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- W2132270923 abstract "Background: The number of nucleated cells (NC) infused into the recipient is highly correlated with the probability and speed of cord blood (CB) hematopoietic stem cell transplantation; therefore it is necessary to obtain CB units with sufficient NCs. Study design and methods: Cord blood was collected from normal vaginal and cesarean deliveries with placenta in uterus and immediately processed and assessed for volume NC count, CD34 + cell count and CFU-GM. These parameters were then processed and analyzed to find out whether they are correlated with maternal and neonatal characteristics such as mother's age, parity, gestational age, babies birth weight, and sex. Results: CB had a higher volume in samples taken from cesarean deliveries with an open collection method in comparison with samples collected from vaginal deliveries with a closed collection method. No significant correlation was found between maternal-neonatal factors and CB parameters in vaginal deliveries; while in cesarean cases, male newborns have a higher volume and cell count. In multiparous women, CB cell counts are higher than women who have a parity of 1 or 2 (ALL p <0.05). Volume reduction with a ratio of one part hespan to five parts blood recovered more NC (88%) than a ratio of one to seven (73%). Conclusion: : It can be concluded that CB parameters were influenced by the collection method, processing technique, maternal and neonatal factors." @default.
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- W2132270923 date "2004-01-01" @default.
- W2132270923 modified "2023-09-27" @default.
- W2132270923 title "Evaluation of the Affect of Maternal and Neonatal Factors on Cord Blood Parameters" @default.
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