Matches in SemOpenAlex for { <https://semopenalex.org/work/W2132531241> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2132531241 abstract "We have analyzed the histone genes from the sea urchin Lytechinus pictus. Examination of native DNA from individuals reveals four major Eco RI restriction endonuclease histone gene DNA fragments which have been labeled A (6.0 kb), B (4.1 kb), C (3.1kb) and D (1.2 kb). The fragments A, B and C have been cloned into E. coli plasmids (pLpA, pLpB and pLpC). These histone gene fragments display length and sequence heterogeneity in different individuals. The plasmid pLpA contains the coding regions for H1, H4, H2B and H3 histones, and we determined that the DNA fragment D is tandem to A in native DNA and that it contains the H2A gene. The plasmids pLpB and pLpC contain the histone genes H2A-H1-H4 and H2B-H3, respectively, and together contain the sequences for the five major histones. Restriction analysis of native L. pictus DNA reveals that B and C are tandem to each other but not intermingled with the A--D-type repeat units, and are thus in separate clusters with a repeat length of 7.2 kb. Since the two cluster types do not segregate, they are not alleles. Hybridization of histone mRNA to exonuclease III-digested linear DNA demonstrated an identical polarity of the histone genes in the A--D- and B--C-type repeat units. This result revealed that the L. pictus histone genes have a polarity which is the same as other sea urchin histone genes examined to date--that is, 3' H1-H4-H2B-H3-H2A 5'. Restriction endonuclease cleavage patterns of the cloned segments indicate that considerable sequence heterogeneity exists between the two types of histone gene repeat units." @default.
- W2132531241 created "2016-06-24" @default.
- W2132531241 creator A5068903211 @default.
- W2132531241 creator A5071577935 @default.
- W2132531241 date "1979-11-01" @default.
- W2132531241 modified "2023-09-27" @default.
- W2132531241 title "Nonallelic histone gene clusters of individual sea urchins (Lytechinus pictus): Polarity and gene organization" @default.
- W2132531241 cites W1858120728 @default.
- W2132531241 cites W1967388793 @default.
- W2132531241 cites W1968353273 @default.
- W2132531241 cites W1968697334 @default.
- W2132531241 cites W1969804030 @default.
- W2132531241 cites W1970610957 @default.
- W2132531241 cites W1977532037 @default.
- W2132531241 cites W1986453228 @default.
- W2132531241 cites W1991518741 @default.
- W2132531241 cites W1998231415 @default.
- W2132531241 cites W2004158443 @default.
- W2132531241 cites W2006054761 @default.
- W2132531241 cites W2012096611 @default.
- W2132531241 cites W2020559947 @default.
- W2132531241 cites W2056373147 @default.
- W2132531241 cites W2063450941 @default.
- W2132531241 cites W2076207372 @default.
- W2132531241 cites W2088204427 @default.
- W2132531241 cites W2091001646 @default.
- W2132531241 cites W2095471935 @default.
- W2132531241 cites W2100959763 @default.
- W2132531241 cites W2115458736 @default.
- W2132531241 cites W2125658528 @default.
- W2132531241 cites W4211150601 @default.
- W2132531241 doi "https://doi.org/10.1016/0092-8674(79)90136-3" @default.
- W2132531241 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/519757" @default.
- W2132531241 hasPublicationYear "1979" @default.
- W2132531241 type Work @default.
- W2132531241 sameAs 2132531241 @default.
- W2132531241 citedByCount "28" @default.
- W2132531241 countsByYear W21325312412017 @default.
- W2132531241 crossrefType "journal-article" @default.
- W2132531241 hasAuthorship W2132531241A5068903211 @default.
- W2132531241 hasAuthorship W2132531241A5071577935 @default.
- W2132531241 hasConcept C101152365 @default.
- W2132531241 hasConcept C104317684 @default.
- W2132531241 hasConcept C150194340 @default.
- W2132531241 hasConcept C153911025 @default.
- W2132531241 hasConcept C190727270 @default.
- W2132531241 hasConcept C22709980 @default.
- W2132531241 hasConcept C2779085176 @default.
- W2132531241 hasConcept C54355233 @default.
- W2132531241 hasConcept C56428682 @default.
- W2132531241 hasConcept C64927066 @default.
- W2132531241 hasConcept C86803240 @default.
- W2132531241 hasConceptScore W2132531241C101152365 @default.
- W2132531241 hasConceptScore W2132531241C104317684 @default.
- W2132531241 hasConceptScore W2132531241C150194340 @default.
- W2132531241 hasConceptScore W2132531241C153911025 @default.
- W2132531241 hasConceptScore W2132531241C190727270 @default.
- W2132531241 hasConceptScore W2132531241C22709980 @default.
- W2132531241 hasConceptScore W2132531241C2779085176 @default.
- W2132531241 hasConceptScore W2132531241C54355233 @default.
- W2132531241 hasConceptScore W2132531241C56428682 @default.
- W2132531241 hasConceptScore W2132531241C64927066 @default.
- W2132531241 hasConceptScore W2132531241C86803240 @default.
- W2132531241 hasLocation W21325312411 @default.
- W2132531241 hasLocation W21325312412 @default.
- W2132531241 hasOpenAccess W2132531241 @default.
- W2132531241 hasPrimaryLocation W21325312411 @default.
- W2132531241 hasRelatedWork W1597765827 @default.
- W2132531241 hasRelatedWork W1605425036 @default.
- W2132531241 hasRelatedWork W1970886892 @default.
- W2132531241 hasRelatedWork W1986693701 @default.
- W2132531241 hasRelatedWork W1997446743 @default.
- W2132531241 hasRelatedWork W2011651739 @default.
- W2132531241 hasRelatedWork W2051217516 @default.
- W2132531241 hasRelatedWork W2069179692 @default.
- W2132531241 hasRelatedWork W2138328029 @default.
- W2132531241 hasRelatedWork W2146091491 @default.
- W2132531241 isParatext "false" @default.
- W2132531241 isRetracted "false" @default.
- W2132531241 magId "2132531241" @default.
- W2132531241 workType "article" @default.