FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2132533422> ?p ?o ?g. }

• W2132533422 endingPage "385" @default.
• W2132533422 startingPage "375" @default.
• W2132533422 abstract "The Ctf19 multi-protein complex of the central kinetochore in Saccharomyces cerevisiae is required for precise chromosome segregation during mitosis. Of 11 proteins of this complex, at least six are required for cell survival when microtubules are defective. To find individual roles of these proteins in kinetochore stability, double deletion mutants of the corresponding genes were constructed in several combinations. The growth phenotype of all the mutants was in accordance with the current model of hierarchical assembly of kinetochore proteins except one that lacked CHL4 and IML3 genes in a tubulin-defective background (tub1-1 chl4 iml3). tub1-1 chl4 iml3 showed synergistic growth defect, decrease in minichromosome stability compared with its single mutants, and a greater accumulation of cells at the G2/M checkpoint of the cell cycle. Furthermore, in the absence of Iml3p, the two-hybrid interaction between Ctf19p (a member of the Ctf19 complex) and Dam1p (a member of the outer kinetochore DASH complex) was disrupted and the localization of Dam1p at the kinetochore was also compromised. These results indicate a role for Iml3p distinct from Chl4p at the kinetochore. Iml3p may be acting as a link between the central and the outer complexes thus contributing to a functional kinetochore." @default.
• W2132533422 created "2016-06-24" @default.
• W2132533422 creator A5031952469 @default.
• W2132533422 creator A5044845990 @default.
• W2132533422 creator A5055725540 @default.
• W2132533422 date "2013-04-02" @default.
• W2132533422 modified "2023-09-24" @default.
• W2132533422 title "Iml3p, a component of the Ctf19 complex of the budding yeast kinetochore is required to maintain kinetochore integrity under conditions of spindle stress" @default.
• W2132533422 cites W1572344453 @default.
• W2132533422 cites W1895018249 @default.
• W2132533422 cites W1903792504 @default.
• W2132533422 cites W1966072209 @default.
• W2132533422 cites W1967390330 @default.
• W2132533422 cites W1967696278 @default.
• W2132533422 cites W1976725559 @default.
• W2132533422 cites W1986157458 @default.
• W2132533422 cites W1992431849 @default.
• W2132533422 cites W2004304492 @default.
• W2132533422 cites W2011540715 @default.
• W2132533422 cites W2060049752 @default.
• W2132533422 cites W2062214822 @default.
• W2132533422 cites W2073126069 @default.
• W2132533422 cites W2074537036 @default.
• W2132533422 cites W2080103099 @default.
• W2132533422 cites W2084737875 @default.
• W2132533422 cites W2085844153 @default.
• W2132533422 cites W2088156810 @default.
• W2132533422 cites W2092989086 @default.
• W2132533422 cites W2095465286 @default.
• W2132533422 cites W2108994146 @default.
• W2132533422 cites W2119848745 @default.
• W2132533422 cites W2125280178 @default.
• W2132533422 cites W2126604711 @default.
• W2132533422 cites W2126909443 @default.
• W2132533422 cites W2130141461 @default.
• W2132533422 cites W2145859809 @default.
• W2132533422 cites W2147831861 @default.
• W2132533422 cites W2151548971 @default.
• W2132533422 cites W2153890323 @default.
• W2132533422 cites W2154020701 @default.
• W2132533422 cites W2157980476 @default.
• W2132533422 cites W2165268265 @default.
• W2132533422 cites W2170499370 @default.
• W2132533422 cites W2171644600 @default.
• W2132533422 cites W2290326536 @default.
• W2132533422 doi "https://doi.org/10.1111/1567-1364.12041" @default.
• W2132533422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23480593" @default.
• W2132533422 hasPublicationYear "2013" @default.
• W2132533422 type Work @default.
• W2132533422 sameAs 2132533422 @default.
• W2132533422 citedByCount "6" @default.
• W2132533422 countsByYear W21325334222013 @default.
• W2132533422 countsByYear W21325334222014 @default.
• W2132533422 countsByYear W21325334222015 @default.
• W2132533422 countsByYear W21325334222019 @default.
• W2132533422 countsByYear W21325334222021 @default.
• W2132533422 crossrefType "journal-article" @default.
• W2132533422 hasAuthorship W2132533422A5031952469 @default.
• W2132533422 hasAuthorship W2132533422A5044845990 @default.
• W2132533422 hasAuthorship W2132533422A5055725540 @default.
• W2132533422 hasBestOaLocation W21325334221 @default.
• W2132533422 hasConcept C104317684 @default.
• W2132533422 hasConcept C1491633281 @default.
• W2132533422 hasConcept C192838845 @default.
• W2132533422 hasConcept C20418707 @default.
• W2132533422 hasConcept C2777576037 @default.
• W2132533422 hasConcept C2778354886 @default.
• W2132533422 hasConcept C2780091387 @default.
• W2132533422 hasConcept C30481170 @default.
• W2132533422 hasConcept C47432576 @default.
• W2132533422 hasConcept C54355233 @default.
• W2132533422 hasConcept C63491729 @default.
• W2132533422 hasConcept C6391034 @default.
• W2132533422 hasConcept C85813293 @default.
• W2132533422 hasConcept C86803240 @default.
• W2132533422 hasConcept C93304396 @default.
• W2132533422 hasConcept C95444343 @default.
• W2132533422 hasConceptScore W2132533422C104317684 @default.
• W2132533422 hasConceptScore W2132533422C1491633281 @default.
• W2132533422 hasConceptScore W2132533422C192838845 @default.
• W2132533422 hasConceptScore W2132533422C20418707 @default.
• W2132533422 hasConceptScore W2132533422C2777576037 @default.
• W2132533422 hasConceptScore W2132533422C2778354886 @default.
• W2132533422 hasConceptScore W2132533422C2780091387 @default.
• W2132533422 hasConceptScore W2132533422C30481170 @default.
• W2132533422 hasConceptScore W2132533422C47432576 @default.
• W2132533422 hasConceptScore W2132533422C54355233 @default.
• W2132533422 hasConceptScore W2132533422C63491729 @default.
• W2132533422 hasConceptScore W2132533422C6391034 @default.
• W2132533422 hasConceptScore W2132533422C85813293 @default.
• W2132533422 hasConceptScore W2132533422C86803240 @default.
• W2132533422 hasConceptScore W2132533422C93304396 @default.
• W2132533422 hasConceptScore W2132533422C95444343 @default.
• W2132533422 hasIssue "4" @default.
• W2132533422 hasLocation W21325334221 @default.
• W2132533422 hasLocation W21325334222 @default.
• W2132533422 hasOpenAccess W2132533422 @default.
• W2132533422 hasPrimaryLocation W21325334221 @default.

• next