FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2132863158> ?p ?o ?g. }

• W2132863158 endingPage "186" @default.
• W2132863158 startingPage "181" @default.
• W2132863158 abstract "The HBx protein of hepatitis B virus has been shown to induce hepatocellular carcinoma in transgenic mice as direct evidence for its involvement in hepatocarcinogenesis. In these transgenic mice, however, it is not clear why hepatocytes do not acquire a neoplastic phenotype by 13 months old despite the continuous growth stimulation by the HBx protein from 2 months old. In this study, we show that the accelerated proliferation of hepatocytes is counterbalanced by apoptosis, which maintains liver homeostasis. A decrease in the extent of apoptosis seems to precede the emergence of neoplasia in the transgenic mouse liver. The disappearance or block of apoptotic signals, which may be the result of additional genetic or epigenetic aberrations, may result in the preneoplastic hepatocytes becoming neoplastic." @default.
• W2132863158 created "2016-06-24" @default.
• W2132863158 creator A5021328401 @default.
• W2132863158 creator A5046522736 @default.
• W2132863158 creator A5048379128 @default.
• W2132863158 creator A5056761543 @default.
• W2132863158 creator A5072987336 @default.
• W2132863158 creator A5086161769 @default.
• W2132863158 creator A5088557295 @default.
• W2132863158 date "1998-12-01" @default.
• W2132863158 modified "2023-10-03" @default.
• W2132863158 title "Compensatory apoptosis in preneoplastic liver of a transgenic mouse model for viral hepatocarcinogenesis" @default.
• W2132863158 cites W1591696218 @default.
• W2132863158 cites W1966683022 @default.
• W2132863158 cites W1969484786 @default.
• W2132863158 cites W1971470590 @default.
• W2132863158 cites W1983796564 @default.
• W2132863158 cites W1985022589 @default.
• W2132863158 cites W1986150533 @default.
• W2132863158 cites W1987536971 @default.
• W2132863158 cites W1991355519 @default.
• W2132863158 cites W1996884717 @default.
• W2132863158 cites W2002503549 @default.
• W2132863158 cites W2005790594 @default.
• W2132863158 cites W2019900532 @default.
• W2132863158 cites W2032781689 @default.
• W2132863158 cites W2053706911 @default.
• W2132863158 cites W2070490299 @default.
• W2132863158 cites W2075049955 @default.
• W2132863158 cites W2076685716 @default.
• W2132863158 cites W2132969614 @default.
• W2132863158 cites W2138302361 @default.
• W2132863158 cites W334309946 @default.
• W2132863158 doi "https://doi.org/10.1016/s0304-3835(98)00252-3" @default.
• W2132863158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10025879" @default.
• W2132863158 hasPublicationYear "1998" @default.
• W2132863158 type Work @default.
• W2132863158 sameAs 2132863158 @default.
• W2132863158 citedByCount "58" @default.
• W2132863158 countsByYear W21328631582012 @default.
• W2132863158 countsByYear W21328631582013 @default.
• W2132863158 countsByYear W21328631582015 @default.
• W2132863158 countsByYear W21328631582016 @default.
• W2132863158 countsByYear W21328631582017 @default.
• W2132863158 countsByYear W21328631582018 @default.
• W2132863158 crossrefType "journal-article" @default.
• W2132863158 hasAuthorship W2132863158A5021328401 @default.
• W2132863158 hasAuthorship W2132863158A5046522736 @default.
• W2132863158 hasAuthorship W2132863158A5048379128 @default.
• W2132863158 hasAuthorship W2132863158A5056761543 @default.
• W2132863158 hasAuthorship W2132863158A5072987336 @default.
• W2132863158 hasAuthorship W2132863158A5086161769 @default.
• W2132863158 hasAuthorship W2132863158A5088557295 @default.
• W2132863158 hasConcept C102230213 @default.
• W2132863158 hasConcept C104317684 @default.
• W2132863158 hasConcept C121608353 @default.
• W2132863158 hasConcept C127716648 @default.
• W2132863158 hasConcept C141035611 @default.
• W2132863158 hasConcept C190283241 @default.
• W2132863158 hasConcept C203014093 @default.
• W2132863158 hasConcept C2522874641 @default.
• W2132863158 hasConcept C2776231280 @default.
• W2132863158 hasConcept C2778019345 @default.
• W2132863158 hasConcept C2780593183 @default.
• W2132863158 hasConcept C41091548 @default.
• W2132863158 hasConcept C502942594 @default.
• W2132863158 hasConcept C54355233 @default.
• W2132863158 hasConcept C555283112 @default.
• W2132863158 hasConcept C67567795 @default.
• W2132863158 hasConcept C86803240 @default.
• W2132863158 hasConceptScore W2132863158C102230213 @default.
• W2132863158 hasConceptScore W2132863158C104317684 @default.
• W2132863158 hasConceptScore W2132863158C121608353 @default.
• W2132863158 hasConceptScore W2132863158C127716648 @default.
• W2132863158 hasConceptScore W2132863158C141035611 @default.
• W2132863158 hasConceptScore W2132863158C190283241 @default.
• W2132863158 hasConceptScore W2132863158C203014093 @default.
• W2132863158 hasConceptScore W2132863158C2522874641 @default.
• W2132863158 hasConceptScore W2132863158C2776231280 @default.
• W2132863158 hasConceptScore W2132863158C2778019345 @default.
• W2132863158 hasConceptScore W2132863158C2780593183 @default.
• W2132863158 hasConceptScore W2132863158C41091548 @default.
• W2132863158 hasConceptScore W2132863158C502942594 @default.
• W2132863158 hasConceptScore W2132863158C54355233 @default.
• W2132863158 hasConceptScore W2132863158C555283112 @default.
• W2132863158 hasConceptScore W2132863158C67567795 @default.
• W2132863158 hasConceptScore W2132863158C86803240 @default.
• W2132863158 hasFunder F4320320912 @default.
• W2132863158 hasFunder F4320323514 @default.
• W2132863158 hasIssue "2" @default.
• W2132863158 hasLocation W21328631581 @default.
• W2132863158 hasLocation W21328631582 @default.
• W2132863158 hasOpenAccess W2132863158 @default.
• W2132863158 hasPrimaryLocation W21328631581 @default.
• W2132863158 hasRelatedWork W2008381783 @default.
• W2132863158 hasRelatedWork W2015898663 @default.
• W2132863158 hasRelatedWork W2030325265 @default.
• W2132863158 hasRelatedWork W2093019351 @default.

• next