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- W2132571570 abstract "Mitochondria are critical subcellular organelles that are required for several metabolic processes, including oxidative phosphorylation, as well as signaling and tissue-specific processes. Current understanding of the role of mitochondria in both the innate and adaptive immune systems is expanding. Concurrently, immunodeficiencies arising from perturbation of mitochondrial elements are increasingly recognized. Recent observations of immune dysfunction and increased incidence of infection in patients with primary mitochondrial disorders further support an important role for mitochondria in the proper function of the immune system. Here we review current findings." @default.
- W2132571570 created "2016-06-24" @default.
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- W2132571570 date "2014-01-01" @default.
- W2132571570 modified "2023-09-25" @default.
- W2132571570 title "Powering the Immune System: Mitochondria in Immune Function and Deficiency" @default.
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- W2132571570 doi "https://doi.org/10.1155/2014/164309" @default.
- W2132571570 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4189529" @default.
- W2132571570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25309931" @default.
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