FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2132600827> ?p ?o ?g. }

• W2132600827 endingPage "23" @default.
• W2132600827 startingPage "15" @default.
• W2132600827 abstract "Cyclooxygenase (COX) inhibitors, already widely used to reduce fever, inflammation and pain, are under increasing consideration as potential agents for the prevention and treatment of neoplasia. As COX‐2 was detected in human and canine osteosarcomas, we have evaluated the effect of the preferential COX‐2 inhibitor meloxicam on an established D‐17 canine osteosarcoma cell line, which expressed, as well as COX‐1 and COX‐2 also COX‐3 (as demonstrated by Western blot). An XTT proliferation kit was used to assess surviving cells after drug treatment. At low concentrations (1, 2, 4 and 10 μ m ) meloxicam caused an increase in cell numbers while a marked anti‐proliferative effect was observed at higher concentrations (100, 200 μ m ) after 3 days and also 3 weeks of incubation. The chemotherapeutic drug doxorubicin showed a cytotoxic effect at all concentrations (60–1920 n m ). Exposure of tumour cells to combinations of meloxicam and doxorubicin revealed synergistic effects (with 240 n m doxorubicin), as well as sub‐additive and antagonistic results, especially if combined with concentrations of meloxicam typically found in serum. Care should be taken in concluding, on the basis of one in vitro study, that meloxicam does not have a role in the treatment of canine osteosarcomas given that the results from in vivo studies may differ." @default.
• W2132600827 created "2016-06-24" @default.
• W2132600827 creator A5004838844 @default.
• W2132600827 creator A5018735325 @default.
• W2132600827 creator A5056707977 @default.
• W2132600827 creator A5061262968 @default.
• W2132600827 creator A5062222743 @default.
• W2132600827 creator A5079881809 @default.
• W2132600827 creator A5081019133 @default.
• W2132600827 creator A5091519172 @default.
• W2132600827 date "2006-01-11" @default.
• W2132600827 modified "2023-09-29" @default.
• W2132600827 title "In vitro effects of meloxicam with or without doxorubicin on canine osteosarcoma cells" @default.
• W2132600827 cites W1648593433 @default.
• W2132600827 cites W1968845514 @default.
• W2132600827 cites W1969810057 @default.
• W2132600827 cites W1973407203 @default.
• W2132600827 cites W1976484281 @default.
• W2132600827 cites W1980923118 @default.
• W2132600827 cites W1986616957 @default.
• W2132600827 cites W1991507936 @default.
• W2132600827 cites W1995000761 @default.
• W2132600827 cites W1995204028 @default.
• W2132600827 cites W1996174176 @default.
• W2132600827 cites W2000307014 @default.
• W2132600827 cites W2003719859 @default.
• W2132600827 cites W2009228494 @default.
• W2132600827 cites W2010875436 @default.
• W2132600827 cites W2022755955 @default.
• W2132600827 cites W2024289681 @default.
• W2132600827 cites W2033687485 @default.
• W2132600827 cites W2042207719 @default.
• W2132600827 cites W2043707891 @default.
• W2132600827 cites W2047841570 @default.
• W2132600827 cites W2050658186 @default.
• W2132600827 cites W2054137985 @default.
• W2132600827 cites W2065897557 @default.
• W2132600827 cites W207225460 @default.
• W2132600827 cites W2075607397 @default.
• W2132600827 cites W2090492427 @default.
• W2132600827 cites W2097997344 @default.
• W2132600827 cites W2117774985 @default.
• W2132600827 cites W2125713366 @default.
• W2132600827 cites W2127558096 @default.
• W2132600827 cites W2139199726 @default.
• W2132600827 cites W2149987837 @default.
• W2132600827 cites W2150966393 @default.
• W2132600827 cites W2152838953 @default.
• W2132600827 cites W2158686638 @default.
• W2132600827 cites W2318688094 @default.
• W2132600827 cites W4233149709 @default.
• W2132600827 cites W4235997245 @default.
• W2132600827 cites W4237119758 @default.
• W2132600827 cites W4248580402 @default.
• W2132600827 cites W4249208799 @default.
• W2132600827 cites W4293247451 @default.
• W2132600827 doi "https://doi.org/10.1111/j.1365-2885.2006.00704.x" @default.
• W2132600827 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16420297" @default.
• W2132600827 hasPublicationYear "2006" @default.
• W2132600827 type Work @default.
• W2132600827 sameAs 2132600827 @default.
• W2132600827 citedByCount "24" @default.
• W2132600827 countsByYear W21326008272012 @default.
• W2132600827 countsByYear W21326008272013 @default.
• W2132600827 countsByYear W21326008272014 @default.
• W2132600827 countsByYear W21326008272015 @default.
• W2132600827 countsByYear W21326008272016 @default.
• W2132600827 countsByYear W21326008272017 @default.
• W2132600827 countsByYear W21326008272018 @default.
• W2132600827 countsByYear W21326008272019 @default.
• W2132600827 countsByYear W21326008272020 @default.
• W2132600827 countsByYear W21326008272022 @default.
• W2132600827 crossrefType "journal-article" @default.
• W2132600827 hasAuthorship W2132600827A5004838844 @default.
• W2132600827 hasAuthorship W2132600827A5018735325 @default.
• W2132600827 hasAuthorship W2132600827A5056707977 @default.
• W2132600827 hasAuthorship W2132600827A5061262968 @default.
• W2132600827 hasAuthorship W2132600827A5062222743 @default.
• W2132600827 hasAuthorship W2132600827A5079881809 @default.
• W2132600827 hasAuthorship W2132600827A5081019133 @default.
• W2132600827 hasAuthorship W2132600827A5091519172 @default.
• W2132600827 hasConcept C126322002 @default.
• W2132600827 hasConcept C150903083 @default.
• W2132600827 hasConcept C181199279 @default.
• W2132600827 hasConcept C185592680 @default.
• W2132600827 hasConcept C202751555 @default.
• W2132600827 hasConcept C207001950 @default.
• W2132600827 hasConcept C2776694085 @default.
• W2132600827 hasConcept C2777760704 @default.
• W2132600827 hasConcept C2779689624 @default.
• W2132600827 hasConcept C2779751750 @default.
• W2132600827 hasConcept C2780035454 @default.
• W2132600827 hasConcept C2781303535 @default.
• W2132600827 hasConcept C502942594 @default.
• W2132600827 hasConcept C55493867 @default.
• W2132600827 hasConcept C71924100 @default.
• W2132600827 hasConcept C86803240 @default.
• W2132600827 hasConcept C98274493 @default.

• next