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- W2133282671 endingPage "475" @default.
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- W2133282671 abstract "Abstract There is an urgent need for universal influenza vaccines that can control emerging pandemic influenza virus threats without the need to generate new vaccines for each strain. Neutralizing Abs to the influenza virus hemagglutinin glycoprotein are effective at controlling influenza infection but generally target highly variable regions. Abs that can mediate other functions, such as killing influenza-infected cells and activating innate immune responses (termed “Ab-dependent cellular cytotoxicity [ADCC]-mediating Abs”), may assist in protective immunity to influenza. ADCC-mediating Abs can target more conserved regions of influenza virus proteins and recognize a broader array of influenza strains. We review recent research on influenza-specific ADCC Abs and their potential role in improved influenza-vaccination strategies." @default.
- W2133282671 created "2016-06-24" @default.
- W2133282671 creator A5054025307 @default.
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- W2133282671 date "2014-07-15" @default.
- W2133282671 modified "2023-10-02" @default.
- W2133282671 title "Influenza-Specific Antibody-Dependent Cellular Cytotoxicity: Toward a Universal Influenza Vaccine" @default.
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- W2133282671 doi "https://doi.org/10.4049/jimmunol.1400432" @default.
- W2133282671 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24994909" @default.
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