FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2133239024> ?p ?o ?g. }

• W2133239024 endingPage "517" @default.
• W2133239024 startingPage "512" @default.
• W2133239024 abstract "<h3>Background:</h3> Fisher syndrome (FS) is characterised by a triad of ophthalmoplegia, ataxia and areflexia. The lesion sites responsible for ataxia and ophthalmoplegia in FS require further exploration. The aim of this study was to determine the involvement of the central nervous system in FS using ¹⁸F-fluorodeoxyglucose-positron emission tomography (FDG-PET). <h3>Methods:</h3> Cerebral glucose metabolism in 10 patients with FS was compared with that of 60 age and sex matched normal controls using PET. For individual analyses, 15 age and sex matched controls were selected from the control group. Patients also underwent MRI of the brain and measurement of serum anti-GQ1b antibody. <h3>Results:</h3> Group analyses revealed increased metabolism in the cerebellar vermis and hemispheres, pontine tegmentum, midbrain tectum, left thalamus and right inferior frontal cortex (p<0.001, uncorrected). In contrast, the visual association cortices (Brodmann areas 18 and 19) showed decreased metabolism bilaterally. Individual analyses disclosed hypermetabolism in the cerebellar vermis or hemispheres (n = 7), inferior frontal cortex (n = 5) and brainstem (n = 4, p<0.005, uncorrected). A negative correlation between the cerebellar hypermetabolism and the interval from symptom onset to PET (r = −0.745, p = 0.013) was also found. Hypermetabolism was normalised on follow-up PET with an improvement in ophthalmoplegia and ataxia in one patient. <h3>Conclusions:</h3> These findings indicate involvement of the central nervous system in FS, and the hypermetabolism in the cerebellum and brainstem suggests an antibody associated acute inflammatory process as a mechanism of this autoimmune disorder." @default.
• W2133239024 created "2016-06-24" @default.
• W2133239024 creator A5005017390 @default.
• W2133239024 creator A5016726874 @default.
• W2133239024 creator A5045337799 @default.
• W2133239024 creator A5080456346 @default.
• W2133239024 creator A5089770011 @default.
• W2133239024 creator A5091371112 @default.
• W2133239024 date "2009-04-09" @default.
• W2133239024 modified "2023-10-16" @default.
• W2133239024 title "Cerebral glucose metabolism in Fisher syndrome" @default.
• W2133239024 cites W1561865339 @default.
• W2133239024 cites W1967992285 @default.
• W2133239024 cites W1980716514 @default.
• W2133239024 cites W1984190502 @default.
• W2133239024 cites W1986646886 @default.
• W2133239024 cites W1999503011 @default.
• W2133239024 cites W2008713635 @default.
• W2133239024 cites W2011562820 @default.
• W2133239024 cites W2012884785 @default.
• W2133239024 cites W2019048511 @default.
• W2133239024 cites W2020211363 @default.
• W2133239024 cites W2033525210 @default.
• W2133239024 cites W2038528453 @default.
• W2133239024 cites W2050777124 @default.
• W2133239024 cites W2051409201 @default.
• W2133239024 cites W2059268862 @default.
• W2133239024 cites W2060656629 @default.
• W2133239024 cites W2060838010 @default.
• W2133239024 cites W2061064015 @default.
• W2133239024 cites W2074261740 @default.
• W2133239024 cites W2078338858 @default.
• W2133239024 cites W2080980181 @default.
• W2133239024 cites W2082209042 @default.
• W2133239024 cites W2098286607 @default.
• W2133239024 cites W2107283998 @default.
• W2133239024 cites W2120034717 @default.
• W2133239024 cites W2128385923 @default.
• W2133239024 cites W2128754315 @default.
• W2133239024 cites W2132398409 @default.
• W2133239024 cites W2136836119 @default.
• W2133239024 cites W2145780484 @default.
• W2133239024 cites W2151161564 @default.
• W2133239024 cites W2166104162 @default.
• W2133239024 cites W2181388613 @default.
• W2133239024 cites W2339219920 @default.
• W2133239024 cites W2464345368 @default.
• W2133239024 doi "https://doi.org/10.1136/jnnp.2008.154765" @default.
• W2133239024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19066195" @default.
• W2133239024 hasPublicationYear "2009" @default.
• W2133239024 type Work @default.
• W2133239024 sameAs 2133239024 @default.
• W2133239024 citedByCount "33" @default.
• W2133239024 countsByYear W21332390242012 @default.
• W2133239024 countsByYear W21332390242013 @default.
• W2133239024 countsByYear W21332390242015 @default.
• W2133239024 countsByYear W21332390242017 @default.
• W2133239024 countsByYear W21332390242018 @default.
• W2133239024 countsByYear W21332390242019 @default.
• W2133239024 countsByYear W21332390242020 @default.
• W2133239024 countsByYear W21332390242021 @default.
• W2133239024 countsByYear W21332390242022 @default.
• W2133239024 countsByYear W21332390242023 @default.
• W2133239024 crossrefType "journal-article" @default.
• W2133239024 hasAuthorship W2133239024A5005017390 @default.
• W2133239024 hasAuthorship W2133239024A5016726874 @default.
• W2133239024 hasAuthorship W2133239024A5045337799 @default.
• W2133239024 hasAuthorship W2133239024A5080456346 @default.
• W2133239024 hasAuthorship W2133239024A5089770011 @default.
• W2133239024 hasAuthorship W2133239024A5091371112 @default.
• W2133239024 hasBestOaLocation W21332390242 @default.
• W2133239024 hasConcept C118552586 @default.
• W2133239024 hasConcept C126322002 @default.
• W2133239024 hasConcept C126838900 @default.
• W2133239024 hasConcept C134018914 @default.
• W2133239024 hasConcept C24566897 @default.
• W2133239024 hasConcept C2777464067 @default.
• W2133239024 hasConcept C2779246727 @default.
• W2133239024 hasConcept C2779652256 @default.
• W2133239024 hasConcept C2780148635 @default.
• W2133239024 hasConcept C2780168142 @default.
• W2133239024 hasConcept C2780906641 @default.
• W2133239024 hasConcept C529278444 @default.
• W2133239024 hasConcept C551621295 @default.
• W2133239024 hasConcept C552161191 @default.
• W2133239024 hasConcept C71924100 @default.
• W2133239024 hasConceptScore W2133239024C118552586 @default.
• W2133239024 hasConceptScore W2133239024C126322002 @default.
• W2133239024 hasConceptScore W2133239024C126838900 @default.
• W2133239024 hasConceptScore W2133239024C134018914 @default.
• W2133239024 hasConceptScore W2133239024C24566897 @default.
• W2133239024 hasConceptScore W2133239024C2777464067 @default.
• W2133239024 hasConceptScore W2133239024C2779246727 @default.
• W2133239024 hasConceptScore W2133239024C2779652256 @default.
• W2133239024 hasConceptScore W2133239024C2780148635 @default.
• W2133239024 hasConceptScore W2133239024C2780168142 @default.
• W2133239024 hasConceptScore W2133239024C2780906641 @default.
• W2133239024 hasConceptScore W2133239024C529278444 @default.

• next