.6%) had seminal vesicle invasions, and 10 (1.3%) had bladder neck invasions. The exome array analysis indicated that 5 SNPs (rs6804162, rs8055236, rs56335308, rs6104, and rs12618769) were significant for predicting T3 stage after RP in patients with PCa. These genetic markers were significant factors after adjusting for other clinical parameters, and they increased the accuracy of a multivariate model for predicting advanced stage of PCa (83.9%-87.2%, P = 0.0001).Based on a genetic array, the selected SNPs were found to be independent predictors for advanced stage after RP, and the addition of individualized genetic information effectively enhanced the accuracy of predicting advanced-stage disease. These results should be validated in another independent cohort." @default.
• W2132255268 created "2016-06-24" @default.
• W2132255268 creator A5018564062 @default.
• W2132255268 creator A5019050469 @default.
• W2132255268 creator A5032958224 @default.
• W2132255268 creator A5035133412 @default.
• W2132255268 creator A5048067707 @default.
• W2132255268 creator A5048067770 @default.
• W2132255268 creator A5052439030 @default.
• W2132255268 creator A5052489990 @default.
• W2132255268 creator A5063111787 @default.
• W2132255268 creator A5086877012 @default.
• W2132255268 date "2015-09-01" @default.
• W2132255268 modified "2023-10-14" @default.
• W2132255268 title "Genome-wide detection of allelic genetic variation to predict advanced-stage prostate cancer after radical prostatectomy using an exome SNP chip" @default.
• W2132255268 cites W1538845011 @default.
• W2132255268 cites W1761725668 @default.
• W2132255268 cites W1826574233 @default.
• W2132255268 cites W1968420713 @default.
• W2132255268 cites W1977546001 @default.
• W2132255268 cites W1981580846 @default.
• W2132255268 cites W1985165055 @default.
• W2132255268 cites W1986345593 @default.
• W2132255268 cites W2000385281 @default.
• W2132255268 cites W2001526794 @default.
• W2132255268 cites W2004429375 @default.
• W2132255268 cites W2008640176 @default.
• W2132255268 cites W2019701250 @default.
• W2132255268 cites W2026254493 @default.
• W2132255268 cites W2030705868 @default.
• W2132255268 cites W2058334562 @default.
• W2132255268 cites W2069298570 @default.
• W2132255268 cites W2082202613 @default.
• W2132255268 cites W2086152285 @default.
• W2132255268 cites W2110297592 @default.
• W2132255268 cites W2123377260 @default.
• W2132255268 cites W2128165053 @default.
• W2132255268 cites W2142658264 @default.
• W2132255268 cites W2153328120 @default.
• W2132255268 cites W2161817637 @default.
• W2132255268 cites W2268606640 @default.
• W2132255268 cites W2300440828 @default.
• W2132255268 cites W2405877977 @default.
• W2132255268 cites W2423694980 @default.
• W2132255268 cites W2069494446 @default.
• W2132255268 doi "https://doi.org/10.1016/j.urolonc.2015.05.016" @default.
• W2132255268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26087972" @default.
• W2132255268 hasPublicationYear "2015" @default.
• W2132255268 type Work @default.
• W2132255268 sameAs 2132255268 @default.
• W2132255268 citedByCount "0" @default.
• W2132255268 crossrefType "journal-article" @default.
• W2132255268 hasAuthorship W2132255268A5018564062 @default.
• W2132255268 hasAuthorship W2132255268A5019050469 @default.
• W2132255268 hasAuthorship W2132255268A5032958224 @default.
• W2132255268 hasAuthorship W2132255268A5035133412 @default.
• W2132255268 hasAuthorship W2132255268A5048067707 @default.
• W2132255268 hasAuthorship W2132255268A5048067770 @default.
• W2132255268 hasAuthorship W2132255268A5052439030 @default.
• W2132255268 hasAuthorship W2132255268A5052489990 @default.
• W2132255268 hasAuthorship W2132255268A5063111787 @default.
• W2132255268 hasAuthorship W2132255268A5086877012 @default.
• W2132255268 hasConcept C104317684 @default.
• W2132255268 hasConcept C10590036 @default.
• W2132255268 hasConcept C121608353 @default.
• W2132255268 hasConcept C126322002 @default.
• W2132255268 hasConcept C135763542 @default.
• W2132255268 hasConcept C139275648 @default.
• W2132255268 hasConcept C143998085 @default.
• W2132255268 hasConcept C146357865 @default.
• W2132255268 hasConcept C151730666 @default.
• W2132255268 hasConcept C153209595 @default.
• W2132255268 hasConcept C163691529 @default.
• W2132255268 hasConcept C16671776 @default.
• W2132255268 hasConcept C2779466945 @default.
• W2132255268 hasConcept C2780192828 @default.
• W2132255268 hasConcept C501734568 @default.
• W2132255268 hasConcept C54355233 @default.
• W2132255268 hasConcept C71924100 @default.
• W2132255268 hasConcept C86803240 @default.
• W2132255268 hasConceptScore W2132255268C104317684 @default.
• W2132255268 hasConceptScore W2132255268C10590036 @default.
• W2132255268 hasConceptScore W2132255268C121608353 @default.
• W2132255268 hasConceptScore W2132255268C126322002 @default.
• W2132255268 hasConceptScore W2132255268C135763542 @default.
• W2132255268 hasConceptScore W2132255268C139275648 @default.
• W2132255268 hasConceptScore W2132255268C143998085 @default.
• W2132255268 hasConceptScore W2132255268C146357865 @default.
• W2132255268 hasConceptScore W2132255268C151730666 @default.
• W2132255268 hasConceptScore W2132255268C153209595 @default.
• W2132255268 hasConceptScore W2132255268C163691529 @default.
• W2132255268 hasConceptScore W2132255268C16671776 @default.
• W2132255268 hasConceptScore W2132255268C2779466945 @default.
• W2132255268 hasConceptScore W2132255268C2780192828 @default.
• W2132255268 hasConceptScore W2132255268C501734568 @default.
• W2132255268 hasConceptScore W2132255268C54355233 @default.
• W2132255268 hasConceptScore W2132255268C71924100 @default.
• W2132255268 hasConceptScore W2132255268C86803240 @default.

• next