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• W2133024469 abstract "By simultaneously measuring the bulk media and electrode interface voltages of a yeast (Saccharomyces cerevisiae) suspension subjected to an AC voltage, a yeast-dependent nonlinear response was found only near the current injection electrodes. Computer simulation of yeast near a current injection electrode found an enhanced voltage drop across the yeast near the electrode due to slowed charging of the electrode interfacial capacitance. This voltage drop is sufficient to induce conformation change in membrane proteins. Disruption of the mitochondrial electron transport chain is found to significantly change the measured nonlinear current response, suggesting nonlinear impedance can be used as a non-invasive probe of cellular metabolic activity." @default.
• W2133024469 created "2016-06-24" @default.
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• W2133024469 date "2011-04-11" @default.
• W2133024469 modified "2023-09-25" @default.
• W2133024469 title "Nonlinear Impedance of Whole Cells Near an Electrode as a Probe of Mitochondrial Activity" @default.
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• W2133024469 doi "https://doi.org/10.3390/bios1020046" @default.
• W2133024469 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4264341" @default.
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