FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2133229267> ?p ?o ?g. }

• W2133229267 endingPage "540" @default.
• W2133229267 startingPage "537" @default.
• W2133229267 abstract "<h3>Background/aims:</h3> To determine whether four expression-related cytokine polymorphisms are associated with age-related macular degeneration (AMD). <h3>Methods:</h3> DNA from 478 cases with AMD and 555 normal controls was genotyped for the pro-inflammatory IL1β −511C/T, IL6 −174C/G, IL8 −251A/T and anti-inflammatory IL10 −1082G/A cytokine polymorphisms using the 5′ nuclease TaqMan® assay for allelic discrimination. Associations with AMD were analysed using allelic frequencies. <h3>Results:</h3> The −251A allele of the IL8 promoter gene polymorphism was more prevalent in AMD patients than controls (p<i> = </i>0.037, OR = 1.21, 95% CI = 1.01 to 1.44). Adjusting for age, sex, body mass index (BMI), current smoking and past smoking status did not alter the AMD association significantly (corrected p value = 0.043, OR = 1.23, 95% CI = 1.0 to 1.50). <h3>Conclusion:</h3> The pro-inflammatory homozygous IL8 –251AA genotype is an important risk factor for AMD. This may have implications for future therapy with biological agents that could target this cytokine." @default.
• W2133229267 created "2016-06-24" @default.
• W2133229267 creator A5002940859 @default.
• W2133229267 creator A5016709527 @default.
• W2133229267 creator A5027679064 @default.
• W2133229267 creator A5042478831 @default.
• W2133229267 creator A5047453258 @default.
• W2133229267 creator A5059732404 @default.
• W2133229267 creator A5072541133 @default.
• W2133229267 date "2008-02-29" @default.
• W2133229267 modified "2023-09-27" @default.
• W2133229267 title "Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration" @default.
• W2133229267 cites W1572210960 @default.
• W2133229267 cites W1582471882 @default.
• W2133229267 cites W158831104 @default.
• W2133229267 cites W1964457810 @default.
• W2133229267 cites W1983873751 @default.
• W2133229267 cites W2000399151 @default.
• W2133229267 cites W2021311336 @default.
• W2133229267 cites W2025135401 @default.
• W2133229267 cites W2029790299 @default.
• W2133229267 cites W2031511203 @default.
• W2133229267 cites W2038639621 @default.
• W2133229267 cites W2052310721 @default.
• W2133229267 cites W2068186232 @default.
• W2133229267 cites W2069596824 @default.
• W2133229267 cites W2070121689 @default.
• W2133229267 cites W2089946654 @default.
• W2133229267 cites W2101771134 @default.
• W2133229267 cites W2108050710 @default.
• W2133229267 cites W2110554565 @default.
• W2133229267 cites W2113784410 @default.
• W2133229267 cites W2118094114 @default.
• W2133229267 cites W2120110441 @default.
• W2133229267 cites W2125236492 @default.
• W2133229267 cites W2138394372 @default.
• W2133229267 cites W2141089839 @default.
• W2133229267 cites W2145921423 @default.
• W2133229267 cites W2165631391 @default.
• W2133229267 cites W2317184793 @default.
• W2133229267 cites W2332938399 @default.
• W2133229267 doi "https://doi.org/10.1136/bjo.2007.123190" @default.
• W2133229267 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5993190" @default.
• W2133229267 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18310311" @default.
• W2133229267 hasPublicationYear "2008" @default.
• W2133229267 type Work @default.
• W2133229267 sameAs 2133229267 @default.
• W2133229267 citedByCount "68" @default.
• W2133229267 countsByYear W21332292672012 @default.
• W2133229267 countsByYear W21332292672013 @default.
• W2133229267 countsByYear W21332292672014 @default.
• W2133229267 countsByYear W21332292672015 @default.
• W2133229267 countsByYear W21332292672016 @default.
• W2133229267 countsByYear W21332292672017 @default.
• W2133229267 countsByYear W21332292672018 @default.
• W2133229267 countsByYear W21332292672020 @default.
• W2133229267 countsByYear W21332292672021 @default.
• W2133229267 countsByYear W21332292672022 @default.
• W2133229267 countsByYear W21332292672023 @default.
• W2133229267 crossrefType "journal-article" @default.
• W2133229267 hasAuthorship W2133229267A5002940859 @default.
• W2133229267 hasAuthorship W2133229267A5016709527 @default.
• W2133229267 hasAuthorship W2133229267A5027679064 @default.
• W2133229267 hasAuthorship W2133229267A5042478831 @default.
• W2133229267 hasAuthorship W2133229267A5047453258 @default.
• W2133229267 hasAuthorship W2133229267A5059732404 @default.
• W2133229267 hasAuthorship W2133229267A5072541133 @default.
• W2133229267 hasBestOaLocation W21332292672 @default.
• W2133229267 hasConcept C101762097 @default.
• W2133229267 hasConcept C104317684 @default.
• W2133229267 hasConcept C118487528 @default.
• W2133229267 hasConcept C126322002 @default.
• W2133229267 hasConcept C135763542 @default.
• W2133229267 hasConcept C143660080 @default.
• W2133229267 hasConcept C149737253 @default.
• W2133229267 hasConcept C150194340 @default.
• W2133229267 hasConcept C180754005 @default.
• W2133229267 hasConcept C203014093 @default.
• W2133229267 hasConcept C2776403814 @default.
• W2133229267 hasConcept C2778690821 @default.
• W2133229267 hasConcept C2780221984 @default.
• W2133229267 hasConcept C49105822 @default.
• W2133229267 hasConcept C54355233 @default.
• W2133229267 hasConcept C68324877 @default.
• W2133229267 hasConcept C71924100 @default.
• W2133229267 hasConcept C86803240 @default.
• W2133229267 hasConceptScore W2133229267C101762097 @default.
• W2133229267 hasConceptScore W2133229267C104317684 @default.
• W2133229267 hasConceptScore W2133229267C118487528 @default.
• W2133229267 hasConceptScore W2133229267C126322002 @default.
• W2133229267 hasConceptScore W2133229267C135763542 @default.
• W2133229267 hasConceptScore W2133229267C143660080 @default.
• W2133229267 hasConceptScore W2133229267C149737253 @default.
• W2133229267 hasConceptScore W2133229267C150194340 @default.
• W2133229267 hasConceptScore W2133229267C180754005 @default.
• W2133229267 hasConceptScore W2133229267C203014093 @default.
• W2133229267 hasConceptScore W2133229267C2776403814 @default.
• W2133229267 hasConceptScore W2133229267C2778690821 @default.

• next