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• W2133207629 abstract "Acute osteomyelitis comprised 78 (29.3%) of the 266 major skeletal complications seen in 207 patients with sickle cell disease in a five and a half year period. Forty eight (61.5%) of the 78 patients were under the age of 15 years, and the mean age at onset was 12 years (range 9 months to 50 years). Osteomyelitis was often multifocal (in 42% of the cases) and associated with some life threatening disorders. Salmonella accounted for 50% of the 36 organisms isolated from 32 patients with bacteriologically confirmed diagnosis. The 9best guess9 antibiotic was a combination of chloramphenicol and cloxacillin. Medical treatment alone proved adequate in most cases. No deaths resulted, but 55% of the patients developed serious complications due partly to the severity of the disease and also to infection involving the epiphyses and joints." @default.
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• W2133207629 date "1986-11-01" @default.
• W2133207629 modified "2023-09-23" @default.
• W2133207629 title "Acute osteomyelitis in Nigerians with sickle cell disease." @default.
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• W2133207629 doi "https://doi.org/10.1136/ard.45.11.911" @default.
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