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- W2133060717 abstract "The influence of growth hormone on mortality in adults is well known in conditions such as growth hormone deficiency and acromegaly. 1 2 In both diseases the excess mortality is principally from cardiovascular disorders, but the occurrence of malignant disorders has also been reported in acromegaly.2 To our knowledge the long term effect of physiological growth hormone on mortality in healthy adults has not been reported.We studied 864 policemen aged 48 to 52 years who did not have cardiovascular disease, diabetes, or glucose intolerance and who had complete data in the Paris prospective study.3 They were examined between 1967 and 1973 then followed for mortality until January 1989. The body mass index (weight(kg)/(height(m)2)), ratio of iliac to thigh circumference (a marker of central fat distribution), heart rate, and both diastolic and systolic blood pressures were measured and smoking habits determined. Blood samples were taken at fasting to measure cholesterol and triglyceride concentrations and mean corpuscular volume, and both at fasting …" @default.
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- W2133060717 date "1998-04-11" @default.
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- W2133060717 title "Growth hormone as a risk for premature mortality in healthy subjects: data from the Paris prospective study" @default.
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- W2133060717 doi "https://doi.org/10.1136/bmj.316.7138.1132" @default.
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