Matches in SemOpenAlex for { <https://semopenalex.org/work/W2132587122> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2132587122 endingPage "1590" @default.
- W2132587122 startingPage "1586" @default.
- W2132587122 abstract "We investigated the dose-response effect of positive end-expiratory pressure (PEEP) and increased lung volume on the pulmonary clearance rate of aerosolized technetium-99m-labeled diethylenetriaminepentaacetic acid (99mTc-DTPA). Clearance of lung radioactivity was expressed as percent decrease per minute. Base-line clearance was measured while anesthetized sheep (n = 20) were ventilated with 0 cmH2O end-expiratory pressure. Clearance was remeasured during ventilation at 2.5, 5, 10, 15, or 20 cmH2O PEEP. Further studies showed stepwise increases in functional residual capacity (FRC) (P less than 0.05) measured at 0, 2.5, 5, 10, 15, and 20 cmH2O PEEP. At 2.5 cmH2O PEEP, the clearance rate was not different from that at base line (P less than 0.05), although FRC was increased from base line. Clearance rate increased progressively with increasing PEEP at 5, 10, and 15 cmH2O (P less than 0.05). Between 15 and 20 cmH2O PEEP, clearance rate was again unchanged, despite an increase in FRC. The pulmonary clearance of aerosolized 99mTc-DTPA shows a sigmoidal response to increasing FRC and PEEP, having both threshold and maximal effects. This relationship is most consistent with the hypothesis that alveolar epithelial permeability is increased by lung inflation." @default.
- W2132587122 created "2016-06-24" @default.
- W2132587122 creator A5007096151 @default.
- W2132587122 creator A5011756238 @default.
- W2132587122 creator A5068310637 @default.
- W2132587122 creator A5077465646 @default.
- W2132587122 date "1987-10-01" @default.
- W2132587122 modified "2023-09-23" @default.
- W2132587122 title "Relationship of end-expiratory pressure, lung volume, and 99mTc-DTPA clearance" @default.
- W2132587122 doi "https://doi.org/10.1152/jappl.1987.63.4.1586" @default.
- W2132587122 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3320010" @default.
- W2132587122 hasPublicationYear "1987" @default.
- W2132587122 type Work @default.
- W2132587122 sameAs 2132587122 @default.
- W2132587122 citedByCount "36" @default.
- W2132587122 countsByYear W21325871222012 @default.
- W2132587122 countsByYear W21325871222013 @default.
- W2132587122 countsByYear W21325871222014 @default.
- W2132587122 countsByYear W21325871222016 @default.
- W2132587122 crossrefType "journal-article" @default.
- W2132587122 hasAuthorship W2132587122A5007096151 @default.
- W2132587122 hasAuthorship W2132587122A5011756238 @default.
- W2132587122 hasAuthorship W2132587122A5068310637 @default.
- W2132587122 hasAuthorship W2132587122A5077465646 @default.
- W2132587122 hasConcept C126322002 @default.
- W2132587122 hasConcept C127413603 @default.
- W2132587122 hasConcept C136936797 @default.
- W2132587122 hasConcept C18206936 @default.
- W2132587122 hasConcept C200457457 @default.
- W2132587122 hasConcept C27101514 @default.
- W2132587122 hasConcept C2777714996 @default.
- W2132587122 hasConcept C2778917391 @default.
- W2132587122 hasConcept C42219234 @default.
- W2132587122 hasConcept C56283660 @default.
- W2132587122 hasConcept C71924100 @default.
- W2132587122 hasConcept C78519656 @default.
- W2132587122 hasConceptScore W2132587122C126322002 @default.
- W2132587122 hasConceptScore W2132587122C127413603 @default.
- W2132587122 hasConceptScore W2132587122C136936797 @default.
- W2132587122 hasConceptScore W2132587122C18206936 @default.
- W2132587122 hasConceptScore W2132587122C200457457 @default.
- W2132587122 hasConceptScore W2132587122C27101514 @default.
- W2132587122 hasConceptScore W2132587122C2777714996 @default.
- W2132587122 hasConceptScore W2132587122C2778917391 @default.
- W2132587122 hasConceptScore W2132587122C42219234 @default.
- W2132587122 hasConceptScore W2132587122C56283660 @default.
- W2132587122 hasConceptScore W2132587122C71924100 @default.
- W2132587122 hasConceptScore W2132587122C78519656 @default.
- W2132587122 hasIssue "4" @default.
- W2132587122 hasLocation W21325871221 @default.
- W2132587122 hasLocation W21325871222 @default.
- W2132587122 hasOpenAccess W2132587122 @default.
- W2132587122 hasPrimaryLocation W21325871221 @default.
- W2132587122 hasRelatedWork W2018616850 @default.
- W2132587122 hasRelatedWork W2041363394 @default.
- W2132587122 hasRelatedWork W2052888800 @default.
- W2132587122 hasRelatedWork W2053124886 @default.
- W2132587122 hasRelatedWork W2075625674 @default.
- W2132587122 hasRelatedWork W2077341242 @default.
- W2132587122 hasRelatedWork W2079306886 @default.
- W2132587122 hasRelatedWork W2132587122 @default.
- W2132587122 hasRelatedWork W2168405495 @default.
- W2132587122 hasRelatedWork W2400456127 @default.
- W2132587122 hasVolume "63" @default.
- W2132587122 isParatext "false" @default.
- W2132587122 isRetracted "false" @default.
- W2132587122 magId "2132587122" @default.
- W2132587122 workType "article" @default.