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• W2132652514 abstract "Objectives: Varicoceles are the most often treated cause of male infertility. Controversy remains, however, regarding the pathophysiological mechanisms caused by varicocele. We sought to evaluate vascular flow using a highly sensitive ultrasonic device, power Doppler, and analyzed the images using programs we wrote in IDL (Interactive Data Language).Methods: 20 men with a history of male infertility were evaluated, as well as 4 normal controls. These men underwent a physical exam as well as a scrotal ultrasound to evaluate or rule out a varicocele. Using the IDL program we were able to analyze the blood flow of both the affected testicle as well as the contralateral unaffected testicle.Results: A decrease in blood flow recorded by IDL image analysis was noted in the testicle associated with the varicocele when compared to the unaffected testicle. The velocity and resistance to arterial flow in the affected testis were also not different than in the contralateral side or than in the normal controls.Conclusion: The current scientific consensus is that varicoceles cause male infertility. Many theories exist regarding the pathophysiological effect of varicoceles. By IDL image analysis of power Doppler images we detected decreased flow in the affected testis without an increase in resistance in the affected testicle. Thus, the use of the highly sensitive ultrasonic technique of power Doppler combined with image analysis using IDL further supports the hypothesis that vascular compromise invokes the pathological changes of varicocele that are associated with male infertility. Objectives: Varicoceles are the most often treated cause of male infertility. Controversy remains, however, regarding the pathophysiological mechanisms caused by varicocele. We sought to evaluate vascular flow using a highly sensitive ultrasonic device, power Doppler, and analyzed the images using programs we wrote in IDL (Interactive Data Language). Methods: 20 men with a history of male infertility were evaluated, as well as 4 normal controls. These men underwent a physical exam as well as a scrotal ultrasound to evaluate or rule out a varicocele. Using the IDL program we were able to analyze the blood flow of both the affected testicle as well as the contralateral unaffected testicle. Results: A decrease in blood flow recorded by IDL image analysis was noted in the testicle associated with the varicocele when compared to the unaffected testicle. The velocity and resistance to arterial flow in the affected testis were also not different than in the contralateral side or than in the normal controls. Conclusion: The current scientific consensus is that varicoceles cause male infertility. Many theories exist regarding the pathophysiological effect of varicoceles. By IDL image analysis of power Doppler images we detected decreased flow in the affected testis without an increase in resistance in the affected testicle. Thus, the use of the highly sensitive ultrasonic technique of power Doppler combined with image analysis using IDL further supports the hypothesis that vascular compromise invokes the pathological changes of varicocele that are associated with male infertility." @default.
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• W2132652514 date "2000-09-01" @default.
• W2132652514 modified "2023-09-30" @default.
• W2132652514 title "Quantitative Assessment of Vascular Flow in Testes of Infertility Patients With Varicocele Using Power Doppler and Image Analysis" @default.
• W2132652514 doi "https://doi.org/10.1016/s0015-0282(00)01433-3" @default.
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